Results 61 to 70 of about 108,077 (187)

Aqueous Barbier Allylation of Aldehydes Mediated by Tin

Molecules, 2007
The aqueous tin-mediated Barbier reaction affords good to excellent yields and moderate syn diastereoselectivity under basic and acidic conditions. The high yields and stereoselectivity observed in the case of o-substituted aldehydes suggest a cyclic ...
Ivani Malvestiti, Lothar W. Bieber, Marcelo Navarro, Fernando Hallwass, Lívia N. Cavalcanti, Maria Ester S. B. Barros, Dimas J. P. Lima, Ricardo L. Guimarães   +7 more
doaj   +1 more source

Alkoxyallenes in Modern Synthesis: Reactivity, Catalysis, and Complexity Generation

Advanced Synthesis &Catalysis, Volume 368, Issue 17, 1 September 2026.
The last decade has witnessed a remarkable transformation in alkoxyallene chemistry. Although historically employed as synthetic equivalents of acrolein or as versatile 3C synthons, alkoxyallenes are now increasingly recognized as highly adaptable platforms for synthetic design.
A. Lanfranco, M. Rusconi, J. Saglietto, P. Renzi, A. Deagostino, E. Azzi   +5 more
wiley   +1 more source

Flipping the Card With Enantiodivergent Organocatalysis

Chemistry – A European Journal, Volume 32, Issue 29, 7 August 2026.
This minireview elaborates on recent organocatalytic strategies for achieving enantiodivergence—the ability to access both product enantiomers using a single chiral catalyst. It highlights how achiral stimuli, such as solvent polarity and chemical additives, along with minimal catalyst modifications, trigger stereochemical inversions in reactions ...
Debora Iapadre, Alessio Carioscia, Alessandro Brusa, Armando Carlone   +3 more
wiley   +1 more source

Catalyst-Controlled Wacker-Type Oxidation of Homoallylic Alcohols in the Absence of Protecting Groups

, 2016
Homoallylic alcohols are oxidized to β-hydroxy ketones using a TBHP-mediated Pd-catalyzed Wacker-type oxidation. The use of a bidentate ligand, quinoline-2-oxazoline (Quinox), and TBHP(aq) as the terminal oxidant provides good yields of the desired ...
Brian W. Michel (1340532), Matthew S. Sigman (1306671), Jessica R. McCombs (2202625)   +2 more
core   +1 more source

Metal free synthesis of homoallylic alcohols promoted by ultrasound

Ultrasonics Sonochemistry, 2014
The use of ultrasound irradiation to promote the allylation of aldehydes containing different functionalities with potassium allyltrifluoroborates is described. The method features the use of a minimum amount of acetone as solvent, without any other catalyst or promoter.
Jucleiton José R, Freitas, Túlio R, Couto, Italo H, Cavalcanti, Juliano C R, Freitas, Roberta A, Oliveira, Paulo H, Menezes   +5 more
openaire   +2 more sources

A Modular Approach to Polyketide Building Blocks:  Cycloadditions of Nitrile Oxides and Homoallylic Alcohols

, 2016
A general approach to the diastereoselective synthesis of Δ2-isoxazolines via magnesium-mediated, hydroxyl-directed diastereoselective nitrile oxide cycloadditions of homoallylic alcohols and monoprotected homoallylic diols is disclosed. A broad spectrum
Nina Lohse-Fraefel (2683540), Erick M. Carreira (1330920)   +1 more
core   +1 more source

A modular approach to polyketide building blocks: cycloadditions of nitrile oxides and homoallylic alcohols.

, 2005
A general approach to the diastereoselective synthesis of Delta(2)-isoxazolines via magnesium-mediated, hydroxyl-directed diastereoselective nitrile oxide cycloadditions of homoallylic alcohols and monoprotected homoallylic diols is disclosed.
Carreira EM, Lohse-Fraefel N
core   +1 more source

Catalytic Regioselective Isomerization of 2,2‐Disubstituted Oxetanes to Homoallylic Alcohols

Angewandte Chemie, 2020
AbstractThe selective isomerization of strained heterocyclic compounds is an important tool in organic synthesis. An unprecedented regioselective isomerization of 2,2‐disubstituted oxetanes into homoallylic alcohols is described. The use of tris(pentafluorophenyl)borane (B(C6F5)3), a commercially available Lewis acid was key to obtaining good yields ...
Albert Cabré, Sergi Rafael, Giuseppe Sciortino, Gregori Ujaque, Xavier Verdaguer, Agustí Lledós, Antoni Riera   +6 more
openaire   +3 more sources

3-Methyl-2-((methylthio)methyl)but-2-enal

Molbank
During the Swern oxidation of 3-methylbut-3-en-1-ol, an unexpected C-C bond formation product, 3-methyl-2-(methylthio)but-2-enal, was obtained. Its structure was characterized using 1H-NMR, 13C-NMR, and HRMS.
Huaxuan Zhang, Xingang Xie
doaj   +1 more source

Photooxidation of 18‐Carbon Polyunsaturated Fatty Acids to Prepare Mono‐Hydroxylated Octadecanoids

Lipids, Volume 61, Issue 4, Page 447-458, July 2026.
We developed a fast and simple one‐step synthetic strategy to produce mono‐hydroxylated metabolites based on the photosensitized oxidation of 18‐carbon polyunsaturated fatty acids (PUFAs). This approach could likely be extended to other PUFAs, suggesting that photosensitized oxidation could be employed to rapidly prepare hydroperoxides from multiple ...
Johanna Revol‐Cavalier, Mats Hamberg, Craig E. Wheelock   +2 more
wiley   +1 more source