Results 1 to 10 of about 82,771 (160)

Widespread employment of conserved C. elegans homeobox genes in neuronal identity specification

open access: yesPLoS Genetics, 2022
Homeobox genes are prominent regulators of neuronal identity, but the extent to which their function has been probed in animal nervous systems remains limited.
Jayson Smith   +2 more
exaly   +4 more sources

The Aspergillus flavus Homeobox Gene, hbx1, Is Required for Development and Aflatoxin Production

open access: yesToxins, 2017
Homeobox proteins, a class of well conserved transcription factors, regulate the expression of targeted genes, especially those involved in development.
Sourav Banerjee   +2 more
exaly   +3 more sources

Homeobox Genes and Hepatocellular Carcinoma [PDF]

open access: yesCancers, 2019
Hepatocellular carcinoma (HCC) is the sixth most common type of cancer, and is the third leading cause of cancer-related deaths each year. It involves a multi-step progression and is strongly associated with chronic inflammation induced by the intake of environmental toxins and/or viral infections (i.e., hepatitis B and C viruses).
Li-Ting Wang   +2 more
exaly   +3 more sources

Genome-Wide Analysis of Homeobox Gene Family in Legumes: Identification, Gene Duplication and Expression Profiling [PDF]

open access: yesPLoS ONE, 2015
Homeobox genes encode transcription factors that are known to play a major role in different aspects of plant growth and development. In the present study, we identified homeobox genes belonging to 14 different classes in five legume species, including ...
Rohini Garg   +2 more
exaly   +2 more sources

The Homeobox Genes: Classification, Regulation, Biological Functions, and Diseases [PDF]

open access: yesMedComm
Homeobox genes constitute a large family of transcription factors that act as master regulators involved in multiple fundamental processes such as development and cell differentiation.
Maedeh Dadzadi   +5 more
doaj   +2 more sources

Sustained expression of unc-4 homeobox gene and unc-37/Groucho in postmitotic neurons specifies the spatial organization of the cholinergic synapses in C. elegans

open access: yeseLife, 2021
Neuronal cell fate determinants establish the identities of neurons by controlling gene expression to regulate neuronal morphology and synaptic connectivity.
Mizuki Kurashina   +5 more
doaj   +1 more source

Identification of Novel Genetic Variants Related to Trabecular Bone Score in Community-Dwelling Older Adults [PDF]

open access: yesEndocrinology and Metabolism, 2020
Background As the genetic variants of trabecular bone microarchitecture are not well-understood, we performed a genome-wide association study to identify genetic determinants of bone microarchitecture analyzed by trabecular bone score (TBS).
Sung Hye Kong   +8 more
doaj   +1 more source

Genetic Regulation of Vertebrate Forebrain Development by Homeobox Genes

open access: yesFrontiers in Neuroscience, 2022
Forebrain development in vertebrates is regulated by transcription factors encoded by homeobox, bHLH and forkhead gene families throughout the progressive and overlapping stages of neural induction and patterning, regional specification and generation of
Ryan F. Leung   +12 more
doaj   +1 more source

HOXA Amplification Defines a Genetically Distinct Subset of Angiosarcomas

open access: yesBiomolecules, 2022
Angiosarcoma is a rare, devastating malignancy with few curative options for disseminated disease. We analyzed a recently published genomic data set of 48 angiosarcomas and noticed recurrent amplifications of HOXA-cluster genes in 33% of patients.
Hongbo M. Xie, Kathrin M. Bernt
doaj   +1 more source

OVEREXPRESSION OF WUSCHEL IMPROVES THE INDUCTION OF EMBRYOGENIC CALLUS IN SCALPS OF MUSA ACUMINATA L. AAA, CV. “GRAND NAIN”

open access: yesTropical and Subtropical Agroecosystems, 2023
Background: During the last few years the home box transcription factor WUSCHEL (WUS) has been shown to cause dedifferentiation when expressed on somatic cells followed by a production of new stem cells that can lead to somatic embryogenesis or ...
Ana Ly Arroyo Herrera   +7 more
doaj   +1 more source

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