Characterization of genotype-specific epitopes of the HN protein of mumps virus.
The SBL-1 strain of mumps virus, grouping with genotype A on the basis of the small hydrophobic protein gene sequence, was grown in the presence of three different monoclonal antibodies. The monoclonal antibodies were directed against the haemagglutinin-neuraminidase (HN) protein and they inhibited haemagglutinating activity and infectivity of the ...
C, Orvell +3 more
openaire +2 more sources
Expression of Haemagglutinin-Neuraminidase Envelope Protein of Newcastle Disease Virus Strain Af2240 in Centella Asiatica (Pegaga) Embryogenic Calli Through Optimized Particle Bombardment Method [PDF]
Centella asiatica is a locally important medicinal plant. It is non-toxic, high in medicinal values, and can serve as a good candidate for genetic manipulation. However, to date no transformation protocol has been developed to fully utilize the potential
Lai, Kok Song
core
Unexpected transformation of dissolved phenols to toxic dicarbonyls by hydroxyl radicals and UV light. [PDF]
Water treatment systems frequently use strong oxidants or UV light to degrade chemicals that pose human health risks. Unfortunately, these treatments can result in the unintended transformation of organic contaminants into toxic products.
Ford, Breanna +3 more
core +1 more source
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
To better understand the phylogenomics of the hemagglutinin-neuraminidase (HN) gene and HN protein in human parainfluenza virus type 4 (HPIV4), we performed phylogenomic analyses using various bioinformatics methods.
Kanako Otani +8 more
doaj +1 more source
Clinical, histological, and serological predictors of renal function loss in lupus nephritis.
Objective Kidney survival is the ultimate goal in lupus nephritis (LN) management, but long‐term predictors remain inadequately studied, requiring long‐term follow‐up. This study aimed to identify baseline and early longitudinal predictors of kidney survival in the Accelerating Medicines Partnership LN longitudinal cohort.
Shangzhu Zhang +21 more
wiley +1 more source
A Single Molecule Study of Gene Silencing by HNS Protein DNA Interactions [PDF]
Histone-like nucleoid structuring (H-NS) proteins are an important prokaryotic protein responsible for organizing and compacting chromosomal DNA. Recently, it was found that H-NS can identify foreign genes acquired by horizontal gene transfer (HGT), based on AT content, and selectively silence these genes.
Wang, Haowei +3 more
openaire +1 more source
Thermostability of the Recombinant Haemagglutinin-Neuraminidase Glycoproteins of Newcastle Disease Virus [PDF]
The haemagglutinin-neuraminidase (HN) glycoprotein of Newcastle disease virus (NDV) is of primary importance in inducing virus-neutralizing antibodies against viral infection in chicken and has been used in the development of many vaccines.
Tang, Yik Kiong
core
The context-dependence of mutations: a linkage of formalisms
Defining the extent of epistasis - the non-independence of the effects of mutations - is essential for understanding the relationship of genotype, phenotype, and fitness in biological systems.
Krishna, Vinod +2 more
core +3 more sources
How round is a protein? Exploring protein structures for globularity using conformal mapping. [PDF]
We present a new algorithm that automatically computes a measure of the geometric difference between the surface of a protein and a round sphere. The algorithm takes as input two triangulated genus zero surfaces representing the protein and the round ...
Hass, Joel, Koehl, Patrice
core +2 more sources

