Results 21 to 30 of about 1,687,854 (353)
An optimized base editor with efficient C-to-T base editing in zebrafish
BMC Biology, 2020 Background Zebrafish is a model organism widely used for the understanding of gene function, including the fundamental basis of human disease, enabled by the presence in its genome of a high number of orthologs to human genes.
Yu Zhao +4 more
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Regulation of genes involved in carnitine homeostasis by PPARa across different species (rat, mouse, pig, cattle, chicken, and human) [PDF]
, 2012 Recent studies in rodents convincingly demonstrated that PPAR-alpha is a key regulator of genes involved in carnitine homeostasis, which serves as a reasonable explanation for the phenomenon that energy deprivation and fibrate treatment, both of which ...
Egeri, Leonie +4 more
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Nature Communications, 2020 The protein Insig-2 negatively regulates lipid biosynthesis and is short-lived in liver cells but stable in muscle cells. Here, the authors show that in muscle cells producing reactive oxygen species, there is increased oxidation compared to ...
Zhang-Sen Zhou +11 more
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Journal of Fungi, 2021 Carbon catabolite repression (CCR) is critical for the preferential utilization of glucose derived from environmental carbon sources and regulated by carbon catabolite repressor A (Cre1/CreA) in filamentous fungi.
Rehab Abdelmonem Mohamed +4 more
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Integrative concept of homeostasis: translating physiology into medicine [PDF]
, 2011 To truly understand living systems they must be viewed as a whole. In order to achieve this and to come to some law to which living systems obey, data obtained on cells, tissues and organs should be integrated.
Ivan Spasojevic, Ivan Spasojevic
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Intestinal stem cell proliferation and epithelial homeostasis in the adult Drosophila midgut [PDF]
, 2015 Adult tissue homeostasis requires a tight balance between the removal of old or damaged cells and the production of new ones. Such processes are usually driven by dedicated stem cells that reside within specific tissue locations or niches.
Carroll, Lynsey +2 more
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Frontiers in Microbiology, 2019 DNA methylation serves as a vital component of restriction-modification (R-M) systems in bacteria, where it plays a crucial role in defense against foreign DNA.
Shengjie Li +11 more
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Journal of Experimental & Clinical Cancer Research, 2018 Background Tetrandrine, a bisbenzylisoquinoline alkaloid that was isolated from the medicinal plant Stephania tetrandrine S. Moore, was recently identified as a novel chemotherapy drug. Tetrandrine exhibited a potential antitumor effect on multiple types
Man Yu +4 more
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Risk homeostasis in information security:challenges in confirming existence and verifying impact [PDF]
, 2017 The central premise behind risk homeostasis theory is that humans adapt their behaviors, based on external factors, to align with a personal risk tolerance level.
Renaud, Karen, Warkentin, Merrill
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mSphere, 2022 The yeast-to-filament transition is an important cellular response to environmental stimulations in dimorphic fungi. In addition to activators, there are repressors in the cells to prevent filament formation, which is important to keep the cells in the ...
Jia-Wen Chen +3 more
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