Results 31 to 40 of about 108,077 (187)

Asymmetric synthesis of homoallylic alcohols and their applications [PDF]

, 2011
Herein it is presented a further development of the well-established catalytic asymmetric allylation of aldehydes leading to enantiopure homoallylic alcohols Stereogenic centre(s) served as the foundation for synthesis of a variety of other advanced ...
Barlog, Maciej L.
core   +6 more sources

Palladium-Catalyzed Enantiospecific Three-Component Reaction for the Synthesis of 1,2,4-Trisubstituted Homoallylic Alcohols

Organics
1,2,4-Trisubstituted chiral homoallylic alcohols are valuable intermediates in natural product synthesis and complex molecular architectures; however, their catalytic asymmetric synthesis remains challenging due to the need for precise control of ...
Ayumu Natsubori, Momoka Ikeda, Yushin Hosokawa, Mizuki Akagawa, Yoshikazu Horino   +4 more
doaj   +1 more source

Use of Cyclic Allylic Bromides in the Zinc–Mediated Aqueous Barbier–Grignard Reaction

Molecules, 2001
The zinc–mediated aqueous Barbier–Grignard reaction of cyclic allylic bromide substrates with various aldehydes and ketones to afford homoallylic alcohols was investigated. Aromatic aldehydes and ketones afforded adducts in good yields (66–
Suzanne M. Perala, Brian P. Conrad, Christine A. Hughey, John H. Shugart, Gary W. Breton   +4 more
doaj   +1 more source

Cobalt-catalyzed nucleophilic addition of the allylic C(sp3)–H bond of simple alkenes to ketones

Beilstein Journal of Organic Chemistry, 2018
We herein describe a cobalt/Xantphos-catalyzed regioselective addition of simple alkenes to acetophenone derivatives, affording branched homoallylic alcohols in high yields with perfect branch selectivities.
Tsuyoshi Mita, Masashi Uchiyama, Kenichi Michigami, Yoshihiro Sato   +3 more
doaj   +1 more source

Methyltrioxorhenium-Catalyzed Epoxidation of Homoallylic Alcohols with Hydrogen Peroxide

, 2016
Homoallylic alcohols were efficiently converted to the corresponding 3,4-epoxy alcohols in excellent yields by methyltrioxorhenium (MTO)-catalyzed epoxidation with aqueous hydrogen peroxide as the terminal oxidant and 3-methylpyrazole (10 mol %) as an ...
Shigekazu Yamazaki (2028916)
core   +1 more source

Three-component coupling of aryl iodides, allenes, and aldehydes catalyzed by a Co/Cr-hybrid catalyst

Beilstein Journal of Organic Chemistry, 2018
The cobalt/chromium-catalyzed three-component coupling of aryl iodides, allenes, and aldehydes has been developed to afford multi-substituted homoallylic alcohols in a diastereoselective manner.
Kimihiro Komeyama, Shunsuke Sakiyama, Kento Iwashita, Itaru Osaka, Ken Takaki   +4 more
doaj   +1 more source

Reaction of Thallium(III) Salts with Homoallylic Alcohols: Ring Contraction vs. Dimethoxylation

Molecules, 2005
The oxidation of 2-(3,4-dihydronaphthalen-1-yl)-ethanol (1) with a variety ofthallium(III) salts was investigated. An indan, formed by a ring contraction reaction, wasobtained in good to moderate yields under a variety of reaction conditions: i ...
Marcus V. Craveiro, Luiz F. Silvia
doaj   +1 more source

Toward the Synthesis of Pestalustaine A: Structural Revision and Formation of Original Strained Tricyclic Architectures

Angewandte Chemie, Volume 138, Issue 37, 7 September 2026.
Our synthetic endeavor toward the total synthesis of the reported unprecedented tricyclic skeleton of the sesquiterpene pestalustaine A allowed us to perform divergent cyclizations of a bicyclo[4.4.1]undec‐3‐ene into complex tricyclic architectures and to revise the structure of the natural product.
Wei Cao, Alicia Ross, Jean‐Pierre Baltaze, Régis Guillot, Menglin Xu, Rongzhen Qin, Bingcheng Yang, Isabel Wong, Katayoon Formul, Cyrille Kouklovsky, Dean J. Tantillo, Vincent Gandon, Guillaume Vincent   +12 more
wiley   +2 more sources

Comparative Studies on Conventional and Ultrasound-Assisted Synthesis of Novel Homoallylic Alcohol Derivatives Linked to Sulfonyl Dibenzene Moiety in Aqueous Media

Journal of Chemistry, 2013
Novel homoallylic alcohols incorporating sulfone moieties were synthesized by the treatment of different carbonyl compounds with allylic bromides in aqueous media via sonochemical Barbier-type reaction conditions.
Mohamed F. Mady, Ahmed A. El-Kateb, Ibrahim F. Zeid, Kåre B. Jørgensen   +3 more
doaj   +1 more source

Indium-Mediated Allylation of Carbonyl Compounds in Ionic Liquids: Effect of Salts in Ionic Liquids

Molecules, 2018
The In-mediated allylation of carbonyl compounds can be performed in various types of solvents including ionic liquids. However, we have found that in [bmim][BF4] (where bmim = 1-butyl-3-methylimidazolium), the In-mediated coupling of crotyl bromide with
Tsunehisa Hirashita, Fusako Takahashi, Takayuki Noda, Yuji Takagi, Shuki Araki   +4 more
doaj   +1 more source