China precision nutrition and health: knowledge, attitude, and practice real-world study (CPNAS): a cross-sectional analysis of the association between serum vitamin A and homocysteine levels in rural middle-aged and elderly populations in China [PDF]
Nutrition JournalBackground Homocysteine levels are closely associated with overall health. An elevation in homocysteine can lead to a variety of health issues and is influenced by vitamins B12, B6, and folic acid.
Ning Chen +14 more
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Clinics in Laboratory Medicine, 2006 Elevated homocysteine levels are associated with a variety of vascular diseases. Specifically, hyperhomocysteinemia is a risk factor for coronary artery disease, cerebrovascular disease, and peripheral arterial disease. Laboratory-based strategies for its detection and quantification have evolved to meet the increasing need for accuracy in risk ...
Bradley A, Maron, Joseph, Loscalzo
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Homocysteine Metabolism in Pregnancy and Developmental Impacts
Frontiers in Cell and Developmental Biology, 2022 Homocysteine is a metabolite generated by methionine cycle metabolism, comprising the demethylated derivative of methionine. Homocysteine can be metabolised by the transsulphuration pathway to cystathionine, which requires vitamin B6, or can undergo ...
Stephen W. D’Souza, Jocelyn D. Glazier
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Ability of dietary factors to affect homocysteine levels in mice: a review
Nutrition & Metabolism, 2021 Homocysteine is associated with several diseases, and a series of dietary factors are known to modulate homocysteine levels. As mice are often used as model organisms to study the effects of dietary hyperhomocysteinemia, we collected data about ...
Christine Brütting +3 more
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Homocysteine levels correlate with AVSS-RigiScan test parameters in men with erectile dysfunction
Basic and Clinical Andrology, 2023 Background Although elevated homocysteine levels have been shown to affect penile erection, the relationship between homocysteine and erection at the tip or base of the penis has not been extensively studied.
Xin Qian +5 more
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The International Journal of Biochemistry & Cell Biology, 2000 Homocysteine does not occur in the diet but it is an essential intermediate in normal mammalian metabolism of methionine. Each compound, methionine or homocysteine, is the precursor of the other. Similarly, the synthesis of one is the mechanism for the detoxification of the other.
J D, Finkelstein, J J, Martin
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Homocysteine inhibits hepatocyte proliferation via endoplasmic reticulum stress. [PDF]
PLoS ONE, 2013 Homocysteine is an independent risk factor for coronary, cerebral, and peripheral vascular diseases. Recent studies have shown that levels of homocysteine are elevated in patients with impaired hepatic function, but the precise role of homocysteine in ...
Xue Yu +4 more
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Elevated plasma homocysteine upon ischemic stroke is associated with increased long-term mortality in women. [PDF]
PLoS ONE, 2017 Ischemic stroke is a leading cause of death worldwide, despite preventive and therapeutic advances during the last twenty years. Blood-borne biomarkers have been studied in association to short- and long-term outcome, in order to investigate possible ...
Ioanna Markaki +3 more
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Apoptosis of bone marrow mesenchymal stem cells caused by homocysteine via activating JNK signal. [PDF]
PLoS ONE, 2013 Bone marrow mesenchymal stem cells (BMSCs) are capable of homing to and repair damaged myocardial tissues. Apoptosis of BMSCs in response to various pathological stimuli leads to the attenuation of healing ability of BMSCs.
Benzhi Cai +11 more
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Role of homocysteine in the development and progression of Parkinson’s disease
Annals of Clinical and Translational Neurology, 2020 Homocysteine is an essential intermediate product of biochemical reactions that is present in various tissues of the human body. Homocysteine may be associated with the development and progression of Parkinson’s disease.
Xiaoyan Fan +6 more
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