Results 131 to 140 of about 119,108 (236)

Inconsistent Transcriptomic Responses to Hexabromocyclododecane in Japanese Quail: A Comparative Analysis of Results From Four Different Study Designs

Environmental Toxicology and Chemistry, EarlyView.
Abstract Efforts to use transcriptomics for toxicity testing have classically relied on the assumption that chemicals consistently produce characteristic transcriptomic signatures that are reflective of their mechanism of action. However, the degree to which transcriptomic responses are conserved across different test methodologies has seldom been ...
Paul Béziers, Elena Legrand, Emily Boulanger, Niladri Basu, Jessica D. Ewald, Paula Henry, Markus Hecker, Jianguo Xia, Natalie Karouna‐Renier, Doug Crump, Jessica Head   +10 more
wiley   +1 more source

Genome-Wide Identification and Analysis of the WUSCHEL-Related Homeobox (WOX) Gene Family in Passion Fruit (Passiflora edulis)

Agronomy
The WUSCHEL-related homeobox (WOX) transcription factors (TF) regulate critical developmental processes in plants, including organ formation and stem cell maintenance.
Jingai Gao, Dan Zhang, Lixin Xu, Ting Wu, Omotola Adebayo Olunuga, Mohammad Gul Arabzai, Xiaomei Wang, Ping Zheng, Yan Cheng, Boping Tang, Hanyang Cai, Yuan Qin, Lulu Wang   +12 more
doaj   +1 more source

Genetic Regulation of Vertebrate Forebrain Development by Homeobox Genes. [PDF]

Front Neurosci, 2022
Leung RF, George AM, Roussel EM, Faux MC, Wigle JT, Eisenstat DD.   +5 more
europepmc   +1 more source

Low HOX gene expression in PML-RARα-positive leukemia results from suppressed histone demethylation

Epigenetics, 2018
Homeobox (HOX) genes are frequently dysregulated in leukemia. Previous studies have shown that aberrant HOX gene expression accompanies leukemogenesis and affects disease progression and leukemia patient survival.
Katerina Rejlova, Alena Musilova, Karolina Skvarova Kramarzova, Marketa Zaliova, Karel Fiser, Meritxell Alberich-Jorda, Jan Trka, Julia Starkova   +7 more
doaj   +1 more source

Violation of cell lineage restriction compartments in the chick hindbrain [PDF]

, 1994
Previous cell lineage studies indicate that the repeated neuromeres of the chick hindbrain, the rhombomeres, are cell lineage restriction compartments. We have extended these results and tested if the restrictions are absolute. Two different cell marking
Birgbauer, Eric, Fraser, Scott E.
core  

Somatic cell reprogramming for Parkinson's disease treatment

Ibrain, Volume 11, Issue 1, Page 59-73, Spring 2025.
The fundamental purpose of cell reprogramming to treat Parkinson's disease is to generate dopaminergic neurons (DAN) and do transplantation. There are two ways to accomplish this. One method is to induce cells into induced DA neurons (iDAN) directly or to induce cells into induced pluripotent stem cells and ultimately into iDAN in vitro. Another option
Xiaozhuo Li, Kevin Fang, Fengping Wang
wiley   +1 more source

Vascular Calcification: Mechanisms, Models, and Therapies

iNew Medicine, EarlyView.
ABSTRACT Vascular calcification represents an active multifactorial process that mirrors several key features of skeletal bone mineralization. Clinically, it is characterized by diminished arterial compliance and increased arterial wall stiffness, both of which serve as independent predictors of significant adverse cardiovascular events.
Wenya Zhu, Shu Yang, Ziyi Chen, Xiaoxiao Yang, Zhen Liang, Yuanli Chen   +5 more
wiley   +1 more source

PRD-Class Homeobox Genes in Bovine Early Embryos: Function, Evolution, and Overlapping Roles. [PDF]

Mol Biol Evol, 2022
Lewin TD, Fouladi-Nashta AA, Holland PWH.   +2 more
europepmc   +1 more source

Zinc Finger E‐Box Binding Homeobox 1 Mediates Alcohol‐Induced Liver Disease

iNew Medicine, EarlyView.
Alcohol intake leads to the upregulation of ZEB1, which activates the YAP‐IL‐1β/MCP‐1 pathway, resulting in the activation of liver inflammation and the induction of hepatocyte apoptosis. ABSTRACT Hepatitis resulting from alcoholic liver disease (ALD) is an important risk factor for liver cancer. It is essential to understand the role of ALD to prevent
Boyu Zhang, Chunyang Zhang, Xiao Cui, Tao Xu, Xiangpeng Hu, Jiong Gu   +5 more
wiley   +1 more source

Homeobox Genes in Cancers: From Carcinogenesis to Recent Therapeutic Intervention. [PDF]

Front Oncol, 2021
Feng Y, Zhang T, Wang Y, Xie M, Ji X, Luo X, Huang W, Xia L.   +7 more
europepmc   +1 more source