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Non-Classical HLA-G Antigen and Its Role in the Cancer Progression
Cancer Investigation, 2006Various changes take place during the progression of cancer, some of which are favorable for tumor development and may help to escape the immunosurvillance. These include changes in the microenvironment around the developing tumor, which could be produced in response to phenotypic alterations or could modulate the expression of certain markers of tumor
Piyush, Tripathi, Suraksha, Agrawal
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Human Antigen Leucocyte (HLA)-G and HLA-E are differentially expressed in pancreatic disorders
Human Immunology, 2019Little information is available regarding the expression of the immunomodulatory Human Leukocyte Antigen (HLA)-G and -E molecules in pancreatic disorders.To analyze HLA-G and -E expression in specimens of alcoholic chronic pancreatitis (ACP), idiopathic chronic pancreatitis (ICP), type 1 (T1D) and type 2 diabetes (T2D) and in histologically normal ...
Bruna Cristina, Bertol +4 more
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Human Leukocyte Antigen-G (HLA-G) 3'UTR haplotypes in kidney transplantation
2021HLA-G is a non-classical HLA molecule involved in tolerance and considered an immune checkpoint in transplantation. HLA-G 14 bp ins/del, consisting of an insertion/ deletion of 14 bp in exon 8, is one of the most studied HLA-G gene polymorphisms. In organ transplantation, it was mainly associated with the onset of immunological complications, such as ...
Daniela Piancatelli +10 more
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659 HIGH HUMAN LEUKOCYTE ANTIGEN G (HLA-G) EXPRESSION IN HEPATOCELLULAR CARCINOMA (HCC)
Journal of Hepatology, 2013A.C. Teixeira, M. Brunaldi, J.C.O. Crispim, E.A. Donadi, A.L.C. Martinelli. Internal Medicine, Surgery and Anatomy, Pathology, Faculty of Medicine of Ribeirao Preto – University of Sao Paulo, Clinical Analysis and Toxicology, Federal University of Rio Grande do Norte, Ribeirao Preto, Internal Medicine, Faculty of Medicine of Ribeirao Preto – University
A.C. Teixeira +4 more
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Expression of Human Leukocyte Antigen G (HLA-G) Correlates with Poor Prognosis in Gastric Carcinoma
Annals of Surgical Oncology, 2007We had previously demonstrated that human leukocyte antigen G (HLA-G) was expressed in a majority of primary colorectal carcinomas and that the detection of HLA-G expression had a strong and independent prognostic value for that cancer. Currently, we investigate whether or not HLA-G is also expressed in patients with gastric carcinoma and whether the ...
Shang-Mian, Yie +5 more
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Fetal Diagnosis and Therapy, 2004
<i>Objective:</i> To determine whether soluble HLA-G1 (sHLA-G1) concentrations in maternal serum and in amniotic fluid are lower at term than in the second trimester. <i>Methods:</i> In this prospective study amniotic fluid and maternal serum samples were aspirated from 21 pregnant women during genetic amniocentesis at 16–20 ...
Rinat, Hackmon +6 more
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<i>Objective:</i> To determine whether soluble HLA-G1 (sHLA-G1) concentrations in maternal serum and in amniotic fluid are lower at term than in the second trimester. <i>Methods:</i> In this prospective study amniotic fluid and maternal serum samples were aspirated from 21 pregnant women during genetic amniocentesis at 16–20 ...
Rinat, Hackmon +6 more
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Integrative oncology: Addressing the global challenges of cancer prevention and treatment
Ca-A Cancer Journal for Clinicians, 2022Jun J Mao,, Msce +2 more
exaly
No expression of human leukocyte antigen G (HLA-G) in colorectal cancer cells.
Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2004Although there is a specific antitumor immune response in the body, colorectal cancer cells progressively develop. This fact indicated that the cancer cells could have a variety of mechanisms to evade or escape the immune system. HLA-G is identified to inhibit the recognition of NK-cell in various kinds of cancers.
Kawin, Leelawat +5 more
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