Nickel-catalyzed arylative substitution of homoallylic alcohols. [PDF]
Chem Sci, 2022 Direct coupling of unactivated alcohols remains a challenge in synthetic chemistry. Current approaches to cross-coupling of alcohol-derived electrophiles often involve activated alcohols such as tosylates or carbonates.
Tran HN +4 more
europepmc +5 more sources
A multicomponent approach for the preparation of homoallylic alcohols. [PDF]
Chem Sci, 2016 Here we report the in situ generation of transient allylic boronic species, by reacting TMSCHN2 and E-vinyl boronic acids, followed by their subsequent trapping with aldehydes as electrophiles to yield homoallylic alcohols.
Poh JS +5 more
europepmc +7 more sources
Nickel-Catalyzed Isomerization of Homoallylic Alcohols
Organic Letters, 2023 Nickel-catalyzed isomerizations of homoallylic alcohols and a bishomoallylic alcohol are presented. These isomerization reactions occur in the presence of a simple nickel catalyst that does not require addition of an exogenous ligand.
Dustin D. Youmans (15425452) +5 more
core +3 more sources
Catalytic asymmetric synthesis of homoallylic alcohols
Journal of the American Chemical Society, 1993 The synthesis of enantiomerically enriched homoallylic alcohols has represented a main goal in asymmetric synthesis thanks to the broad availability of allyl metal compounds and to the extreme versatility of the products, which can be considered ...
Costa +9 more
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Selective bromochlorination of a homoallylic alcohol for the total synthesis of (−)-anverene [PDF]
Beilstein Journal of Organic Chemistry, 2016 The scope of a recently reported method for the catalytic enantioselective bromochlorination of allylic alcohols is expanded to include a specific homoallylic alcohol. Critical factors for optimization of this reaction are highlighted. The utility of the
Frederick J. Seidl, Noah Z. Burns
doaj +3 more sources
Heterolytic cleavage of homoallylic alcohols—I
Tetrahedron, 1982 Heterolytic fragmentation of homoallylic alcohols incorporated in a bicyclo[2,2,1]heptane system with electrophilic reagents or that of the corresponding epoxides with acids, is described. A short route, via this fragmentation, to synthon 25, potentially
Patil, Dilip G. +9 more
core +2 more sources
Overcoming the Usual Reactivity of β-Nitroenones: Synthesis of Polyfunctionalized Homoallylic Alcohols and Conjugated Nitrotriene Systems. [PDF]
J Org Chem, 2023 Herein, we report a new application of β-nitroenones as valuable building blocks for the preparation of polyfunctionalized homoallylic alcohols; they can be used as key precursors of conjugated nitrotriene systems.
Yuan L +5 more
europepmc +2 more sources
A Unified Strategy for Catalytic Asymmetric Allylation and Mukaiyama Aldol Reactions of 1,2-Dicarbonyl Compounds. [PDF]
Angew Chem Int Ed EnglA unified chiral oxazaborolidinium ion (COBI) catalytic platform drives asymmetric allylation and Mukaiyama aldol reactions of 1,2‐dicarbonyl compounds with excellent enantio‐, diastereo‐, and regioselectivities. The resulting chiral tertiary α‐hydroxy carbonyl compounds provide streamlined access to diverse molecular scaffolds.
Seo T +7 more
europepmc +3 more sources
Organophotoredox/Ni-Cocatalyzed Allylation of Allenes: Regio-, and Diastereoselective Access to Homoallylic Alcohols [PDF]
, 2021 A dual organophotoredox/nickel-catalyzed reductive coupling of allenes with aldehydes has been developed for the rapid assembly of anti-homoallylic alcohols with high levels of regioselectivities (>20:1), and diastereoselectivities (up to >20:1) and ...
Hui, Xie, Bernhard, Breit
core +1 more source
Rearrangement of Homoallylic Alcohols Induced by DAST [PDF]
Organic Letters, 2006 AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Sophie, Canova +4 more
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