Results 21 to 30 of about 6,905 (159)

Adjuvant effect of the human metapneumovirus (HMPV) matrix protein in HMPV subunit vaccines

open access: yesJournal of General Virology, 2015
The human metapneumovirus (HMPV) fusion (F) protein is the most immunodominant protein, yet subunit vaccines containing only this protein do not confer complete protection. The HMPV matrix (M) protein induces the maturation of antigen-presenting cells in vitro.
Aerts, Laetitia   +6 more
openaire   +2 more sources

Non-Coding RNAs and Their Role in Respiratory Syncytial Virus (RSV) and Human Metapneumovirus (hMPV) Infections

open access: yesViruses, 2020
Recent high-throughput sequencing revealed that only 2% of the transcribed human genome codes for proteins, while the majority of transcriptional products are non-coding RNAs (ncRNAs).
Wenzhe Wu   +4 more
doaj   +1 more source

Adult human metapneumonovirus (hMPV) pneumonia mimicking Legionnaire's disease [PDF]

open access: yesHeart & Lung, 2016
In adults hospitalized with viral pneumonias the main differential diagnostic consideration is influenza pneumonia. The respiratory viruses causing viral influenza like illnesses (ILIs), e.g., RSV may closely resemble influenza. Rarely, extrapulmonary findings of some ILIs may resemble Legionnaire's disease (LD), e.g., adenovirus, human parainfluenza ...
Cunha, Burke A.   +2 more
openaire   +2 more sources

Phylogenetic variability of Human Metapneumovirus in patients with acute respiratory infections in Cameroon, 2011–2014

open access: yesJournal of Infection and Public Health, 2020
Background: Identified in 2001, Human Metapneumovirus (HMPV) is a Pneumovirus associated with acute lower and upper respiratory infections in all age groups and especially in newborns, elderly and immunocompromised subjects. Data are still limited in sub-
Sebastien Kenmoe   +4 more
doaj   +1 more source

Global Extension and Predominance of Human Metapneumovirus A2 Genotype with Partial G Gene Duplication

open access: yesViruses, 2022
Human metapneumovirus (HMPV) is an important respiratory pathogen and is divided in two main groups (A and B). HMPV strains with partial duplications (111-nt and 180-nt duplication) of the G gene have been reported in recent years.
Juan Carlos Muñoz-Escalante   +3 more
doaj   +1 more source

Comparing Human Metapneumovirus and Respiratory Syncytial Virus: Viral Co-Detections, Genotypes and Risk Factors for Severe Disease.

open access: yesPLoS ONE, 2017
BackgroundIt is unclarified as to whether viral co-detection and human metapneumovirus (HMPV) genotypes relate to clinical manifestations in children with HMPV and lower respiratory tract infection (LRTI), and if the clinical course and risk factors for ...
Nina Moe   +7 more
doaj   +1 more source

Human Metapneumovirus (hMPV) Infection and MPV467 Treatment in Immunocompromised Cotton Rats Sigmodon hispidus

open access: yesViruses, 2023
Human metapneumovirus (hMPV) is an important cause of respiratory disease in immunocompromised individuals, yet hMPV infection has not been modeled before in immunocompromised animals. In this work, cotton rats S.
Kevin C. Yim   +4 more
doaj   +1 more source

Human Metapneumovirus Circulation and Seasonality on a Global Scale, 2016-2025: Changes in Patterns and Epidemic Timing in the Pre- Versus Post-COVID-19 Era. [PDF]

open access: yesInfluenza Other Respir Viruses
ABSTRACT Background Human metapneumovirus (hMPV) circulates globally, yet its seasonal dynamics remain incompletely defined. Here, we describe the global timing, amplitude and duration of hMPV outbreaks, comparing the pre‐ versus post‐COVID‐19 periods. Methods Surveillance data for hMPV were retrieved from WHO FluNet from Week 1/2016 until Week 26/2025.
Castellana E   +6 more
europepmc   +2 more sources

Consensus and variations in cell line specificity among human metapneumovirus strains.

open access: yesPLoS ONE, 2019
Human metapneumovirus (HMPV) has been a notable etiological agent of acute respiratory infection in humans, but it was not discovered until 2001, because HMPV replicates only in a limited number of cell lines and the cytopathic effect (CPE) is often mild.
Naganori Nao   +13 more
doaj   +1 more source

Human Metapneumovirus in Turkey Poults

open access: yesEmerging Infectious Diseases, 2006
This study was conducted to reexamine the hypothesis that human metapneumovirus (hMPV) will not infect turkeys. Six groups of 2-week-old turkeys (20 per group) were inoculated oculonasally with 1 of the following: noninfected cell suspension; hMPV ...
Binu T. Velayudhan   +5 more
doaj   +1 more source

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