Results 41 to 50 of about 31,480,937 (161)

The HLA-DRA*0102 allele: correct nucleotide sequence and associated HLA haplotypes

, 2002
Here we correct the nucleotide sequence of a single known variant of the HLA-DRA gene. We show that the coding regions of the HLA-DRA*0101 and HLA-DRA*0102 alleles do not differ at two codons as reported previously, but only in codon 217.
Marsh, SGE, Marsh, S. G., Kralovicova, J, Hammarstrom, L, Kralovicova, J., Hammarstrom, L., Vorechovsky, I, Waller, M. J., Vorechovsky, I., Waller, MJ   +9 more
core   +1 more source

E5 protein of human papillomavirus type 16 selectively downregulates surface HLA class I [PDF]

, 2005
Papillomaviruses have evolved mechanisms that result in escape from host immune surveillance. The E5 protein is expressed early in papillomavirus infection in the deep layers of the infected epithelium.
Marchetti, Barbara, O'Brien, P.M., Ashrafi, G. Hossein, Haghshenas, Mohammad R., O'Brien, Philippa M., Ashrafi, G.H., Haghshenas, M.R., Campo, M.S., Marchetti, B., Campo, M. Saveria   +9 more
core   +1 more source

HLA-E-restricted cross-recognition of allogeneic endothelial cells by CMV-associated CD8 T cells: a potential risk factor following transplantation. [PDF]

PLoS ONE, 2012
Although association between CMV infection and allograft rejection is well admitted, the precise mechanisms involved remain uncertain. Here, we report the characterization of an alloreactive HLA-E-restricted CD8 T cell population that was detected in the
Mathilde Allard, Pierre Tonnerre, Steven Nedellec, Romain Oger, Alexis Morice, Yannick Guilloux, Elisabeth Houssaint, Béatrice Charreau, Nadine Gervois   +8 more
doaj   +1 more source

Real-Time Distributed Aircraft Simulation through HLA [PDF]

, 2012
This paper presents some ongoing researches carried out in the context of the PRISE (Research Platform for Embedded Systems Engineering) Project. This platform has been designed to evaluate and validate new embedded system concepts and techniques through
Leconte, Régine, Gervais, Clément, Clement Gervais, Regine Leconte, Pierre Siron, Saussié, David, Chaudron, Jean-Baptiste, Siron, Pierre, David Saussie, Jean-Baptise Chaudron, Chaudron, Jean-Baptise   +10 more
core   +1 more source

Mtb HLA-E-tetramer-sorted CD8+ T cells have a diverse TCR repertoire

iScience
Summary: HLA-E molecules can present self- and pathogen-derived peptides to both natural killer (NK) cells and T cells. T cells that recognize HLA-E peptides via their T cell receptor (TCR) are termed donor-unrestricted T cells due to restricted allelic ...
Linda Voogd, Anne M.H.F. Drittij, Calinda K.E. Dingenouts, Kees L.M.C. Franken, Vincent van Unen, Krista E. van Meijgaarden, Paula Ruibal, Renate S. Hagedoorn, Judith A. Leitner, Peter Steinberger, Mirjam H.M. Heemskerk, Mark M. Davis, Thomas J. Scriba, Tom H.M. Ottenhoff, Simone A. Joosten   +14 more
doaj   +1 more source

Acute disseminated encephalomyelitis: clinical features, HLA DRB1*1501, HLA DRB1*1503, HLA DQA1*0102, HLA DQB1*0602, and HLA DPA1*0301 allelic association study Encefalomielite aguda disseminada: características clínicas e estudo de associação com os alelos HLA DRB1*1501, HLA DRB1*1503, HLA DQA1*0102, HLA DQB1*0602 e DPA1*0301

Arquivos de Neuro-Psiquiatria, 2009
We evaluated the frequency, demographic, clinical, disability evolution and genetic association of HLA DRB1*1501, DRB1*1503, DQA1*0102, DQB1*0602 and DPA1*0301 alleles in patients diagnosed as acute disseminated encephalomyelitis (ADEM) among a ...
Soniza Vieira Alves-Leon, Maria Lucia Veluttini-Pimentel, Maria Emmerick Gouveia, Fabíola Rachid Malfetano, Emerson L. Gaspareto, Marcos P. Alvarenga, Izabel Frugulhetti, Thereza Quirico-Santos   +7 more
doaj   +1 more source

HLA-E circulating and genetic determinants in schizophrenia and bipolar disorder

Scientific Reports, 2021
Schizophrenia (SZ) and bipolar disorders (BD) are severe mental illnesses that lack reliable biomarkers to guide diagnosis and management. As immune dysregulation is associated with these disorders, we utilized the immunoregulatory functions of the ...
Wahid Boukouaci, Mohamed Lajnef, Jean-Romain Richard, Ching-Lien Wu, Jihène Bouassida, Ismail Rafik, Marianne Foiselle, Céline Straczek, Esma Mezouad, Soumia Naamoune, Sofiane Salah, Mohamed Amin Bencharif, Arij Ben Chaaben, Caroline Barau, Philippe Le Corvoisier, Marion Leboyer, Ryad Tamouza   +16 more
doaj   +1 more source

Evaluation of Baciloscopy, Cultivation and Polimerasa Chain Reaction for the Diagnostic of Lung Tuberculosis

Kasmera, 2005
The utility of baciloscopy, cultivation and Polimerasa Chain Reaction of (PCR) was evaluated in 31 sputum samples, of patient of both sexes, without distinction of etnial grup and ages between 17 and 80 years, with clinical manifestations, discoveries ...
Orlando Nava Paz, Manzur Hassanhi, Lisbeth Prieto   +2 more
doaj  

O papel do complexo principal de histocompatibilidade na fisiologia da gravidez e na patogênese de complicações obstétricas Major histocompatibility complex: its role in the physiology of pregnancy and in the pathogenic mechanisms of obstetric complications

Revista Brasileira de Saúde Materno Infantil, 2007
Este trabalho tem por objetivo discutir a estrutura e função dos Antígenos Leucocitários Humanos (HLA), seus métodos de detecção, nomenclatura e os mecanismos imunopatológicos que o associam com a fisiologia da gestação e morbidades obstétricas.
Crésio Alves, Sâmia Veiga, Maria Betânia P. Toralles, Antônio Carlos Vieira Lopes   +3 more
doaj   +1 more source

Estudo comparativo entre reação de Mitsuda e antígenos leucocitários humanos em pacientes hansenianos Comparative study between the Mitsuda test and the human leukocyte antigens in leprosy patients

Revista da Sociedade Brasileira de Medicina Tropical, 2007
Neste estudo, propomos comparar o teste cutâneo de Mitsuda e os alelos HLA-DR2/HLA-DR3 e HLA-DQ1 relacionados com as formas clínicas da hanseníase em 176 pacientes (50 TT, 50 LL e 76 B).
Fabiana Covolo de Souza, Elaine Valim Camarinha Marcos, Somei Ura, Paula Araújo Opromolla, Maria Esther Salles Nogueira   +4 more
doaj   +1 more source