Expression analysis of HLA-E and NKG2A and NKG2C receptors points at a role for natural killer function in ankylosing spondylitis [PDF]
, 2018 Background. Ankylosing Spondylitis (AS) is a complex chronic inflammatory disease strongly associated with the majority of HLA-B27 alleles. HLA-E are non-classical MHC class I molecules that specifically interact with the natural killer receptors NKG2A ...
Angioni, Mm +12 more
core +1 more source
Indirect Scapholunate Ligament Repair: All Arthroscopic
Arthroscopy Techniques, 2018 The arthroscopic technique most frequently used in acute scapholunate instability is reduction and fixation with Kirschner wires. To repair the injured ligament, open surgery and dorsal capsular plication are recommended, but this procedure has the risk ...
David Bustamante Suárez de Puga, M.D. +6 more
doaj +1 more source
GUT MICROBIOTA EFFECTS IN HEMATOPOIETIC STEM CELL TRANSPLANT PATIENTS
İstanbul Tıp Fakültesi Dergisi, 2022 Objective: In our study, we analyzed gut microbiota in allo-HSCT patients and aimed to evaluate the relationship of gut microbiota with transplant complications, mainly GVHD.
Ekin Ece Gürer Kluge +6 more
doaj +1 more source
Allelic variation in HLA-B and HLA-C sequences and the evolution of the HLA-B alleles [PDF]
, 1989 Several new HLA-B (B8, B51, Bw62)- and HLA-C (Cw6, Cw7)-specific genes were isolated either as genomic cosmid or cDNA clones to study the diversity of HLA antigens.
Doerner, C. +4 more
core +1 more source
The HLA-E Gene encodes two differentially regulated Transcripts and a Cell Surface Protein [PDF]
, 1992 An HLA-E-specific oligonucleotide probe was used to study the expressioonf HLA-E. This probed etects two HLA-E transcripts, 1.8 and 2.7 kb in size, which are present in varying ratios in allt issues and cell lines investigated.
Honka, Thomas +4 more
core +1 more source
Impaired Intracellular Transport and Cell Surface Expression of Nonpolymorphic HLA-E [PDF]
, 1992 The assembly of the classical, polymorphic major histocompatibility complex class I molecules in the endoplasmic reticulum requires the presence of peptide ligands and ~2-microglobulin (~2m). Formation of this trimolecular complex is a prerequisite for e~
Johnson, Judith P. +3 more
core +1 more source
Arthroscopic Treatment of a Malunion of a Posteromedial Tubercle Fracture of the Talus
Arthroscopy Techniques, 2017 Posteromedial ankle impingement is rare and uncommonly associated with a fracture. Bone resection of the fragment is the recommended treatment. In this report, we describe the step-by-step surgical technique of arthroscopic resection of a malunion of a ...
Jesús Más Martínez, M.D. +5 more
doaj +1 more source
Factors influencing transfusion-associated HLA sensitization in patients bridged to heart transplantation using ventricular assist device. [PDF]
, 2020 BackgroundBridging heart failure patients with mechanical ventricular assist devices (VAD) enables access to transplantation. However, VAD is associated with increased risk for anti-HLA antibodies associated with rejection of subsequent allografts ...
Adler, Eric +5 more
core +1 more source
HLA-DP, HLA-DQ, and HLA-DR Have Different Requirements for Invariant Chain and HLA-DM [PDF]
Journal of Biological Chemistry, 2010 The MHC is central to the adaptive immune response. The human MHC class II is encoded by three different isotypes, HLA-DR, -DQ, and -DP, each being highly polymorphic. In contrast to HLA-DR, the intracellular assembly and trafficking of HLA-DP molecules have not been studied extensively.
Marcel, van Lith +2 more
openaire +2 more sources
HLA-DR in Cytotoxic T lymphocytes predicts breast cancer patients' response to neoadjuvant chemotherapy [PDF]
, 2018 Prediction of breast cancer response to Neoadjuvant Chemotherapy (NACT) is an urgent need to promptly direct non-responder patients to alternative therapies.
Borralho, Paula +4 more
core +2 more sources