Microduplication 10q24.31 in a Spanish girl with scoliosis and myopathy:the critical role of LBX [PDF]
Calleja-Perez, Beatriz +9 more
core +2 more sources
Harnessing Endogenous Homeobox Genes for Synthetic Apomixis in Hybrid Rice. [PDF]
Wei X +7 more
europepmc +1 more source
Transformation of Nicotiana paniculata L., a recalcitrant species, using a T-DNA construct carrying two WUSCHEL-related homeobox genes. [PDF]
Kyo M, Hagiya M, Tada M, Matsura A.
europepmc +1 more source
A guide to the types, structures, and multifaceted functions of matrix metalloproteinases in cancer
Matrix metalloproteinases (MMPs) orchestrate cancer progression and metastasis through proteolytic and non‐proteolytic actions. By remodeling the tumor microenvironment, enhancing growth factor availability, and modulating cell behavior, MMPs promote proliferation, migration or invasion, and epithelial‐to‐mesenchymal transition. Alongside extracellular
Zoi Piperigkou +4 more
wiley +1 more source
The Chronological Trigger: The Orchestra Between Homeobox Genes and the Circadian Clock During Development. [PDF]
Poloni JF, Feltes BC.
europepmc +1 more source
Regulation of PHOX2B gene expression by the long non‐coding natural antisense RNA PHOX2B‐AS1
PHOX2B is a transcription factor essential for autonomic nervous system development. We identify and characterize PHOX2B‐AS1, a human long non‐coding antisense transcript at the PHOX2B locus, along with its murine counterpart. Our findings reveal bidirectional transcription and reciprocal regulation: PHOX2B activates PHOX2B‐AS1, whereas PHOX2B‐AS1 ...
Simona Di Lascio +12 more
wiley +1 more source
Quantitative analysis of DNA‐GATA1 binding alterations linked to hematopoietic disorders
Native holdup allows the quantitative determination of affinities between full‐length transcription factors and DNA. Mutations in either the protein or the DNA can modulate binding strength, which can be precisely quantified using this approach. Applied to GATA1, it revealed mutations that alter DNA binding.
Boglarka Zambo +6 more
wiley +1 more source
Deficiency of UBE3D in mice leads to severe embryonic abnormalities and disrupts the mRNA of Homeobox genes via CPSF3. [PDF]
Mi Y, Yan L, Wu Y, Zheng Y.
europepmc +1 more source
Nomenclature for human homeobox genes
P J, McAlpine, T B, Shows
openaire +2 more sources
Chd4/NuRD and ThPOK cooperate to maintain transcriptional repression and nuclear organization in adult cardiomyocytes. Chd4 loss reduces miR‐150‐5p, relieving repression of Sprr1a, while ThPOK loss further enhances Sprr1a activation, possibly through altered chromatin–lamina interactions.
Fadoua El Abdellaoui‐Soussi +12 more
wiley +1 more source

