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The Role of NKL Homeobox Genes in T-Cell Malignancies
Biomedicines, 2021 Homeobox genes encode transcription factors controlling basic developmental processes. The homeodomain is encoded by the homeobox and mediates sequence-specific DNA binding and interaction with cofactors, thus operating as a basic regulatory platform ...
Stefan Nagel
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The Homeobox Only Protein Homeobox (HOPX) and Colorectal Cancer [PDF]
International Journal of Molecular Sciences, 2013 The HOP (homeobox only protein) homeobox (HOPX) is most closely related to the homeobox protein that contains a homeobox-like domain but lacks certain conserved residues required for DNA binding. Here, we review the current understanding of HOPX in the progression of colorectal cancer (CRC).
Yamashita, Keishi +2 more
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Homeobox genes in normal and abnormal vasculogenesis [PDF]
, 2008 Homeobox containing genes are a family of transcription factors regulating normal development and controlling primary cellular processes (cell identity, cell division and differentiation) recently enriched by the discovery of their interaction with ...
Cantile M +3 more
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Agriculture, 2021 The hair follicle is a complex mini-organ in the skin that undergoes organ induction, morphogenesis, and regeneration. However, the accurate molecular mechanism of skin and hair diversity regulation is still elusive. The sheep is an animal model that can
Tianyou Bai +7 more
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HOXD8 exerts a tumor-suppressing role in colorectal cancer as an apoptotic inducer [PDF]
, 2017 Homeobox (HOX) genes are conserved transcription factors which determine the anterior-posterior body axis patterning. HOXD8 is a member of HOX genes deregulated in several tumors such as lung carcinoma, neuroblastoma, glioma and colorectal cancer (CRC ...
Mansour, Mohammed A., Senga, Takeshi
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Homeobox Is Pivotal for OsWUS Controlling Tiller Development and Female Fertility in Rice
G3: Genes, Genomes, Genetics, 2016 OsWUS has recently been shown to be a transcription factor gene critical for tiller development and fertility in rice. The OsWUS protein consists of three conserved structural domains, but their biological functions are still unclear. We discovered a new
Fredrick Mwamburi Mjomba +6 more
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Unleashing floret fertility in wheat through the mutation of a homeobox gene
Proceedings of the National Academy of Sciences of the United States of America, 2019 Significance Grain number is a key determinant of cereal grain yield, but its underlying genetic basis in wheat remains undefined. This study demonstrates a direct association between increased floret fertility, higher grain number per spike, and higher ...
Shun Sakuma +16 more
semanticscholar +1 more source
Frontiers in Microbiology, 2022 The phytopathogenic fungus Colletotrichum scovillei, belonging to the Colletotrichum acutatum species complex, causes severe anthracnose disease on several fruits, including chili pepper (Capsicum annuum). However, the molecular mechanisms underlying the
Teng Fu +4 more
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NaNog: A pluripotency homeobox (master) molecule. [PDF]
, 2015 One of the most intriguing aspects of cell biology is the state of pluripotency, where the cell is capable of self-renewal for as many times as deemed necessary , then at a specified time can differentiate into any type of cell. This fundamental process
Aguib, YE +4 more
core +1 more source
Frontiers in Plant Science, 2017 Homeobox transcription factors play critical roles in plant development and abiotic stress responses. In the present study, we raised rice transgenics over-expressing stress-responsive OsHOX24 gene (rice homeodomain-leucine zipper I sub-family member ...
Mukesh Jain +3 more
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