Results 51 to 60 of about 16,332 (165)

Navigating the Future of Respiratory Infections: Key Insights From International Congress in Singapore, 17–20 September 2025

Influenza and Other Respiratory Viruses, Volume 20, Issue 7, July 2026.
ABSTRACT Background The 8th International Society for Respiratory Viruses (ISRV) Antiviral Group Conference, held jointly with the 3rd International Meeting on Respiratory Pathogens in Singapore (17–20 September 2025), examined evolving approaches to prevention and management of respiratory infections.
Narmadha Morvil, Wilson Guo Wei Goh, Charlotte Zheng, Stephanie Sutjipto, Dorothy Hui Lin Ng, Maria Zambon   +5 more
wiley   +1 more source

Biological Significance of the Second Receptor Binding Site of Newcastle Disease Virus Hemagglutinin-Neuraminidase Protein [PDF]

Journal of Virology, 2004
ABSTRACT The paramyxovirus hemagglutinin-neuraminidase (HN) is a multifunctional protein responsible for attachment to receptors containing sialic acid, neuraminidase (NA) activity, and the promotion of membrane fusion, which is induced by the fusion protein. Analysis of the three-dimensional structure of Newcastle disease virus (
Tatiana L, Bousse, Garry, Taylor, Sateesh, Krishnamurthy, Allen, Portner, Siba K, Samal, Toru, Takimoto   +5 more
openaire   +2 more sources

Molecular Characterization of Hemagglutinin-Neuraminidase Protein Virus Newcastle disease (ND) in Surabaya during 2003 and 2016

Jurnal Medik Veteriner, 2021
This study aimed to determine the mutation of amino acid, nucleotide homology, phylogenetic tree, epitope prediction of Hemagglutinin-Neuraminidase protein Newcastle Disease (ND) Virus isolated from traditional market around Surabaya.
Innah Wulandari, Jola Rahmahani, Indah Rahmawati, Nurvita Putih, Aisyah Azahro, Kusnoto Kusnoto, Rahayu Ernawati, Fedik Abdul Rantam   +7 more
doaj   +1 more source

Immunogenicity of a Multi‐Epitope Influenza Composite Peptide Vaccine Targeting Human, Swine, and Avian Viruses: Advancing Pandemic Preparedness

Influenza and Other Respiratory Viruses, Volume 20, Issue 7, July 2026.
ABSTRACT Background The emergence of novel reassortant influenza A virus strains and zoonotic transmission to the human population is a critical factor in the development of a global pandemic, as exemplified by the 2009 swine flu pandemic and the ongoing threat of an H5N1 avian flu pandemic.
Nimisha Rikhi, Clara J. Sei, Kellie A. Fraser, Kevin Muema, Aba Assiaw‐Dufu, Richard F. Schuman, Gerald W. Fischer   +6 more
wiley   +1 more source

Introduction of Cysteines in the Stalk Domain of Recombinant Influenza Virus N1 Neuraminidase Enhances Protein Stability and Immunogenicity in Mice

Vaccines, 2021
Influenza virus surface glycoproteins represent the main targets of the immune system during infection and vaccination. Current influenza virus vaccines rely mostly on the hemagglutinin, requiring a close match between the vaccine and circulating strains.
Shirin Strohmeier, Juan Manuel Carreño, Ruhi Nichalle Brito, Florian Krammer   +3 more
doaj   +1 more source

Enhanced Human Antigen‐Specific B Cell Responses Using In Vitro 3D Tonsil Cultures Containing Stromal Cells

Advanced Healthcare Materials, Volume 15, Issue 22, 12 June 2026.
We developed a fully human 3D tonsil cell culture system incorporating supportive stromal cells that better sustains and activates immune cells than conventional methods. The model generates stronger, more targeted antibody responses to viral antigens and vaccines, providing a physiologically relevant and entirely human platform for studying immune ...
Maaike V. J. Braham, Marlon de Gast, Liubov Babii, Sabine Kruijer, Theo M. Bestebroer, Mathilde Richard, Mathieu Claireaux, S. Marieke van Ham, Jelle de Wit, Cécile A. C. M. van Els, Anja ten Brinke, Marit J. van Gils   +11 more
wiley   +1 more source

Biological activities of monoclonal antibodies to the hemagglutinin-neuraminidase (HN) protein of newcastle disease virus.

The Japanese Journal of Veterinary Science, 1986
Eleven monoclonal antibodies to the HN protein of NDV strain Sato were established and used to elucidate the functions and antigenic structure of the HN molecule. Seven of these antibodies showed various patterns of inhibition against biological functions of the virus; whereas, 4 antibodies did not inhibit any viral function tested.
ABENES, Gerardo B., KIDA, Hiroshi, YANAGAWA, Ryo   +2 more
openaire   +3 more sources

The peculiar characteristics and advancement in diagnostic methodologies of influenza A virus

Frontiers in Microbiology
Influenza A virus (IAV) is a significant public health concern, causing seasonal outbreaks and occasional pandemics. These outbreaks result from changes in the virus’s surface proteins which include hemagglutinin and neuraminidase.
Muhammad Asif Raza, Muhammad Asif Raza, Muhammad Awais Ashraf, Muhammad Awais Ashraf, Muhammad Nabeel Amjad, Muhammad Nabeel Amjad, Ghayyas Ud Din, Ghayyas Ud Din, Bei Shen, Yihong Hu, Yihong Hu   +10 more
doaj   +1 more source

RNF213 Is an Interferon‐Stimulated Gene That Targets Influenza A Virus NP and Activates MDA5 to Restrict Infection

Advanced Science, Volume 13, Issue 31, 4 June 2026.
RNF213 is characterized as a dual‐functional antiviral effector. It directly mediates the degradation of the influenza A virus nucleoprotein (NP) while simultaneously activating the MDA5‐mediated innate immune signaling pathway. This coordinated response establishes a powerful host defense system against viral infection. ABSTRACT Influenza A virus (IAV)
Haoning Li, Yuying Zhang, Jingjing Wang, Qianqian Zhang, Hailiang Sun, Fanhua Wei   +5 more
wiley   +1 more source

Structural and functional characterization of peste des petits ruminants virus coded hemagglutinin protein using various in-silico approaches

Frontiers in Microbiology
Peste des petits ruminants (PPR), a disease of socioeconomic importance has been a serious threat to small ruminants. The causative agent of this disease is PPR virus (PPRV) which belongs to the genus Morbillivirus.
Sharad Kumar Gaur, Yash Chaudhary, Juhi Jain, Rashmi Singh, Rajeev Kaul   +4 more
doaj   +1 more source