Zinc-Catalyzed β-Allylation of Cyclopropanols via Enolized Homoenolate [PDF]
, 2021 We report herein a zinc-catalyzed β-allylation of cyclopropanols with Morita–Baylis–Hillman (MBH) carbonates with retention of the cyclopropane ring.
Naohiko, Yoshikai, Yoshiya, Sekiguchi
core +2 more sources
Catalytic Asymmetric Defluorinative Allylation of Silyl Enol Ethers [PDF]
, 2023 The stereocontrolled installation of alkyl fragments at the alpha position of ketones is a fundamental yet unresolved transformation in organic chemistry.
Albert, Moyano +3 more
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Organophotoredox/Ni-Cocatalyzed Allylation of Allenes: Regio-, and Diastereoselective Access to Homoallylic Alcohols [PDF]
, 2021 A dual organophotoredox/nickel-catalyzed reductive coupling of allenes with aldehydes has been developed for the rapid assembly of anti-homoallylic alcohols with high levels of regioselectivities (>20:1), and diastereoselectivities (up to >20:1) and ...
Hui, Xie, Bernhard, Breit
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Latent Pronucleophiles in Lewis Base Catalysis: Enantioselective Allylation of Silylated Stabilized Carbon Nucleophiles with Allylic Fluorides [PDF]
, 2023 Lewis base catalyzed allylations of C-centered nucleophiles have been largely limited to the niche substrates with acidic C-H substituted with C-F bonds at the stabilized carbanionic carbon.
Markus, Lange +4 more
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Sustainability and efficiency assessment of lignin-derived phenolic synthons’ allylation: in solution versus ball-milling [PDF]
, 2022 Allylation of phenols, a widely used reaction in multistep synthetic pathways, was herein investigated using mechanochemistry. This synthesis was first optimized on vanillin by varying key parameters including both chemical (e.g., stoichiometry, reaction
Sami, FADLALLAH +5 more
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Enantioselective Allylation from Allene, a Petroleum Cracking Byproduct [PDF]
, 2018 Allene (C3H4) gas is produced and separated on million-metric-ton scale per year during petroleum refining but is only rarely employed in chemical manufacturing. Meanwhile, the addition of an allyl group (C3H5) to ketone-containing molecules is among the
Yujing, Zhou +3 more
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Rapid Decarboxylative Allylation of Nitroalkanes
, 2016 Allyl nitroacetates undergo decarboxylative allylation to provide tertiary nitroalkanes in high yield. Moreover, the transformations are complete within several minutes under ambient conditions. High yields result because O-allylation of the intermediate
Alexander J. Grenning (2167951) +1 more
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Highly Diastereo- and Enantioselective Allylboration of Aldehydes using alpha-Substituted Allyl/Crotyl Pinacol Boronic Esters via in Situ Generated Borinic Esters [PDF]
, 2013 Readily available, alpha-substituted allyl/crotyl pinacol boronic esters often give low E/Z selectivity (with Z favored) in reactions with aldehydes. We found that addition of nBuLi to the pinacol boronic ester followed by trapping of the alkoxide with ...
Jack L.‐Y. Chen +10 more
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Angewandte Chemie, EarlyView.The first catalytic asymmetric formal [3+2] cycloaddition of allylsilanes delivers cis‐2,5‐disubstituted tetrahydrofuran‐3‐ones that serve as versatile intermediates for the synthesis of diverse bioactive scaffolds. ABSTRACT A formal [3+2] cycloaddition via cyclization/1,2‐hydride shift initiated by nucleophilic attack of allylsilanes has been ...
Hosung Lee +5 more
wiley +2 more sources
Modular allylation of C(sp3)−H bonds by combining decatungstate photocatalysis and HWE olefination in flow [PDF]
, 2021 The late-stage introduction of allyl groups provides an opportunity to synthetic organic chemists for subsequent diversification, providing rapid access to new chemical space.
Timothy, Noel +4 more
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