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Homeobox Gene Duplication and Divergence in Arachnids [PDF]

open access: yesMolecular Biology and Evolution, 2018
Homeobox genes are key toolkit genes that regulate the development of metazoans and changes in their regulation and copy number are thought to have contributed to the evolution of phenotypic diversity.
Nikola-Michael Prpic   +2 more
exaly   +10 more sources
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Homeoboxes in cnidarians

Journal of Experimental Zoology, 1991
AbstractHomeoboxes have previously been documented from various phyla of triploblastic, coelomate and pseudocoelomate, animals. We report here the first homeoboxes from cnidarians, a phylum of diploblastic organisms thought to occupy a near‐basal position in metazoan phylogeny.
B, Schierwater   +4 more
openaire   +2 more sources

Homeoboxes in flatworms

Gene, 1992
A search for homeobox-containing genes was done in the genome of a primitive metazoan, the parasitic tapeworm Echinococcus granulosus. Five different homeoboxes were isolated, none of them belonging to the classical Antennapedia-type. Three of the homeodomains are similar to those from the Drosophila melanogaster NK-type genes.
G, Oliver   +6 more
openaire   +2 more sources

Exploring the homeobox

Gene, 1993
In Drosophila, homeotic mutations lead to the transformation of structures of one body segment into the corresponding structures of another segment. These mutations identify master regulator genes which specify segmental identity along the antero-posterior body axis.
openaire   +3 more sources

The homeobox in perspective

Trends in Biochemical Sciences, 1992
The discovery of the homeobox marks the beginning of a new era in developmental biology in which a class of master control genes, which determine the body plan, have been identified. Their mechanism of action can now be studied at the molecular level and their occurrence seems to be much more universal than originally anticipated.
openaire   +3 more sources

Vertebrate homeobox genes

Genetica, 1994
In the former part of the review the principal available data about Hox genes, their molecular organisation and their expression in vertebrate embryos, with particular emphasis for mammals, are briefly summarized. In the latter part we analysed the expression of four mouse homeobox genes related to two Drosophila genes expressed in the developing head ...
Boncinelli E., Mallamaci A., Lavorgna G.
openaire   +3 more sources

Homeobox Genes and Cancer

Experimental Cell Research, 1999
Homeobox-containing genes are a family of regulatory genes encoding transcription factors that primarily play a crucial role during development. Several indications suggest their involvement in the control of cell growth and, when dysregulated, in oncogenesis.
CILLO, CLEMENTE   +3 more
openaire   +3 more sources

HOMEOTIC GENES AND THE HOMEOBOX

Annual Review of Genetics, 1986
INTRODUCTION ...... 147 PHENOTYPIC EFFECTS OF HOMEOTIC MUTATIONS . .. ....... 149 GENETIC AND MOLECULAR ORGANIZATION ..... 154 The Antennapedia Complex . . 154 The Bithorax Complex . .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 157 THE HOMEOBOX . . .. ...... .
W J, Gehring, Y, Hiromi
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Homeobox genes and the zootype

Nature, 1993
This Article does not have an ...
Miller, David, Miles, Annabel
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Homeoboxes in plant development

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, 1998
The homeobox is a 180 bp consensus DNA sequence present in a number of genes involved in developmental processes. This review focuses on the structure and function of plant homeobox genes and of the proteins they encode. Plant homeobox genes have been identified in studies using mutants, degenerate oligonucleotides deduced from conserved sequences ...
R L, Chan   +3 more
openaire   +2 more sources

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