Results 1 to 10 of about 3,465 (163)

Application of Hosomi-Sakurai allylation reaction in total synthesis of biologically active natural products [PDF]

Frontiers in Chemistry
The Hosomi–Sakurai allylation reaction has been widely applied in the total synthesis of biologically active natural products, especially in synthesising complex polycyclic compounds containing multi-stereogenic centres since its discovery in 1976.
Justice Akwensi, Robert T. Kumah, Dorcas Osei-Safo, Richard K. Amewu   +3 more
doaj   +2 more sources

Copper-Catalyzed Enantioselective Allyl–Allyl Cross-Coupling [PDF]

Journal of the American Chemical Society, 2013
A Cu(I)-phosphoramidite-based catalytic system that allows asymmetric allyl-allyl cross-coupling with high enantioselectivity is reported. This transformation tolerates a large variety of functionalized substrates. The versatility of this new reaction is illustrated in the catalytic asymmetric synthesis of the Martinelline alkaloids chromene derivative
Hornillos, Valentin, Perez, Manuel, Fananas-Mastral, Martin, Feringa, Ben L.   +3 more
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Transition-metal-free allylation of 2-azaallyls with allyl ethers through polar and radical mechanisms

Nature Communications, 2021
Allylation of nucleophiles with less reactive electrophiles, such as carbonates, usually requires a transition-metal catalyst. Here, the authors show a transition-metal-free allylation strategy with allyl ether electrophiles to form homoallylic amine ...
Guogang Deng, Shengzu Duan, Jing Wang, Zhuo Chen, Tongqi Liu, Wen Chen, Hongbin Zhang, Xiaodong Yang, Patrick J. Walsh   +8 more
doaj   +1 more source

Synthesis of Novel Crown Ether-Squaramides and Their Application as Phase-Transfer Catalysts

Molecules, 2021
This work presents the synthesis of six new phase-transfer organocatalysts in which the squaramide unit is directly linked to the nitrogen atom of an aza-crown ether.
Zsuzsanna Fehér, Dóra Richter, Sándor Nagy, Péter Bagi, Zsolt Rapi, András Simon, László Drahos, Péter Huszthy, Péter Bakó, József Kupai   +9 more
doaj   +1 more source

DABCO-Catalyzed Mono-/Diallylation of N-Unsubstituted Isatin N,N′-Cyclic Azomethine Imine 1,3-Dipoles with Morita-Baylis-Hillman Carbonates

Molecules, 2023
Allylation of N-unsubstituted isatin N,N′-cyclic azomethine imines with Morita-Baylis-Hillman carbonates in the presence of 1–10 mol% DABCO in DCM at room temperature, rapidly gave N-allylated and N, β-diallylated isatin N,N′-cyclic azomethine imine 1,3 ...
Qiumi Wang, Sicheng Li, Guosheng Yang, Xinyu Zou, Xi Yin, Juhua Feng, Huabao Chen, Chunping Yang, Li Zhang, Cuifen Lu, Guizhou Yue   +10 more
doaj   +1 more source

Pd-Catalyzed Enantioselective Allyl−Allyl Cross-Coupling [PDF]

Journal of the American Chemical Society, 2010
The Pd-catalyzed cross-coupling of allylic carbonates and allylB(pin) is described. The regioselectivity of this reaction is sensitive to the bite angle of the ligand, with small-bite-angle ligands favoring the branched substitution product. This mode of regioselection is consistent with a reaction that operates by a 3,3' reductive elimination reaction.
Ping, Zhang, Laura A, Brozek, James P, Morken   +2 more
openaire   +2 more sources

Intramolecular Barbier reaction in water: cyclopentane and cyclohexane ring closure [PDF]

Journal of the Serbian Chemical Society, 2002
Zinc or indium promoted intramolecular Barbier reactions of aldehydes containing a suitably positioned allylic or propargylic halide unit afford unsaturated cyclic alcohols in moderate yields.
RADOMIR N. SAICIC, RADOMIR MATOVIC, ALEKSANDAR IVKOVIC   +2 more
doaj   +3 more sources

Copper(I)-catalyzed asymmetric 1,6-conjugate allylation

Nature Communications, 2020
Catalytic asymmetric conjugate allylation of unsaturated carbonyl compounds is usually difficult to achieve due to competing 1,2-addition. Here, the authors report a copper(I)-catalyzed asymmetric 1,6-conjugate allylation of 2,2-dimethyl-6-alkenyl-4H-1,3-
Chang-Yun Shi, Zhi-Zhou Pan, Ping Tian, Liang Yin   +3 more
doaj   +1 more source

A Green Approach for Allylations of Aldehydes and Ketones: Combining Allylborate, Mechanochemistry and Lanthanide Catalyst

Molecules, 2016
Secondary and tertiary alcohols synthesized via allylation of aldehydes and ketones are important compounds in bioactive natural products and industry, including pharmaceuticals.
Viviane P. de Souza, Cristiane K. Oliveira, Thiago M. de Souza, Paulo H. Menezes, Severino Alves, Ricardo L. Longo, Ivani Malvestiti   +6 more
doaj   +1 more source

Generation and Reactions of ε-Carbonyl Cations via Group 13 Catalysis

Molecules, 2022
The generation of ε-carbonyl cations and their reactions with nucleophiles is accomplished readily without transition metal cation stabilization, using the ε-bromide dienoate or dienone starting materials and GaCl3 or InCl3 catalysis.
Page M. Penner, James R. Green
doaj   +1 more source