Results 1 to 10 of about 12,893 (216)

Total syntheses of the parvistemoline alkaloids enabled by stereocontrolled Ir/Pd-catalyzed allylic alkylation

Nature Communications
The functionalized polycycle with densely contiguous tertiary stereocenters is a formidable challenge in synthesizing the parvistemoline family of Stemona alkaloids.
Xiao Liang, Qian-Hui Ding, Jian-Ting Yang, Hua-Fei Yang, Yi Deng, Li Shi, Kun Wei, Yu-Rong Yang   +7 more
doaj   +1 more source

New Bicyclic Azalide Macrolides Obtained by Tandem Palladium Catalyzed Allylic Alkylation/Conjugated Addition Reaction

Molecules, 2022
Unprecedented tandem allylic alkylation/intermolecular Michael addition was used in the preparation of novel bicyclic azalides. NMR spectroscopy was used not only to unambiguously determine and characterize the structures of these unexpected products of ...
Sulejman Alihodžić, Hana Čipčić Paljetak, Ana Čikoš, Ivaylo Jivkov Elenkov   +3 more
doaj   +1 more source

Synthesis of indole-based propellane derivatives via Weiss–Cook condensation, Fischer indole cyclization, and ring-closing metathesis as key steps

Beilstein Journal of Organic Chemistry, 2013
A variety of highly functionalized indole-based [n.3.3]propellane derivatives is described. The synthesis of the propellane derivatives involves a Weiss–Cook condensation, a Fischer indole cyclization, and a ring-closing metathesis as key steps.
Sambasivarao Kotha, Ajay Kumar Chinnam, Arti Tiwari   +2 more
doaj   +1 more source

Studies towards the synthesis of hyperireflexolide A

Beilstein Journal of Organic Chemistry, 2018
The first approach to hyperireflexolide A, based on the synthesis of γ-lactone-fused cyclopentane 5, a functionalized key intermediate, is presented. Compound 5 is involved in hydrolysis, α-allylation at C-8 and α-methylation at C-10 stereoselectively ...
G. Hari Mangeswara Rao
doaj   +1 more source

Rh(II)/Pd(0) Dual Catalysis: Carbenoid N-H Insertion/Allylation Cascade Reaction to Construct Highly Functionalized and Polysubstituted Pyrrolidines

Molecules
In the category of drugs approved by the U.S. FDA, pyrrolidine is the most frequently used core of five-membered nonaromatic heterocycles containing nitrogen.
Maocheng Tang, Xianyan Jiao, Deping He, Ji-Xing Zhao, Ping Liu, Chun-Tian Li   +5 more
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APLICAÇÃO DE AMIDOXIMAS COMO CATALISADORES DA REAÇÃO DE ALILAÇÃO POR ALILTRIFLUOROBORATO DE POTÁSSIO EM MEIO BIFÁSICO

Química Nova
We describe the application of an amidoxime as catalyst in the synthesis of homoallylic alcohols from the allylation reaction of aldehydes with different features using potassium allyltrifluoroborate. The reaction was conducted with a catalytic amount of
Dmistocles de Andrade, João Rufino de Freitas Filho, Juliano Carlo Rufino Freitas   +2 more
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Reductively Stable Platinum Catalyst Enabling Metallaphotoredox Reductive Allylation of Ketones, Aldehydes, and Imines

ChemistryEurope
This work demonstrates the catalytic reductive allylation of ketones, aldehydes, and imines using a synergistic platinum/photoredox catalyst system. Notably, this method is applicable even to acetophenone derivatives, affording homoallylic alcohols that ...
Junpei Shimosato, Kousei Nishimura, Bunta Fukuyo, Yohei Shimizu, Masaya Sawamura, Yusuke Masuda   +5 more
doaj   +1 more source

Bi-mediated allylation of aldehydes in [bmim][Br]: a mechanistic investigation

Beilstein Journal of Organic Chemistry, 2018
The inexpensive room temperature ionic liquid (RTIL), [bmim][Br] has been found to be a superior medium for the Bi-mediated Barbier-type allylation of aldehydes compared to other conventional solvents.
Mrunesh Koli, Sucheta Chatterjee, Subrata Chattopadhyay, Dibakar Goswami   +3 more
doaj   +1 more source

Crystal structure of 1,3-diallyl-1,3,3a,4,7,7a-hexahydro-4,7-methano-2-benzothiophene 2,2-dioxide

Acta Crystallographica Section E, 2014
The title compound C15H20O2S, was identified as a product of diallylation of the meso-isomer of the corresponding norbornene sulfone, and it is an achiral compound.
Sambasivarao Kotha, Rama Gunta
doaj   +1 more source

Indium-mediated allylation in carbohydrate synthesis: A short and efficient approach towards higher 2-acetamido-2-deoxy sugars

Beilstein Journal of Organic Chemistry, 2014
Higher aminosugars are interesting targets in carbohydrate synthesis since these compounds play important roles in biological systems. However, their availability from natural sources is limited.
Christopher Albler, Ralph Hollaus, Hanspeter Kählig, Walther Schmid   +3 more
doaj   +1 more source