Results 11 to 20 of about 159,528 (240)
The role of homeobox genes in retinal development and disease
Developmental Biology, 2014 Homeobox genes are an evolutionarily conserved class of transcription factors that are critical for development of many organ systems, including the brain and eye.
Vanessa I Pinto +2 more
exaly +2 more sources
WIREs Developmental Biology, 2012 AbstractMany homeobox genes encode transcription factors with regulatory roles in animal and plant development. Homeobox genes are found in almost all eukaryotes, and have diversified into 11 gene classes and over 100 gene families in animal evolution, and 10 to 14 gene classes in plants.
P. Holland
openaire +3 more sources
A comparative analysis of transcription factor expression during metazoan embryonic development [PDF]
, 2013 During embryonic development, a complex organism is formed from a single starting cell. These processes of growth and differentiation are driven by large transcriptional changes, which are following the expression and activity of transcription factors ...
Adryan, Boris, Schep, Alicia
core +18 more sources
eLife, 2021 Neuronal cell fate determinants establish the identities of neurons by controlling gene expression to regulate neuronal morphology and synaptic connectivity.
Mizuki Kurashina +5 more
doaj +1 more source
Identification of Novel Genetic Variants Related to Trabecular Bone Score in Community-Dwelling Older Adults [PDF]
Endocrinology and Metabolism, 2020 Background As the genetic variants of trabecular bone microarchitecture are not well-understood, we performed a genome-wide association study to identify genetic determinants of bone microarchitecture analyzed by trabecular bone score (TBS).
Sung Hye Kong +8 more
doaj +1 more source
Genetic Regulation of Vertebrate Forebrain Development by Homeobox Genes
Frontiers in Neuroscience, 2022 Forebrain development in vertebrates is regulated by transcription factors encoded by homeobox, bHLH and forkhead gene families throughout the progressive and overlapping stages of neural induction and patterning, regional specification and generation of
Ryan F. Leung +12 more
doaj +1 more source
HOXA Amplification Defines a Genetically Distinct Subset of Angiosarcomas
Biomolecules, 2022 Angiosarcoma is a rare, devastating malignancy with few curative options for disseminated disease. We analyzed a recently published genomic data set of 48 angiosarcomas and noticed recurrent amplifications of HOXA-cluster genes in 33% of patients.
Hongbo M. Xie, Kathrin M. Bernt
doaj +1 more source
Tropical and Subtropical Agroecosystems, 2023 Background: During the last few years the home box transcription factor WUSCHEL (WUS) has been shown to cause dedifferentiation when expressed on somatic cells followed by a production of new stem cells that can lead to somatic embryogenesis or ...
Ana Ly Arroyo Herrera +7 more
doaj +1 more source
Unique homeobox codes delineate all C. elegans neuron classes
Nature, 2020 It is not known at present whether neuronal cell-type diversity—defined by cell-type-specific anatomical, biophysical, functional and molecular signatures—can be reduced to relatively simple molecular descriptors of neuronal identity1.
Molly B. Reilly +4 more
semanticscholar +1 more source
A sister of NANOG regulates genes expressed in pre-implantation human development [PDF]
Open Biology, 2017 The NANOG homeobox gene plays a pivotal role in self-renewal and maintenance of pluripotency in human, mouse and other vertebrate embryonic stem cells, and in pluripotent cells of the blastocyst inner cell mass.
Thomas L. Dunwell, Peter W. H. Holland
doaj +1 more source