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Recent Molecular Evolution of Human Metapneumovirus (HMPV): Subdivision of HMPV A2b Strains [PDF]

Microorganisms, 2020
Human metapneumovirus (HMPV) is a major etiological agent of acute respiratory infections in humans. HMPV has been circulating worldwide for more than six decades and is currently divided into five agreed-upon subtypes: A1, A2a, A2b, B1, and B2. Recently,
Naganori Nao, Miwako Saikusa, Ko Sato, Tsuyoshi Sekizuka, Shuzo Usuku, Nobuko Tanaka, Hidekazu Nishimura, Makoto Takeda   +7 more
doaj   +3 more sources

HMPV Virus Outbreak: First Review in Literature

Journal of Pharmacy and Bioallied Sciences
Human metapneumovirus (HMPV), a pathogen within the Pneumoviridae family, is a notable contributor to respiratory tract infections worldwide. Identified in 2001, HMPV predominantly affects young children, the elderly, and individuals with compromised ...
Sonia Dubey, Purushottam Lal, Nitin Kumar, Rahul Tiwari, Vinej Somaraj, Sailaja Sanda, Nirvi Sharma, Heena D. Tiwari   +7 more
doaj   +2 more sources

Cardio-Renal Diseases Are Independent Risk Factors of Severe Human Metapneumovirus Infection Among Patients Without Chronic Airway Diseases. [PDF]

J Med Virol
ABSTRACT Human metapneumovirus (hMPV) causes mild and self‐limiting disease in adults. However, the risk factors for serious adverse outcomes following hMPV infection in adult patients without preexisting chronic airway diseases remain poorly understood.
Kwok WC, Leung ISH, Wong CKE, Ho JCM, Lam DCL, Ip MSM, Ngai SM, To KKW, Yap DYH.   +8 more
europepmc   +2 more sources

Deep learning approach for automated hMPV classification

Scientific Reports
Human metapneumovirus (hMPV) is a significant cause of respiratory illness, particularly in children, elderly individuals, and immunocompromised patients. Despite its clinical relevance, hMPV poses diagnostic challenges due to its symptom similarity with
Sivarama Prasad Tera, Ravikumar Chinthaginjala, Irum Shahzadi, Priya Natha, Safia Obaidur Rab   +4 more
doaj   +3 more sources

hMPV Lineage Nomenclature and Heparin Binding [PDF]

Viruses, 2013
Human metapneumovirus (hMPV), first described in 2001 [1], is responsible for causing serious respiratory illness in young children, the elderly and immunocompromised patients. Four distinct lineages of hMPV have been identified with the original nomenclature for these subgroups (A1, A2, B1 and B2), reported by van den Hoogen et al.
David Gordon, John Williams, Gamaliel Muchondo, Tania Sadlon, Penelope Adamson, Sutthiwan Thammawat   +5 more
openaire   +3 more sources

Animal models for human Metapneumovirus (HMPV) infections [PDF]

Veterinary Research, 2007
Since its detection in 2001 the human Metapneumovirus (HMPV), a member of the Paramyxoviridae family, was observed to be a serious pathogen in human respiratory infections during childhood. Meanwhile, several animal models have been established to study the virus-host interactions and pathogenic effects.
Schildgen, Oliver, Simon, Arne, Williams, John   +2 more
openaire   +3 more sources

Host Components That Modulate the Disease Caused by hMPV [PDF]

Viruses, 2021
Human metapneumovirus (hMPV) is one of the main pathogens responsible for acute respiratory infections in children up to 5 years of age, contributing substantially to health burden. The worldwide economic and social impact of this virus is significant and must be addressed.
Nicolás M. S. Gálvez, Catalina A. Andrade, Gaspar A. Pacheco, Jorge A. Soto, Vicente Stranger, Thomas Rivera, Abel E. Vásquez, Alexis M. Kalergis   +7 more
openaire   +4 more sources

Human Metapneumovirus (HMPV) Binding and Infection Are Mediated by Interactions between the HMPV Fusion Protein and Heparan Sulfate [PDF]

Journal of Virology, 2012
ABSTRACT Human metapneumovirus (HMPV) is a major worldwide respiratory pathogen that causes acute upper and lower respiratory tract disease. The mechanism by which this virus recognizes and gains access to its target cell is still largely unknown.
Andres, Chang, Cyril, Masante, Ursula J, Buchholz, Rebecca Ellis, Dutch   +3 more
openaire   +2 more sources

Antibody recognition of the Pneumovirus fusion protein trimer interface.

PLoS Pathogens, 2020
Human metapneumovirus (hMPV) is a leading cause of viral respiratory infection in children, and can cause severe lower respiratory tract infection in infants, the elderly, and immunocompromised patients.
Jiachen Huang, Darren Diaz, Jarrod J Mousa   +2 more
doaj   +1 more source

Epidemiology and genotypic diversity of human metapneumovirus in paediatric patients with acute respiratory infection in Beijing, China

Virology Journal, 2021
Background Acute respiratory tract infections (ARTIs) causes high amounts of morbidity and mortality worldwide every year. Human metapneumovirus (HMPV) is a major pathogen of ARTIs in children.
Chao Wang, Tianli Wei, Fenlian Ma, Hao Wang, Jianqiang Guo, Aijun Chen, Yiman Huang, Zhiping Xie, Lishu Zheng   +8 more
doaj   +1 more source