Results 31 to 40 of about 6,905 (159)

Whole genome characteristics of respiratory human metapneumovirus isolated in Ningxia Hui Autonomous Region

Zhongguo gonggong weisheng, 2023
ObjectiveTo analyze genetic characteristics of human metapneumovirus (hMPV) strains isolated in Ningxia Hui Autonomous Region (Ningxia) for providing relevant data to construct hMPV genome database in China.
Xinning WANG, Yanyan SU, Zhonglan WU, Min CAO, Longshan LI, Jianxin PEI, Xueping MA   +6 more
doaj   +1 more source

A decade of human metapneumovirus in hospitalized children with acute respiratory infection: molecular epidemiology in central Vietnam, 2007–2017

Scientific Reports, 2023
Human metapneumovirus (hMPV) can cause severe acute respiratory infection (ARI). We aimed to clarify the clinical and molecular epidemiological features of hMPV. We conducted an ARI surveillance targeting hospitalized children aged 1 month to 14 years in
Hirono Otomaru, Hien Anh Thi Nguyen, Hien Minh Vo, Michiko Toizumi, Minh Nhat Le, Katsumi Mizuta, Hiroyuki Moriuchi, Minh Xuan Bui, Duc Anh Dang, Lay-Myint Yoshida   +9 more
doaj   +1 more source

The Prevalence and Genetic Characterization of Human Metapneumovirus in Bulgaria, 2016–2019

Intervirology, 2021
Introduction: We investigated the prevalence of human metapneumovirus (hMPV) among patients with acute respiratory infections in Bulgaria, and performed genetic characterization of the F gene of these strains. Methods: Nasopharyngeal swabs collected from
Neli S. Korsun, Svetla G. Angelova, Ivelina T. Trifonova, Silvia E. Voleva, Iliana G. Grigorova, Iren S. Tzotcheva, Sirma D. Mileva, Penka I. Perenovska   +7 more
doaj   +1 more source

HMPV-TherResDB: Comprehensive human metapneumovirus (HMPV) database for sequence-structure annotations, vaccine resources, and therapeutics research. [PDF]

Virus Res
Khan A, Mohammad A, Alshabrmi FM, Alatawi EA, Junaid M, Agouni A.   +5 more
europepmc   +2 more sources

Human Metapneumovirus Phosphoprotein Independently Drives Phase Separation and Recruits Nucleoprotein to Liquid-Like Bodies

mBio, 2022
Human metapneumovirus (HMPV) inclusion bodies (IBs) are dynamic structures required for efficient viral replication and transcription. The minimum components needed to form IB-like structures in cells are the nucleoprotein (N) and the tetrameric ...
Kerri Beth Boggs, Kearstin Edmonds, Nicolas Cifuentes-Munoz, Farah El Najjar, Conny Ossandón, McKenna Roe, Chao Wu, Carole L. Moncman, Trevor P. Creamer, Gaya K. Amarasinghe, Daisy W. Leung, Rebecca Ellis Dutch   +11 more
doaj   +1 more source

Diversity in Glycosaminoglycan Binding Amongst hMPV G Protein Lineages [PDF]

Viruses, 2012
We have previously shown that hMPV G protein (B2 lineage) interacts with cellular glycosaminoglycans (GAGs). In this study we examined subtypes A1, A2 and B1 for this interaction. GAG-dependent infectivity of available hMPV strains was demonstrated using GAG-deficient cells and heparin competition.
Adamson, Penelope, Thammawat, Sutthiwan, Muchondo, Gamaliel, Sadlon, Tania, Gordon, David   +4 more
openaire   +3 more sources

Respiratory Syncytial Virus Under the Lens of Structure: From Prefusion Stabilization to Next‐Generation Immunotherapies

iNew Medicine, EarlyView.
This illustration integrates key concepts covered in the review, including high‐risk populations, viral structure, host entry factors, the replication cycle, and licensed antibody‐based prevention strategies. ABSTRACT Respiratory syncytial virus (RSV) is a negative‐sense RNA virus belonging to the genus Orthopneumovirus within the family Pneumoviridae.
Zekai Cheng, Qianqian Wang, Jiachen Zhang, Sandra Chiu   +3 more
wiley   +1 more source

Human metapneumovirus: insights from a ten-year molecular and epidemiological analysis in Germany. [PDF]

PLoS ONE, 2014
Human metapneumovirus (HMPV) is a cause of respiratory tract illness at all ages. In this study the epidemiological and molecular diversity among patients of different ages was investigated. Between 2000-2001 and 2009-2010, HMPV was detected in 3% (138/4,
Janine Reiche, Sonja Jacobsen, Katrin Neubauer, Susi Hafemann, Andreas Nitsche, Jeanette Milde, Thorsten Wolff, Brunhilde Schweiger   +7 more
doaj   +1 more source

Evidence‐based guideline for clinical practice in the diagnosis, treatment, management, and prevention of recurrent wheezing in infants and toddlers in China

Pediatric Investigation, EarlyView.
ABSTRACT Wheezing is a common respiratory symptom in infants and toddlers, and recurrent wheezing is a significant respiratory disorder affecting this age group. Given the multifactorial etiology of recurrent wheezing, clinical practice lacks standardized diagnostic and therapeutic protocols. Recent years have witnessed substantial progress in clinical
Committee of Pediatrics, China Medical Education Association, Cooperative Group of Asthma, the Subspecialty Group of Respiratory, the Society of Pediatrics, Chinese Medical Association, Pediatric Respiratory Work Committee, Society of Pulmonologists, Chinese Medical Doctor Association, Committee of Pediatrics, Chinese Research Hospital Association, Pediatric Professional Committee of the Chinese Non‐public Medical Institutions Association, Professional Committee of Children's Health and Pharmaceutical Research, China Association of Traditional Chinese Medicine, Children's Safe Medication Branch of China News of Drug Information Association, Pediatric Expert Committee of China Primary Health Care Foundation, China International Medical Foundation   +16 more
wiley   +1 more source

Protective efficacy of a novel recombinant influenza virus carrying partial human metapneumovirus F protein epitopes

Virulence
Human metapneumovirus (HMPV) is a leading cause of acute respiratory tract infections in infants and children. Currently, no approved HMPV vaccine is available.
Fang Sun, Guanglin Lei, Chongyu Tian, Zhifang Bai, Changqing Bai, Yufeng Li, Zhuoya Deng, Hao Yang, Cong Li, Zhongpeng Zhao, Yan Niu, Penghui Yang   +11 more
doaj   +1 more source