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The hair follicle is a complex mini-organ in the skin that undergoes organ induction, morphogenesis, and regeneration. However, the accurate molecular mechanism of skin and hair diversity regulation is still elusive. The sheep is an animal model that can
Tianyou Bai +7 more
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The Aspergillus flavus Homeobox Gene, hbx1, Is Required for Development and Aflatoxin Production
Homeobox proteins, a class of well conserved transcription factors, regulate the expression of targeted genes, especially those involved in development.
Jeffrey W. Cary +11 more
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Androgen-induced rhox homeobox genes modulate the expression of AR-regulated genes [PDF]
Rhox5, the founding member of the reproductive homeobox on the X chromosome (Rhox) gene cluster, encodes a homeodomain-containing transcription factor that is selectively expressed in Sertoli cells, where it promotes the survival of male germ cells ...
Hu, Z.Y. +7 more
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Homeobox transcription factors play critical roles in plant development and abiotic stress responses. In the present study, we raised rice transgenics over-expressing stress-responsive OsHOX24 gene (rice homeodomain-leucine zipper I sub-family member ...
Mukesh Jain +3 more
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The phytopathogenic fungus Colletotrichum scovillei, belonging to the Colletotrichum acutatum species complex, causes severe anthracnose disease on several fruits, including chili pepper (Capsicum annuum). However, the molecular mechanisms underlying the
Teng Fu +4 more
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Lack of the murine homeobox gene Hesx1 leads to a posterior transformation of the anterior forebrain [PDF]
The homeobox gene Hesx1 is an essential repressor that is required within the anterior neural plate for normal forebrain development in mouse and humans. Combining genetic cell labelling and marker analyses, we demonstrate that the absence of Hesx1 leads
Andoniadou, CL +27 more
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The Homeobox Transcription Factor RHOX10 Drives Mouse Spermatogonial Stem Cell Establishment
The developmental origins of most adult stem cells are poorly understood. Here, we report the identification of a transcription factor—RHOX10—critical for the initial establishment of spermatogonial stem cells (SSCs).
Hye-Won Song +16 more
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HMBOX1, a member of the homeobox family: current research progress
Homeobox containing 1 (HMBOX1) is a transcription factor that was identified in 2006 from a cDNA library of the human pancreas. It belongs to the HNF gene class of the homeobox family.
Yu Jiang, Hengli Zhao, Hongli Mu
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Despite much effort to improve treatments, patients with malignant glioma still present a very poor prognosis that has not changed significantly in the last decades.
Céline S. Gonçalves +8 more
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Hyperconserved Elements in Human 5′UTRs Shape Essential Post-transcriptional Regulatory Networks
Post-transcriptional regulation (PTR) of gene expression is a powerful determinant of cellular phenotypes. The 5′ and 3′ untranslated regions of the mRNA (UTRs) mediate this role through sequence and secondary structure elements bound by RNA-binding ...
Paola Zuccotti +4 more
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