Results 51 to 60 of about 1,571 (154)

3-Methyl-2-((methylthio)methyl)but-2-enal

Molbank
During the Swern oxidation of 3-methylbut-3-en-1-ol, an unexpected C-C bond formation product, 3-methyl-2-(methylthio)but-2-enal, was obtained. Its structure was characterized using 1H-NMR, 13C-NMR, and HRMS.
Huaxuan Zhang, Xingang Xie
doaj   +1 more source

Non‐redox Lewis Acids Supported Pd‐Catalyzed C—C /C—H Activation and Accession to Produce Pharmaceutical Intermediates

ChemistryOpen, Volume 15, Issue 4, April 2026.
Palladium is a simple and versatile redox‐active metal that plays a crucial role in the oxidation reactions for organic synthesis and production of pharmaceutical intermediates. Notably, there has been significant progress with Lewis acids (LAs), which are non‐redox metal ions promoting Pd(II)‐catalyzed oxidation via C—H and C—C bond activation.
Ahmed M. Senan, Senem Akkoc, A. M. Abdulkarem, Sadeq K. Alhag   +3 more
wiley   +1 more source

Efficient, highly diastereoselective MS 4 Å-promoted one-pot, three-component synthesis of 2,6-disubstituted-4-tosyloxytetrahydropyrans via Prins cyclization

Beilstein Journal of Organic Chemistry, 2012
A simple, efficient and highly diastereoselective one-pot three-component synthesis of functionalized 2,6-disubstituted-4-tosyloxytetrahydropyrans was performed.
Naseem Ahmed, Naveen Kumar Konduru
doaj   +1 more source

Allylation of aldehydes with various allylation agents

Results in Chemistry
Allylation of aldehydes is one of the most important organic transformations that helps in the synthesis of compounds with special skeletons with unique medicinal properties.
Yavar Ahmadi
doaj   +1 more source

Complementary Synthesis of Anti- and Syn-Hydroxymethyl 1,3-Diols via Regioselective Ring Opening of TIPS-Protected 2,3-Epoxy Alcohols: Toward Polypropionate Fragments

Organics
Hydroxymethyl 1,3-diol motifs are common structural motifs in natural products, particularly in polypropionates with important therapeutic potential.
Raúl R. Rodríguez-Berríos, José A. Prieto   +1 more
doaj   +1 more source

Reductively Stable Platinum Catalyst Enabling Metallaphotoredox Reductive Allylation of Ketones, Aldehydes, and Imines

ChemistryEurope
This work demonstrates the catalytic reductive allylation of ketones, aldehydes, and imines using a synergistic platinum/photoredox catalyst system. Notably, this method is applicable even to acetophenone derivatives, affording homoallylic alcohols that ...
Junpei Shimosato, Kousei Nishimura, Bunta Fukuyo, Yohei Shimizu, Masaya Sawamura, Yusuke Masuda   +5 more
doaj   +1 more source

Overcoming the Usual Reactivity of β-Nitroenones: Synthesis of Polyfunctionalized Homoallylic Alcohols and Conjugated Nitrotriene Systems. [PDF]

J Org Chem, 2023
Yuan L, Kachalova L, Khan MEI, Ballini R, Petrini M, Palmieri A.   +5 more
europepmc   +1 more source

Catalytic Markovnikov hydrophosphorylation of unactivated olefins via a radical-polar crossover rearrangement

Nature Communications
The phosphorylation of alkenes offers a diverse handle for obtaining organophosphoryls, but its regioselectivity still faces challenges, especially the radical Markovnikov hydrophosphorylation of alkenes.
Yi-Fan Li, Hong-Chen Wang, Bing Han
doaj   +1 more source

Preparation of aromatic geraniol analogues via a Cu(I)-mediated Grignard coupling

Journal of the Brazilian Chemical Society, 2003
Difunctional allylic terpenes are important synthetic building blocks. Functionalization of protected geranyl derivatives by SeO2/t-BuO2H adsorbed on SiO2 provides a convenient route to such compounds.
Paz J. Luis, Rodrigues J. Augusto R.
doaj  

Base-Promoted C-C Bond Activation Enables Radical Allylation with Homoallylic Alcohols. [PDF]

J Am Chem Soc, 2020
Lübbesmeyer M, Mackay EG, Raycroft MAR, Elfert J, Pratt DA, Studer A.   +5 more
europepmc   +1 more source