Results 21 to 30 of about 313,560 (297)

Association of HLA class II alleles with suicidal behavior in a Transylvanian population

Romanian Journal of Laboratory Medicine, 2023
Background: Suicide is a complex phenomenon determined by the interaction of various risk factors. The Major Histocompatibility Complex is the most polymorphic gene cluster of the entire human genome, being linked to both the regulation of the immune ...
Vuscan Mihaela Elvira, Vica Mihaela Laura, Balici Stefana, Nicula Gheorghe Zsolt, Rusu Sergiu Ionica, Siserman Costel Vasile, Coman Horia George, Matei Horea Vladi   +7 more
doaj   +1 more source

Research and realization of RTI data transmission method based on attribute reflection [PDF]

MATEC Web of Conferences, 2020
In order to solve the error of simulation result because of data loss in VR-Link traditional simulation framework, in this paper data transfer mechanism of instance attribute on VR-Link object class is researched in detail.
Wang Long, Fang Juan, Xiao Qiang, Cai Liang   +3 more
doaj   +1 more source

Recurrent Guillain-Barré and Fisher Syndromes in Two Patients Who Were Subsequently Diagnosed with Aplastic Anemia

Case Reports in Neurology, 2020
Guillain-Barré (GBS) and Fisher (FS) syndromes rarely recur and the characteristics of recurrence have not been fully elucidated. We describe the cases of 2 patients with GBS or FS that recurred more than twice and who were subsequently diagnosed with ...
Saori Tomohara, Risa Harano, Shinichi Wada, Ikkei Ohashi, Fumitaka Yoshino, Daiki Mito, Masanori Kadowaki, Ken Takase, Takahiro Kuwashiro, Hitonori Takaba, Masahiro Yasaka, Yasushi Okada   +11 more
doaj   +1 more source

HLA-J, A SECOND INACTIVATED CLASS I HLA GENE RELATED TO HLA-G AND HLA-A

Journal of Immunology, 1992
Ragoussis and co-workers previously described a class I HLA gene (now designated HLA-J) that maps to within 50 kb of HLA-A. The nucleotide sequences of three HLA-J alleles are reported here. Comparison of the nucleotide sequences of HLA-J alleles shows this gene is more related to HLA-G, A, and H than to HLA-B, C, E, and F.
Messer, Gerald, Zemmour, Jaqueline, Orr, Harry T., Parham, P., Weiss, Elisabeth H., Girdlestone, J.   +5 more
openaire   +3 more sources

Donor – recipient selection using epitope mismatches in kidney transplantation

Бюллетень сибирской медицины, 2021
Purpose. To evaluate the potential option of selecting donor–recipient pairs by using the number of epitopemismatches.Materials and methods. An observational cohort study was carried out, which included 824 adult recipients of ABO compatible deceased ...
A. V. Vatazin, A. B. Vatazin, V. A. Stepanov   +2 more
doaj   +1 more source

SEROLOGICAL MARKERS OF CELIAC DISEASE AND HLA II ANTIGENS IN CHILDREN AND ADOLESCENTS WITH DIABETES MELLITUS TYPE 1

Вопросы современной педиатрии, 2012
We have studied incidenceof immunological markers of celiac disease in children with diabetes mellitus type 1 (DM1) and their correlation with clinical peculiarities and polymorphous alleles of HLA. It was shown that incidence of celiac markers is higher
E. O. Hennesy, T. L. Kuraeva, S. A. Prokofyev, N. B. Smirnova, Y. V. Tishina, E. V. Тitovic, V. A. Peterkova   +6 more
doaj   +1 more source

Role of HLA alleles polymorphism in systemic lupus erythematosus: A prospective study from North India

Indian Journal of Pathology and Microbiology, 2023
Background: Systemic lupus erythematosus (SLE) is a chronic autoimmune disorder and has complex etiopathogenesis. The most appropriate hypothesis states that genetic susceptibility in the presence of environmental risk factors predisposes to SLE.
Ranjan S. Rana, Bitan Naik, Mahima Yadav, Usha Singh, Anup Singh, Shailja Singh   +5 more
doaj   +1 more source

Establishment and capacity analysis of Hefei platelet donor bank with HPA and HLA high-resolution results

Zhongguo shuxue zazhi, 2022
Objective To establish a platelet donor database with HPA and HLA high resolution results in Hefei area, and to analyze the appropriate pool capacity, so as to provide support for patients with immune PTR transfusion difficulties.
Nana ZHAO, Chao WANG, Xiao PANG, Yang ZHAO, Juan YU, Rong LV   +5 more
doaj   +1 more source

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

Molecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti, Manuel Scimeca, Julia Bischof, Jonathan Woodsmith, Massimiliano Agostini, Cristina Fiorani, Yufang Shi, Eleonora Candi, Gerry Melino, Alessandro Mauriello, Giuseppe S. Sica   +10 more
wiley   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source