Results 71 to 80 of about 6,905 (159)

A Sendai virus recombinant vaccine expressing a gene for truncated human metapneumovirus (hMPV) fusion protein protects cotton rats from hMPV challenge

Virology, 2017
Human metapneumovirus (hMPV) infections pose a serious health risk to young children, particularly in cases of premature birth. No licensed vaccine exists and there is no standard treatment for hMPV infections apart from supportive hospital care. We describe the production of a Sendai virus (SeV) recombinant that carries a gene for a truncated hMPV ...
Charles J, Russell, Bart G, Jones, Robert E, Sealy, Sherri L, Surman, John N, Mason, Randall T, Hayden, Ralph A, Tripp, Toru, Takimoto, Julia L, Hurwitz   +8 more
openaire   +2 more sources

Clinical characteristics and risk factors of severe bocavirus‐positive pneumonia in children and a literature review

Pediatric Discovery, Volume 3, Issue 4, December 2025.
The study explored the clinical characteristics and risk factors of HBoV‐positive severe pneumonia in children. These findings indicate that HBoV can be identified in respiratory samples from children with severe pneumonia, denoting its role as a viral pathogen in hospitalized children with this condition.
Jing Liao, Zhongying Yang, Yu He, Jianhua Wei, Luo Ren, Enmei Liu, Na Zang   +6 more
wiley   +1 more source

Human Metapneumovirus Attachment Protein Contributes to Neutrophil Recruitment into the Airways of Infected Mice

Viruses, 2017
Human Metapneumovirus (HMPV) is a leading respiratory pathogen that causes lower respiratory tract infections worldwide. Acute HMPV infection induces an exacerbated inflammatory neutrophilic response leading to bronchiolitis and pneumonia.
Nagarjuna R. Cheemarla, Antonieta Guerrero-Plata   +1 more
doaj   +1 more source

GLAMPING—A POST-PANDEMIC TOURISM MODEL: FROM THEORETICAL DEFINITION TO SPATIO-TEMPORAL MAPPING IN THE SOUTH-WEST OLTENIA REGION, ROMANIA [PDF]

Analele Universităţii Constantin Brâncuşi din Târgu Jiu : Seria Economie
Glamping, which brings together the comfort of a luxury hotel and natural environments, represents a tourism model enabling the relaunch of post-COVID-19 tourism, thus contributing to the sustainable development of tourism in Oltenia.
DRĂGULEASA IONUȚ-ADRIAN, NIȚĂ AMALIA, MAZILU MIRELA, BĂNUȚ MARIA MĂDĂLINA , BĂBĂȚ ANDREI-FLORIN   +4 more
doaj  

A neutralizing single-domain antibody that targets the trimer interface of the human metapneumovirus fusion protein

mBio
Human metapneumovirus (hMPV) is a leading cause of viral lower respiratory tract disease in children and adults. The hMPV fusion protein F is a trimeric class I fusion protein that is initially synthesized as a precursor (F0) and requires proteolytic ...
Marlies Ballegeer, Revina C. van Scherpenzeel, Teresa Delgado, Maria Iglesias-Caballero, Blanca García Barreno, Shubham Pandey, Scott A. Rush, Joost A. Kolkman, Vicente Mas, Jason S. McLellan, Xavier Saelens   +10 more
doaj   +1 more source

Human Metapneumovirus Infection among Children Hospitalized with Acute Respiratory Illness

Emerging Infectious Diseases, 2004
Recent studies have associated human Metapneumovirus (HMPV) infection in children with respiratory disease of similar severity as respiratory syncytial virus (RSV) infection.
James A. Mullins, Dean D. Erdman, Geoffrey A. Weinberg, Kathryn M. Edwards, Caroline B. Hall, Frances J. Walker, Marika Iwane, Larry J. Anderson   +7 more
doaj   +1 more source

Probenecid Inhibits Human Metapneumovirus (HMPV) Replication In Vitro and in BALB/c Mice

Viruses
Human metapneumovirus (HMPV) is an important cause of acute respiratory tract infection and causes significant morbidity and mortality. There is no specific antiviral drug to treat HMPV or vaccine to prevent HMPV.
Harrison C. Bergeron, Jackelyn Crabtree, Tamas Nagy, David E. Martin, Ralph A. Tripp   +4 more
doaj   +1 more source

Human Metapneumovirus and Severity of Respiratory Syncytial Virus Disease

Emerging Infectious Diseases, 2004
We screened 23 children with severe respiratory syncytial virus (RSV) disease and 23 children with mild RSV disease for human metapneumovirus (HMPV). Although HMPV was circulating in Connecticut, none of the 46 RSV-infected patients tested positive for ...
Isaac Lazar, Carla Weibel, James Dziura, David Ferguson, Marie L. Landry, Jeffrey S. Kahn   +5 more
doaj   +1 more source

Large-scale seroprevalence analysis of human metapneumovirus and human respiratory syncytial virus infections in Beijing, China

Virology Journal, 2011
Background Human metapneumovirus (hMPV), a recently identified virus, causes acute respiratory tract infections (ARTIs) in infants and children. However, studies on the seroepidemeology of hMPV are very limited in China.
Wu Jiang, Wu Chao, Guo Li, Gonzalez Richard, Lu Guilan, Vernet Guy, Paranhos-Baccalà Gláucia, Wang Jianwei, Hung Tao   +8 more
doaj   +1 more source

Human metapneumovirus (HMPV): A brief overview

Svāsthya: Trends in General Medicine and Public Health
Human metapneumovirus (HMPV), discovered in 2001, is a significant respiratory pathogen in the Paramyxoviridae family that is responsible for substantial global morbidity and mortality. Despite its clinical impact, HMPV remains underdiagnosed and lacks specific treatments and vaccines.
openaire   +1 more source