The FEBS Journal, EarlyView.Chd4/NuRD and ThPOK cooperate to maintain transcriptional repression and nuclear organization in adult cardiomyocytes. Chd4 loss reduces miR‐150‐5p, relieving repression of Sprr1a, while ThPOK loss further enhances Sprr1a activation, possibly through altered chromatin–lamina interactions.
Fadoua El Abdellaoui‐Soussi +12 more
wiley +1 more source
Unlocking the HOX: Homeobox Genes as Regulators of Hematopoietic Development. [PDF]
Int J Mol SciMoyer DA, Henning AM, Medina KL.
europepmc +1 more source
Evaluating the Expression of Candidate Homeobox Genes and Their Role in Local-Site Inflammation in Mucosal Tissue Obtained from Children with Non-Syndromic Cleft Lip and Palate. [PDF]
J Pers Med, 2021 Jain N, Pilmane M.
europepmc +1 more source
From hepatic to hematopoietic: LRH‐1's expanding cellular repertoire to the immune system
The FEBS Journal, EarlyView.The nuclear receptor LRH‐1 is a well‐characterized regulator of endodermal tissue. Yet, increasing evidence indicates that LRH‐1, although expressed at low levels, is also a critical regulator of the hematopoietic system. LRH‐1 regulates the immune system by contributing to immune cell‐specific functions.
Lukas Meisinger +3 more
wiley +1 more source
Distinctive gene expression in the reduced first thoracic legs of a nymphalid butterfly
Insect Molecular Biology, EarlyView.Transcriptome analysis reveals that the small non‐walking front legs of a butterfly have distinct gene expression to the four walking legs. Reduced front legs express a gene with putative mechanosensory roles, a blue‐sensitive opsin and two homeobox genes.
Asia E. Hoile +2 more
wiley +1 more source
Harnessing Endogenous Homeobox Genes for Synthetic Apomixis in Hybrid Rice. [PDF]
Plant Biotechnol JWei X +7 more
europepmc +1 more source
Transformation of Nicotiana paniculata L., a recalcitrant species, using a T-DNA construct carrying two WUSCHEL-related homeobox genes. [PDF]
Plant Biotechnol (Tokyo), 2023 Kyo M, Hagiya M, Tada M, Matsura A.
europepmc +1 more source
Journal of Diabetes Investigation, EarlyView.In this study, we uncovered that Hypo‐Exo transferring H19 promoted diabetic wound healing by repressing NETs formation via the miR‐130a/b‐3p/HOXA5 pathway to inactivate the TLR4/NF‐κB/NLRP3 inflammatory signaling. ABSTRACT Background Hypoxia‐stimulated adipose‐derived mesenchymal stem cells (ADSCs)‐derived exosomes (Hypo‐Exo) have a positive impact on
Li Qian +3 more
wiley +1 more source
The Chronological Trigger: The Orchestra Between Homeobox Genes and the Circadian Clock During Development. [PDF]
Biol CellPoloni JF, Feltes BC.
europepmc +1 more source
Tree growth response and adaptation to climate change and climate extremes: From canopy to stem
Journal of Integrative Plant Biology, EarlyView.This review synthesizes the responses and adaptations of tree growth, including canopy phenology, intra‐annual wood formation dynamics, and annual stem growth, to climate change and climate extremes. It highlights key knowledge gaps for future research to support sustainable forest management and enhance forest carbon storage under ongoing climate ...
Feiyu Yang +8 more
wiley +1 more source