HLA class II antibodies at the time of kidney transplantation and cardiovascular outcome : a retrospective cohort study [PDF]
, 2020 Background. The negative role of HLA class II donor-specific antibody on graft outcome is well recognized. However, the potentially negative cardiovascular effects of preformed HLA class II antibodies and donor HLA in kidney transplant recipients (KTRs)
Daniels, L +5 more
core +2 more sources
A Latent Space Model for HLA Compatibility Networks in Kidney Transplantation [PDF]
arXiv, 2022 Kidney transplantation is the preferred treatment for people suffering from end-stage renal disease. Successful kidney transplants still fail over time, known as graft failure; however, the time to graft failure, or graft survival time, can vary significantly between different recipients.
arxiv
Protective Allele for Multiple Sclerosis HLA-DRB1*01:01 Provides Kinetic Discrimination of Myelin and Exogenous Antigenic Peptides. [PDF]
, 2020 Risk of the development of multiple sclerosis (MS) is known to be increased in individuals bearing distinct class II human leukocyte antigen (HLA) variants, whereas some of them may have a protective effect.
Bashinskaya, Vitalina +19 more
core +1 more source
Computer simulation in the development of vaccines against covid-19 based on the hla-system antigens [PDF]
Клиническая практика, 2021 The genetic variability of population may explain different individual immune responses to the SARS-CoV-2 virus. The use of genome- and peptidome-based technologies makes it possible to develop vaccines by optimizing the target antigens.
Dmitry A. Vologzhanin +4 more
doaj +1 more source
Manipulation of Kondo Effect via Two-Dimensional Molecular Self-Assembly [PDF]
, 2006 We report manipulation of a Kondo resonance originated from the spin-electron interactions between a two-dimensional molecular assembly of TBrPP-Co molecules and a Cu(111) surface at 4.6 K using a low temperature scanning tunneling microscope. By manipulating nearest-neighbor molecules with a scanning tunneling microscope tip we are able to tune the ...
arxiv +1 more source
An Anti-C1s Monoclonal, TNT003, Inhibits Complement Activation Induced by Antibodies Against HLA. [PDF]
, 2015 Antibody-mediated rejection (AMR) of solid organ transplants (SOT) is characterized by damage triggered by donor-specific antibodies (DSA) binding donor Class I and II HLA (HLA-I and HLA-II) expressed on endothelial cells.
Fishbein, MC +7 more
core +1 more source
Impaired Intracellular Transport and Cell Surface Expression of Nonpolymorphic HLA-E [PDF]
, 1992 The assembly of the classical, polymorphic major histocompatibility complex class I molecules in the endoplasmic reticulum requires the presence of peptide ligands and ~2-microglobulin (~2m). Formation of this trimolecular complex is a prerequisite for e~
Johnson, Judith P. +3 more
core +1 more source
The HLA-E Gene encodes two differentially regulated Transcripts and a Cell Surface Protein [PDF]
, 1992 An HLA-E-specific oligonucleotide probe was used to study the expressioonf HLA-E. This probed etects two HLA-E transcripts, 1.8 and 2.7 kb in size, which are present in varying ratios in allt issues and cell lines investigated.
Honka, Thomas +4 more
core +1 more source
Arthroscopy, Sports Medicine, and Rehabilitation, 2020 Purpose: We aimed to determine the relationship between recreational sports and intra-articular hip injuries in an active population that had undergone hip arthroscopy for femoroacetabular impingement syndrome.
Jesus Mas Martinez, M.D. +5 more
doaj
Human leukocyte antigens and genetic susceptibility to lymphoma [PDF]
, 2015 Familial aggregation, coupled with ethnic variation in incidence, suggests that inherited susceptibility plays a role in the development of lymphoma, and the search for genetic risk factors has highlighted the contribution of the human leukocyte antigen (
Jarrett, R.F., McAulay, K.A.
core +1 more source