Results 41 to 50 of about 99,018 (274)
‘Organ’ising Floral Organ Development
PlantsFlowers are plant structures characteristic of the phylum Angiosperms composed of organs thought to have emerged from homologous structures to leaves in order to specialize in a distinctive function: reproduction.
Kestrel A. Maio, Laila Moubayidin
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Advanced Healthcare Materials, EarlyView.A heart‐on‐a‐chip model of dilated cardiomyopathy is developed from patient‐derived induced pluripotent stem cells. The model recapitulates key disease phenotypes and enables functional assessment through integrated bead‐based tracking and pillar deflection measurements.
Ali Mousavi +10 more
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Cells, 2018 Skeletogenesis, remodeling, and maintenance in adult tissues are regulated by sequential activation of genes coding for specific transcription factors.
Arkaitz Mucientes +6 more
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Advanced Healthcare Materials, EarlyView.We developed a patient‐derived, functional microfluidic model of the diffuse midline glioma (DMG) blood–brain–tumor barrier (BBTB) comprised of endothelial cells, astrocytes, pericytes, and tumor cells. The system forms perfusable microvasculature, reveals the BBTB retains vascular integrity, identifies DMG‐specific transcriptomic changes distinct from
Kimberly R. Bennett +7 more
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Diagnostics, 2023 Homeobox genes serve as master regulatory transcription factors that regulate gene expression during embryogenesis. A homeobox gene may have either tumor-promoting or tumor-suppressive properties depending on the specific organ or cell lineage where it ...
Fee-Wai Chin +2 more
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An update on the vertebrate homeobox [PDF]
Trends in Genetics, 1989 Given the complexity of development and the multitude of differentiated cell types in higher eukaryotic organisms, one might expect that a large variety of proteins would be required to regulate specific developmental processes. However, if the differentiated state of a particular cell is specified not by a single protein but by a combination of ...
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Advanced Materials, EarlyView.Spatiotemporal control over cell behavior within bioprinted constructs remains a key challenge in biofabrication. Volumetric bioprinting using multi‐wavelength light sources permits to activate light‐sensitive intracellular proteins as well as optogenetic gene and protein expression circuits in bioprinted cells, in addition to enabling fast printing of
Davide Ribezzi +14 more
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Notulae Botanicae Horti Agrobotanici Cluj-NapocaHomeobox (HB) transcription factors are key regulators for plant growth, development, and responses to environmental stress adaptation. However, the HB-other subfamily remains poorly characterized in most plant species.
Salha Mesfer Alshamrani +1 more
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eLife, 2015 The role of mechanical signals in cell identity determination remains poorly explored in tissues. Furthermore, because mechanical stress is widespread, mechanical signals are difficult to uncouple from biochemical-based transduction pathways.
Benoît Landrein +12 more
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Charting Endocrine Progenitors Across Species and Organs
Advanced Science, EarlyView.Endocrine progenitors give rise to the hormone‐producing cells of the pancreas and intestine. Using single‐cell multiomics and proteomics, this study compares these progenitors across species, systems, and organs, mapping the conserved and species‐specific gene regulatory networks that guide their formation.
Changying Jing +21 more
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