Results 61 to 70 of about 2,375 (233)

Effects of vitamin B-12 supplementation on neurologic and cognitive function in older people: a randomized controlled trial. [PDF]

, 2015
BACKGROUND: Moderate vitamin B-12 deficiency is relatively common in older people. However, there is little robust evidence on the effect of vitamin B-12 supplementation on neurologic and cognitive outcomes in later life.
Alan D Dangour, Astrid E Fletcher, Balk, Carmel, Chou, Clarke, Cox, Dangour, de Jager, Delis, Diana Elbourne, Elizabeth Allen, Eussen, Fine, Fine, Folstein, Ford, Goldberg, Goodglass, Hin, Hunt, Institute of Medicine, Jernerén, Ken Whyte, Kerry Mills, Kimura, Leishear, Leishear, Lindenbaum, Louise Letley, Mann, Marcus Richards, Mills, Mills, O'Leary, Podsiadlo, Ricardo Uauy, Robert Clarke, Smith, Stabler, Sucharita, Sucharita, Tombaugh, Tombaugh, Turgut, Vellas, Watanabe, Yetley   +47 more
core   +1 more source

MODERN DIAGNOSTIC AND TREATMENT OF VITAMIN В12 DEFICIENCY

Klinicist, 2017
An article reflects modern concepts of the etiology of vitamin B12 deficiency including medication-induced conditions. Particular attention is paid to diagnostic algorithm in case of overt and latent forms of deficit.
A. L. Krasnovskiy, S. P. Grigor’iev, R. M. Alyokhina, I. S. Ezhova, I. V. Zolkina, E. O. Loshkareva   +5 more
doaj   +1 more source

Diagnostic reliability of serum active B12 (holo-transcobalamin) in true evaluation of vitamin B12 deficiency: Relevance in current perspective

BMC Research Notes, 2022
Objective Measurement of total vitamin B12 (vit B12) concentration raised concerns over early detection of vit B12 deficiency due to its clinical unreliability.
Rinini Dastidar, Kunal Sikder
doaj   +1 more source

Vitamin B12 Status in Recreational Users of Nitrous Oxide: A Systematic Review Focusing on the Prevalence of Laboratory Abnormalities

Antioxidants, 2023
The recreational use of nitrous oxide (N2O) as “laughing gas” is a growing problem. The chronic toxicity of N2O is mainly due to its ability to oxidize vitamin B12, making it dysfunctional as a cofactor in metabolic pathways. This mechanism plays a major
Tanguy Ménétrier, Damien Denimal
doaj   +1 more source

Algorithm for the early diagnosis of vitamin B12 deficiency in elderly people

Nutrición Hospitalaria, 2013
Background: The elderly population is particularly at risk for developing vitamin B12-deficiency. Serum cobalamin does not necessarily reflect a normal B12 status. The determination of methylmalonic acid is not available in all laboratories.
Gonzalo Palacios, Ricardo Sola, Laura Barrios, Klaus Pietrzik, Manuel J. Castillo, Marcela González-Gross   +5 more
doaj   +1 more source

Pre-conceptional Maternal Vitamin B12 Supplementation Improves Offspring Neurodevelopment at 2 Years of Age: PRIYA Trial

Frontiers in Pediatrics, 2021
Background: The first thousand days window does not include the pre-conceptional period. Maternal pre-conceptional health has a profound influence on early embryonic development (implantation, gastrulation, placentation etc).
Naomi D'souza, Rishikesh V. Behere, Bindu Patni, Madhavi Deshpande, Dattatray Bhat, Aboli Bhalerao, Swapnali Sonawane, Rohan Shah, Rasika Ladkat, Pallavi Yajnik, Souvik K. Bandyopadhyay, Kalyanaraman Kumaran, Caroline Fall, Chittaranjan S. Yajnik   +13 more
doaj   +1 more source

Holotranscobalamin remains unchanged during pregnancy. Longitudinal changes of cobalamins and their binding proteins during pregnancy and postpartum

Haematologica, 2007
We confirm a decrease in cobalamins during pregnancy, and report that the active part of cobalamins (holotranscobalamin, holoTC) remains unchanged. The decrease in cobalamins is explained by a decreased holohaptocorrin (holoHC), suggesting that holoTC ...
Anne L. Morkbak*, Anne-Mette Hvas, Nils Milman, Ebba Nexo   +3 more
doaj   +1 more source

Coexistence of pernicious anemia and prostate cancer - 'an experiment of nature' involving vitamin B₁₂ modulation of prostate cancer growth and metabolism: a case report

Journal of Medical Case Reports, 2009
Introduction This report presents the clinical and laboratory course of a patient with prostate cancer and severe vitamin B12 deficiency undergoing watchful waiting for prostate cancer.
Rainville Christa, Kutik Seth, Tisman Glenn   +2 more
doaj   +1 more source

Elevated Homocysteine after Elevated Propionylcarnitine or Low Methionine in Newborn Screening Is Highly Predictive for Low Vitamin B12 and Holo-Transcobalamin Levels in Newborns

Diagnostics, 2020
Early diagnostics and treatment of vitamin B12 deficiency (B12D) in infants, mainly maternally conditioned, is crucial in preventing possible developmental delay and neurological deficits.
Tomaž Rozmarič, Goran Mitulović, Vassiliki Konstantopoulou, Bernadette Goeschl, Martina Huemer, Barbara Plecko, Johannes Spenger, Saskia B. Wortmann, Sabine Scholl-Bürgi, Daniela Karall, Susanne Greber-Platzer, Maximilian Zeyda   +11 more
doaj   +1 more source

Cross-sectional association between vitamin B12 status and probable postpartum depression in Indian women

BMC Pregnancy and Childbirth, 2021
Background Vitamin B12 is an essential micronutrient for neurological function, as it leads to the regeneration of methionine from homocysteine, which is precursor of biologically active molecule S-Adenosyl Methionine (SAM).
Pooja Dhiman, Raji Ramachandran Pillai, Anand Babu Wilson, Nancy Premkumar, Balaji Bharadwaj, Veena P. Ranjan, Soundravally Rajendiran   +6 more
doaj   +1 more source