Results 11 to 20 of about 82,771 (160)

The Homeobox Only Protein Homeobox (HOPX) and Colorectal Cancer [PDF]

open access: yesInternational Journal of Molecular Sciences, 2013
The HOP (homeobox only protein) homeobox (HOPX) is most closely related to the homeobox protein that contains a homeobox-like domain but lacks certain conserved residues required for DNA binding. Here, we review the current understanding of HOPX in the progression of colorectal cancer (CRC).
Yamashita, Keishi   +2 more
openaire   +2 more sources

A sister of NANOG regulates genes expressed in pre-implantation human development [PDF]

open access: yesOpen Biology, 2017
The NANOG homeobox gene plays a pivotal role in self-renewal and maintenance of pluripotency in human, mouse and other vertebrate embryonic stem cells, and in pluripotent cells of the blastocyst inner cell mass.
Thomas L. Dunwell, Peter W. H. Holland
doaj   +1 more source

The Role of NKL Homeobox Genes in T-Cell Malignancies

open access: yesBiomedicines, 2021
Homeobox genes encode transcription factors controlling basic developmental processes. The homeodomain is encoded by the homeobox and mediates sequence-specific DNA binding and interaction with cofactors, thus operating as a basic regulatory platform ...
Stefan Nagel
doaj   +1 more source

The homeobox in vertebrate development [PDF]

open access: yesCurrent Opinion in Cell Biology, 1989
http://dx.doi.org/
Goulding, M., Gruss, P.
openaire   +3 more sources

Homeobox Is Pivotal for OsWUS Controlling Tiller Development and Female Fertility in Rice

open access: yesG3: Genes, Genomes, Genetics, 2016
OsWUS has recently been shown to be a transcription factor gene critical for tiller development and fertility in rice. The OsWUS protein consists of three conserved structural domains, but their biological functions are still unclear. We discovered a new
Fredrick Mwamburi Mjomba   +6 more
doaj   +1 more source

Transcriptome Analysis Reveals Candidate Genes Regulating the Skin and Hair Diversity of Xinji Fine-Wool Sheep and Tan Sheep

open access: yesAgriculture, 2021
The hair follicle is a complex mini-organ in the skin that undergoes organ induction, morphogenesis, and regeneration. However, the accurate molecular mechanism of skin and hair diversity regulation is still elusive. The sheep is an animal model that can
Tianyou Bai   +7 more
doaj   +1 more source

Over-Expression of OsHOX24 Confers Enhanced Susceptibility to Abiotic Stresses in Transgenic Rice via Modulating Stress-Responsive Gene Expression

open access: yesFrontiers in Plant Science, 2017
Homeobox transcription factors play critical roles in plant development and abiotic stress responses. In the present study, we raised rice transgenics over-expressing stress-responsive OsHOX24 gene (rice homeodomain-leucine zipper I sub-family member ...
Mukesh Jain   +3 more
doaj   +1 more source

Mitogen-Activated Protein Kinase CsPMK1 Is Essential for Pepper Fruit Anthracnose by Colletotrichum scovillei

open access: yesFrontiers in Microbiology, 2022
The phytopathogenic fungus Colletotrichum scovillei, belonging to the Colletotrichum acutatum species complex, causes severe anthracnose disease on several fruits, including chili pepper (Capsicum annuum). However, the molecular mechanisms underlying the
Teng Fu   +4 more
doaj   +1 more source

The Homeobox Transcription Factor RHOX10 Drives Mouse Spermatogonial Stem Cell Establishment

open access: yesCell Reports, 2016
The developmental origins of most adult stem cells are poorly understood. Here, we report the identification of a transcription factor—RHOX10—critical for the initial establishment of spermatogonial stem cells (SSCs).
Hye-Won Song   +16 more
doaj   +1 more source

A novel molecular link between HOXA9 and WNT6 in glioblastoma identifies a subgroup of patients with particular poor prognosis

open access: yesMolecular Oncology, 2020
Despite much effort to improve treatments, patients with malignant glioma still present a very poor prognosis that has not changed significantly in the last decades.
Céline S. Gonçalves   +8 more
doaj   +1 more source

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