Measles virus causes immunogenic cell death in human melanoma [PDF]
, 2011 NoOncolytic viruses (OV) are promising treatments for cancer, with several currently undergoing testing in randomised clinical trials. Measles virus (MV) has not yet been tested in models of human melanoma.
Russell, S +44 more
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High-mobility group box protein 1 (HMGB1) expression in collagen-induced arthritis [PDF]
, 2011 The presence of cells expressing HMGB1 in the invading pannus of collagen-induced arthritis is shown. In this experiment, the section was stained for HMGB1 using affinity-purified polyclonal rabbit anti-HMGB1 antibodies (BD Pharmingen, San Diego, CA, USA)
David S Pisetsky (23495) +2 more
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HMGB1 related pathways in epilepsy [PDF]
, 2022 Epilepsy is one of the most common neurological illnesses, affecting an estimated 70 million individuals worldwide. A mechanistic approach to discovering crucial pathogenic brain abnormalities driving seizure onset, recurrence, and advancement is ...
Önal, C. +3 more
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Molecular Medicine, 2013 High mobility group box 1 (HMGB1) is a DNA-binding protein that possesses cytokinelike, proinflammatory properties when released extracellularly in the C23–C45 disulfide form. HMGB1 also plays a key role as a mediator of acute and chronic inflammation in
Sodam Kim +8 more
doaj +1 more source
Mini‐review: The nuclear protein HMGB1 as a proinflammatory mediator [PDF]
European Journal of Immunology, 2004 AbstractThe intranuclear architectural protein that is termed high mobility group box chromosomal protein 1 (HMGB1) was recently identified as a potent proinflammatory mediator when present extracellularly. HMGB1 has been demonstrated to be a long‐searched‐for nuclear danger signal passively released by necrotic, as opposed to apoptotic, cells that ...
Helena, Erlandsson Harris +1 more
openaire +2 more sources
High-mobility group chromosomal box protein 1 (HMGB1) expression at different time points after immunization [PDF]
, 2011 Copyright information:Taken from "Morphological characterization of intra-articular HMGB1 expression during the course of collagen-induced arthritis"http://arthritis-research.com/content/9/2/R35Arthritis Research & Therapy 2007;9(2):R35-R35.Published ...
Riikka Söderling (32046) +6 more
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Identification and characterization of the lamprey high-mobility group box 1 gene. [PDF]
PLoS ONE, 2012 High-mobility group box 1 (HMGB1), a highly conserved DNA-binding protein, plays an important role in maintaining nucleosome structures, transcription, and inflammation. We identified a homolog of HMGB1 in the Japanese lamprey (Lampetra japonica).
Yue Pang, Rong Xiao, Xin Liu, Qingwei Li
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High-mobility group chromosomal box protein 1 (HMGB1) mRNA is predominantly upregulated in areas of tissue destruction [PDF]
, 2011 Copyright information:Taken from "Morphological characterization of intra-articular HMGB1 expression during the course of collagen-induced arthritis"http://arthritis-research.com/content/9/2/R35Arthritis Research & Therapy 2007;9(2):R35-R35.Published ...
Riikka Söderling (32046) +6 more
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A substantial portion of cells expressing cytoplasmic high-mobility group chromosomal box protein 1 (HMGB1) are also ED1-positive [PDF]
, 2011 Copyright information:Taken from "Morphological characterization of intra-articular HMGB1 expression during the course of collagen-induced arthritis"http://arthritis-research.com/content/9/2/R35Arthritis Research & Therapy 2007;9(2):R35-R35.Published ...
Riikka Söderling (32046) +6 more
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High mobility group box 1 induced human lung myofibroblasts differentiation and enhanced migration by activation of MMP-9. [PDF]
PLoS ONE, 2015 High mobility group box 1 (HMGB1) is a nuclear protein that involves the binding with DNA and influences chromatin regulation and transcription. HMGB1 is also a cytokine that can activate monocytes and neutrophils involved in inflammation. In this study,
Chen-Chen Lee +4 more
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