Results 41 to 50 of about 16,332 (165)

Biological Significance of Dual Mutations A494D and E495K of the Genotype III Newcastle Disease Virus Hemagglutinin-Neuraminidase In Vitro and In Vivo

Viruses, 2022
As a multifunctional protein, the hemagglutinin-neuraminidase (HN) protein of Newcastle disease virus (NDV) is involved in various biological functions.
Xiaolong Lu, Tiansong Zhan, Kaituo Liu, Yu Chen, Zenglei Hu, Jiao Hu, Min Gu, Shunlin Hu, Xiaoquan Wang, Xiaowen Liu, Xiufan Liu   +10 more
doaj   +1 more source

Roles for the Cytoplasmic Tails of the Fusion and Hemagglutinin-Neuraminidase Proteins in Budding of the Paramyxovirus Simian Virus 5 [PDF]

Journal of Virology, 2002
ABSTRACTThe efficient release of many enveloped viruses from cells involves the coalescence of viral components at sites of budding on the plasma membrane of infected cells. This coalescence is believed to require interactions between the cytoplasmic tails of surface glycoproteins and the matrix (M) protein.
David L, Waning, Anthony P, Schmitt, George P, Leser, Robert A, Lamb   +3 more
openaire   +2 more sources

Antigenic Structure, Function, and Evolution of the Hemagglutinin‐Neuraminidase Protein of Human Parainfluenza Virus Type 1 [PDF]

The Journal of Infectious Diseases, 1997
Twenty-two monoclonal antibodies directed to the hemagglutinin-neuraminidase protein of human parainfluenza virus type 1 (HPIV-1) were used in competition assays to create an antigenic map of neutralization sites. Eighty-seven clinical strains isolated over 35 years from multiple geographic regions were reacted in ELISA, hemagglutinin-inhibition, and ...
K J, Henrickson, L L, Savatski
openaire   +2 more sources

Hemagglutinating and fusogenic activities of Newcastle disease virus: studies on receptor binding specificity and pH-induced conformational changes

Memorias do Instituto Oswaldo Cruz, 1995
Vaccinal and wild strains of Newcastle Disease virus (NDV) were analyzed for cell receptor binding and fusogenic biological properties associated with their HN (hemagglutinin-neuraminidase) and F (fusion protein) surface structures respectively.
E. S. S. Couceiro, J. N. S. S. Couceiro, M. C. Cabral   +2 more
doaj   +1 more source

Lymphoid‐Tissue‐on‐Chip Recapitulates Human Antibody Responses In Vitro

Advanced Science, EarlyView.
The presented lymphoid‐tissue‐on‐chip system allows culture of primary human tonsil cells at organotypic high density under perfusion for up to 4 weeks, emulates immune response to soluble vaccines and vaccination via peripheral antigen‐presenting cells and represents a useful tool to assess cellular interactions during homeostasis, immune responses ...
Claudia Teufel, Anna‐Sophie Schlemmer, Andrea W. Eiken, Zachary W. Wagoner, Dennis Vöhringer, Lena Christ, Alex Dulovic, Patrick Marsall, Madeleine Fandrich, Eduardo J. S. Brás, Julia Marzi, Friederike Bärhold, Julia Philipp, Sven Becker, Lisa E. Wagar, Peter Loskill   +15 more
wiley   +1 more source

Isolation and characteristic analysis of a novel strain H7N9 of avian influenza virus A from a patient with influenza-like symptoms in China

International Journal of Infectious Diseases, 2015
A novel H7N9 virus (A/Changsha/1/2013(H7N9)) identified through routine examination in the influenza network laboratory was analyzed retrospectively.
Faming Chen, Junhua Li, Biancheng Sun, Hong Zhang, Rusheng Zhang, Jie Yuan, Xinhua Ou, Wen Ye, Jingfang Chen, Yunzhi Liu, Yiwei Huang   +10 more
doaj   +1 more source

Toward Predicting Pandemic Potential: A Comparative Analysis of Virus‐Host Interactions Between Diverse Influenza A Viruses and the Human Innate Immune System

PROTEOMICS, EarlyView.
ABSTRACT Zoonotic infections caused by influenza A viruses (IAVs) of animal origin are a major public health concern, as they may represent the initial step toward the emergence of a pandemic strain. The host range of IAVs is shaped by species‐specific virus‐host interactions, and several host barriers have been identified that restrict the adaptation ...
Antoine Gerodez, Melanie Dos Santos, Mikaël Attia, Killian De Geest, Ibrahim Hamid, Rodrigue Tesse, Ilham Fdillate, Marc Boschmans, Steven Van Borm, Mieke Steensels, Benedicte Lambrecht, Lionel Tafforeau, Caroline Demeret, Cyril Barbezange   +13 more
wiley   +1 more source

Mutations in the Ectodomain of Newcastle Disease Virus Fusion Protein Confer a Hemagglutinin-Neuraminidase-Independent Phenotype [PDF]

Journal of Virology, 2010
ABSTRACT The entry of enveloped viruses into host cells is preceded by membrane fusion, which in paramyxoviruses is triggered by the fusion (F) protein. Refolding of the F protein from a metastable conformation to a highly stable postfusion form is critical for the promotion of fusion, although the mechanism is still not well understood. Here
Ayllón Barasoain, Juan, Villar, Enrique, Muñoz Barroso, Isabel   +2 more
openaire   +4 more sources

Feathers and flu: identifying data gaps in avian influenza host dynamics to prioritize wildlife conservation Plumas y gripe: identificación de datos faltantes en la dinámica de hospedadores de la influenza aviar para priorizar la conservación de la vida silvestre

Wildlife Monographs, EarlyView.
We describe the host response continuum for highly pathogenic avian influenza viruses (HPAIV), including the continuum of host responses to HPAIV infection and exposure based on the primary axis of host competence, ability to infect other hosts, and host vulnerability.
Johanna A. Harvey, Matthew Gonnerman, Shenglai Yin, Cody M. Kent, Joshua Cullen, Jeffery D. Sullivan, Jonathan B. Dain, Nichola J. Hill, Diann J. Prosser, Jennifer M. Mullinax   +9 more
wiley   +1 more source

Hemagglutinin-esterase-fusion (HEF) protein of influenza C virus

Protein & Cell, 2015
Influenza C virus, a member of the Orthomyxoviridae family, causes flu-like disease but typically only with mild symptoms. Humans are the main reservoir of the virus, but it also infects pigs and dogs.
Mingyang Wang, Michael Veit
doaj   +1 more source