Results 221 to 230 of about 13,841,936 (288)

Evaluation of the AllType kit for HLA typing using the Ion Torrent S5 XL platform

HLA, 2020
HLA genotyping by next‐generation sequencing is now widely performed. We aimed at evaluating the performance of the One Lambda AllType kit using Thermo Fisher Scientific reagents on the Ion S5 XL platform.
M. Cargou, M. Ralazamahaleo, L. Blouin, I. Top, V. Elsermans, M. Andreani, G. Guidicelli, J. Visentin   +7 more
semanticscholar   +1 more source

HLA Typing in Multiple Sclerosis.

Lancet, The, 1982
A Compston
exaly   +3 more sources

Serum HLA Typing

Tissue Antigens, 1981
This paper establishes that HLA antigens can be detected in serum by lymphocytotoxicity inhibition. A score system is described which enables the degree of cytotoxicity inhibition to be quantitated. The following HLA antigens have been detected: A1, A2, A3, A11, Aw24, B5, B7, B8, B27, Bw35 and B40. It has not been possible to detect HLA‐B12.
B D, Tait, R I, Finlay, M J, Simons
openaire   +2 more sources

A new set of reagents and related software used for NGS based classical and non-classical HLA typing showing evidence for a greater HLA haplotype diversity.

Human Immunology, 2020
To evaluate the HLA typing performance of a new Long-Range PCR NGS set of reagents and its dedicated software, a panel of 41 reference homozygous cell lines from the International Histocompatibility Working Group (IHWG) and a panel of 376 volunteer bone ...
M. Alizadeh, C. Picard, C. Frassati, Alexandre Walencik, A. Gauthier, F. Bennasar, Franck Vérité, G. Semana   +7 more
semanticscholar   +1 more source

HLA Typing and Retinitis pigmentosa

Ophthalmologica, 2010
Retinitis pigmentosa is a disease whose pathogenesis remains largely obscure. A lot of evidences support the hypothesis that autoimmunity is involved, but no HLA antigen has ever been associated with retinitis pigmentosa. Ten patients with autosomal recessive retinitis pigmentosa were tissue typed for class I and II HLA antigens.
CASTAGNA, Irene Concetta, FAMA F, PETTINATO G, PALAMARA F, TROMBETTA, Costantino   +4 more
openaire   +2 more sources

Clinical utility of next generation sequencing based HLA typing for disease association and pharmacogenetic testing.

Human Immunology, 2020
HLA associations have been linked to many diseases and are important for risk assessment of drug hypersensitivity reactions. The increasing number of HLA alleles discovered generated a list of ambiguities that cannot be resolved with the current clinical
Tracie Profaizer, A. Pole, Cassandra Monds, J. Delgado, E. Lázár-Molnár   +4 more
semanticscholar   +1 more source

Two‐field resolution on‐call HLA typing for deceased donors using nanopore sequencing

HLA
The current practice of HLA genotyping in deceased donors poses challenges due to limited resolution within time constraints. Nevertheless, the assessment of compatibility between anti‐HLA sensitized recipients and mismatched donors remains a critical ...
M. Devriese, Séphora Neves da Silva, Melchior Le Mene, Julien Rouquie, V. Allain, L. Kolesár, Krisztina Rigó, L. Creary, N. Lauterbach, C. Usureau, Mathieu Dewez, Sophie Caillat-Zucman, G. Werner, J. Taupin   +13 more
semanticscholar   +1 more source

Improvement in HLA-C typing by a new sequence-specific oligonucleotides kit.

HLA, 2020
PCR-SSO (sequence-specific oligonucleotide) is commonly used for HLA-typing. We recently replaced LabType® SSO HD kit for HLA-C typing with the XR kit (OneLambda, Inc.).
M. Cargou, M. Ralazamahaleo, L. Blouin, G. Guidicelli, J. Visentin   +4 more
semanticscholar   +1 more source

HLA-B27: To Type or Not to Type?

Annals of Internal Medicine, 1980
The association between the histocompatibility antigen HLA-B27 and the seronegative spondylarthritides such as ankylosing spondylitis and Reiter's syndrome is dramatic. A question that arises in practice is, when should a clinician request HLA-B27 typing in the assessment of a patient with a rheumatologic complaint?
openaire   +2 more sources

HLA Typing in Birdshot Chorioretinopathy

American Journal of Ophthalmology, 1988
We examined 49 patients with birdshot chorioretinopathy in whom HLA typing had been performed. Of these 49 patients, 47 (95.9%) had the HLA-A29 antigen. The HLA-B12 (B44) antigen was also significantly associated with the disease, but this antigen is known to be in linkage disequilibrium with the antigen HLA-A29. The HLA-A2 antigen was less frequent in
H A, Priem, A, Kijlstra, L, Noens, G S, Baarsma, J J, De Laey, J A, Oosterhuis   +5 more
openaire   +2 more sources