Results 41 to 50 of about 45,099 (293)

Roles for Treg expansion and HMGB1 signaling through the TLR1-2-6 axis in determining the magnitude of the antigen-specific immune response to MVA85A [PDF]

, 2013
© 2013 Matsumiya et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
Helen McShane (80704), Pathan, Ansar A, Stylianou, E, Lang, Z, Stephanie A. Harris (429956), Elena Stylianou (292312), Matsumiya, Magali, Griffiths Kristin, Lang Zoe, McShane Helen, Meyer, Joel, Magali Matsumiya, Griffiths, Kristin, Zoe Lang (429954), Lang, Zoe, Ansar A Pathan, Meyer, J, Angela M. Minassian (345365), Magali Matsumiya (429952), Fletcher Helen, Harris, Stephanie A, Rowland Rosalind, Meyer Joel, Kristin Griffiths (429953), Joel Meyer, Harris, SA, McShane, H, Fletcher, Helen, McShane, Helen, Minassian, Angela M, Zoe Lang, Rowland, Rosalind, Matsumiya Magali, Minassian Angela M., Angela M Minassian, Kristin Griffiths, Pathan Ansar A., Joel Meyer (429955), Helen Fletcher, Harris Stephanie A., Rowland, R, Rosalind Rowland, Matsumiya, M, Pathan, AA, Fletcher, H, Minassian, AM, Helen Fletcher (249210), Rosalind Rowland (429957), Helen McShane, Griffiths, K, Elena Stylianou, Stephanie A Harris, Ansar A. Pathan (80697), Stylianou, Elena, Stylianou Elena   +54 more
core   +1 more source

Protein VII’s interaction with HMGB1 is not dependent on HMGB1’s interaction with DNA. [PDF]

, 2023
A. Schematic of mutHMGB1 expressed in A549∆HMGB1 cells with point mutations as indicated. B. B2H results of interaction between protein VII and mutHMGB1 constructs as indicated. C. Immunofluorescence images of full length mutHMGB1 cells as in (A) showing
Monica S. Guo (16979653), Daphne C. Avgousti (2611336), Edward A. Arnold (16979638), Laurel E. Kelnhofer-Millevolte (16979650), Robin J. Kaai (16979641), Katie Leung (16979644), Mia R. Brinkley (16979647)   +6 more
core   +1 more source

PRRSV Induces HMGB1 Phosphorylation at Threonine-51 Residue to Enhance Its Secretion

Viruses, 2022
Porcine reproductive and respiratory syndrome virus (PRRSV) induces secretion of high mobility group box 1 (HMGB1) to mediate inflammatory response that is involved in the pulmonary injury of infected pigs.
Rong Wang, Jingyi Zhang, Yu Fu, Linying Jia, Yali Zhang, Liang Bai, Weirong Wang, Daxin Cheng, Enqi Liu   +8 more
doaj   +1 more source

Multiple large foreign protein expression by a single recombinant baculovirus: a system for production of multivalent vaccines. [PDF]

, 2013
Baculovirus expression system offers the advantage of expression of several large proteins simultaneously by a single recombinant virus. To date, expression of multiple large (>100kDa) proteins has been hampered by the need to generate large constructs ...
Kanai, Yuta, Stewart, Meredith, Roy, Polly, Athmaram, T.N., Athmaram, TN   +4 more
core   +1 more source

High-Mobility Group Box 1 Induces Calcineurin-Mediated Cell Hypertrophy in Neonatal Rat Ventricular Myocytes

Mediators of Inflammation, 2012
Cardiac hypertrophy is an independent predictor of cardiovascular morbidity and mortality. In recent years, evidences suggest that high-mobility group box 1 (HMGB1) protein, an inflammatory cytokine, participates in cardiac remodeling; however, the ...
Fei-fei Su, Miao-qian Shi, Wan-gang Guo, Xiong-tao Liu, Hong-tao Wang, Zi-fan Lu, Qiang-sun Zheng   +6 more
doaj   +1 more source

Effect of High-mobility Group Box-1 on Expression of Stem Cell Markers OCT4, Sox2 and Nanog in Cervical Carcinoma

Zhongliu Fangzhi Yanjiu, 2018
Objective To investigate the role of High-mobility group box-1 (HMGB1) protein in regulating the expression of cancer stem cell markers Nanog, OCT4 and Sox2.
WANG Hua, CAI Hongbing, LI Shuwei, LI Wei, GAO Qian   +4 more
doaj   +1 more source

Aberrant Expression of High Mobility Group Box Protein 1 in the Idiopathic Inflammatory Myopathies

Frontiers in Cell and Developmental Biology, 2020
IntroductionHigh Mobility Group Box Protein 1 (HMGB1) is a DNA-binding protein that exerts inflammatory or pro-repair effects upon translocation from the nucleus.
Jessica Day, Jessica Day, Jessica Day, Sophia Otto, Sophia Otto, Kathy Cash, Preethi Eldi, Preethi Eldi, Pravin Hissaria, Pravin Hissaria, Susanna Proudman, Susanna Proudman, Vidya Limaye, Vidya Limaye, John D. Hayball, John D. Hayball, John D. Hayball   +16 more
doaj   +1 more source

HMGB1 mediates lipopolysaccharide-induced macrophage autophagy and pyroptosis

BMC Molecular and Cell Biology, 2023
Autophagy and pyroptosis of macrophages play important protective or detrimental roles in sepsis. However, the underlying mechanisms remain unclear.
Jiawei Shang, Feng Zhao, Yongmei Cao, Feng Ping, Wei Wang, Yingchuan Li   +5 more
doaj   +1 more source

Identification of HMGB1-Binding Components Using Affinity Column Chromatography [PDF]

, 2013
High Mobility Group B1 (HMGB1) is a 30 kDa protein widely expressed in mammalian cells. HMGB1 has a high content of charged amino acids and has a bipolar structure consisting of two highly positive amino terminal HMG-box domains and an acidic carboxy ...
Siljander, Pia, Pia Siljander, Heikki Rauval, Rouhiainen, Ari, Tukiainen, Helena, Ari Rouhiainen, Helena Tukiainen   +6 more
core   +1 more source

HMGB1: A novel Beclin 1-binding protein active in autophagy [PDF]

Autophagy, 2010
The autophagosome delivers damaged cytoplasmic constituents and proteins to the lysosome or to the extracellular space. Beclin 1, an essential: autophagic protein, is a BH3-only protein that binds Bcl-2 anti-apoptotic family members and has a critical role in the initiation of autophagy.
Rui, Kang, Kristen M, Livesey, Herbert J, Zeh, Michael T, Loze, Daolin, Tang   +4 more
openaire   +2 more sources