Results 1 to 10 of about 16,332 (165)

Different Origins of Newcastle Disease Virus Hemagglutinin-Neuraminidase Protein Modulate the Replication Efficiency and Pathogenicity of the Virus [PDF]

Frontiers in Microbiology, 2017
To investigate the exact effects of different origins of Newcastle disease virus (NDV) hemagglutinin-neuraminidase (HN) protein to the biological characteristics of the virus, we systematically studied the correlation between the HN protein and NDV ...
Jinlong Cheng, Ying-Chao Ren, Guozhong Zhang   +2 more
exaly   +4 more sources

Screening and mechanistic study of key sites of the hemagglutinin-neuraminidase protein related to the virulence of Newcastle disease virus [PDF]

Poultry Science, 2020
Newcastle disease is a kind of avian infectious disease caused by Newcastle disease virus (NDV). The virulence of NDV is dependent mainly on the fusion (F) protein and hemagglutinin-neuraminidase (HN) protein.
Fathalrhman Eisa Addoma Adam, Xinglong Wang, Zengqi Yang   +2 more
exaly   +4 more sources

Direct interaction of the molecular chaperone GRP78/BiP with the Newcastle disease virus hemagglutinin-neuraminidase protein plays a vital role in viral attachment to and infection of culture cells [PDF]

Frontiers in Immunology, 2023
IntroductionGlucose Regulated Proteins/Binding protein (GRP78/Bip), a representative molecular chaperone, effectively influences and actively participates in the replication processes of many viruses.
Yadi Lv, Ding Xiang Liu, Ruiai Chen
exaly   +4 more sources

Expression and characterization of hemagglutinin-neuraminidase protein from Newcastle disease virus in Bacillus subtilis WB800. [PDF]

J Genet Eng Biotechnol, 2022
Background Newcastle disease virus (NDV) belongs to the genus Avaluvirus and Paramyxoviridae family, and it can cause acute, highly contagious Newcastle disease in poultry.
Shafaati M, Ghorbani M, Mahmoodi M, Ebadi M, Jalalirad R.   +4 more
europepmc   +4 more sources

Novel Reassortant H5N2 Highly Pathogenic Avian Influenza Viruses from Backyard Poultry in Mexico. [PDF]

Viruses
Highly pathogenic influenza A viruses of the H5 subtype continue to diversify worldwide through mutation and genetic reassortment, generating novel variants with unpredictable consequences under the One Health approach.
Solís-Hernández M, Orta-Pineda G, Alcazar-Ramiro CJ, Velázquez-Vázquez MA, Garnica-Rivera C, Rocha-Martínez MK, Carrillo-Guzmán N, Tetla-Zapotitla IE, Tiburcio-Sánchez I, Piña-Trevilla HJ, Liljehult-Fuentes FJ, García-López A.   +11 more
europepmc   +2 more sources

A primary oseltamivir-resistant mutation in influenza hemagglutinin and its implications for antiviral resistance surveillance. [PDF]

Nat Commun
Oseltamivir, a neuraminidase (NA) inhibitor, is currently the most widely used antiviral drug for influenza worldwide. The emergence of primary oseltamivir-resistant mutations in NA protein of seasonally circulating viruses has been extensively monitored
Zhang L, Shao Y, Zou X, Cui Y, Ding S, Chen Y, Wu Q, Mu S, Li X, Yang Q, Cao B, Deng T.   +11 more
europepmc   +2 more sources

Human parainfluenza virus 3 fusion protein cleavage: a key determinant of infection and spread. [PDF]

J Virol
Human parainfluenza virus 3 (HPIV3) entry into target cells depends on a viral fusion complex composed of hemagglutinin-neuraminidase (HN) and fusion protein (F).
Stearns K, Marcink T, Pawlack E, Sobolik EB, Porotto M, Greninger AL, Nieweisk S, Moscona A.   +7 more
europepmc   +2 more sources

Structure-function analysis of two variants of mumps virus hemagglutinin-neuraminidase protein [PDF]

Brazilian Journal of Infectious Diseases, 2009
A point mutation from guanine (G) to adenine (A) at nucleotide position 1081 in the hemagglutinin-neuraminidase (HN) gene has been associated with neurovirulence of Urabe AM9 mumps virus vaccine. This mutation corresponds to a glutamic acid (E) to lysine
Gerardo Santos-López, Thomas Scior, María del Tránsito Borraz-Argüello, Verónica Vallejo-Ruiz, Irma Herrera-Camacho, José Tapia-Ramírez, Julio Reyes-Leyva   +6 more
doaj   +4 more sources

Evidence that Receptor Destruction by the Sendai Virus Hemagglutinin-Neuraminidase Protein Is Responsible for Homologous Interference. [PDF]

J Virol, 2016
ABSTRACT Receptor destruction has been considered one of the mechanisms of homologous Sendai virus (SeV) interference. However, direct evidence of receptor destruction upon virus infection and its relevance to interference is missing. To investigate a precise mechanism of homologous interference, we established SeV persistently infected cells.
Goto H, Ohta K, Matsumoto Y, Yumine N, Nishio M.   +4 more
europepmc   +4 more sources

Hemagglutinin-neuraminidase Sequence and Phylogenetic Analysis of Two Newcastle Disease Virus Isolated from Chickens in Iran [PDF]

Archives of Razi Institute, 2021
Newcastle disease is a highly contagious viral infection affecting many species of birds that can spread fast between poultry houses and cause a heavy economic burden on the poultry industry all around the world.
M. H Kiani, M. H Bozorgmehrifard, H Hosseini, S Charkhkar, A Ghalyanchilangeroudi   +4 more
doaj   +1 more source