Results 11 to 20 of about 90,248 (215)

Therapeutical approach to plasma homocysteine and cardiovascular risk reduction

Therapeutics and Clinical Risk Management, 2008
Marcello Ciaccio, Giulia Bivona, Chiara BelliaDepartment of Medical Biotechnologies and Forensic Medicine, Faculty of Medicine, University of Palermo, ItalyAbstract: Homocysteine is a sulfur-containing aminoacid produced during metabolism of methionine ...
Marcello Ciaccio, Giulia Bivona, Chiara Bellia   +2 more
doaj   +1 more source

Homocysteine And Stroke

Annals of Indian Academy of Neurology, 2004
In recent years, a great deal of attentions has been focused on the role of homocysteine, a sulfur-containing amino acid, in the etiopathogenesis of atherothromobtic vascular disease.
Nagaraja D, Christopher Ritha
doaj   +1 more source

Plasma homocysteine, measurement and clinical application

, 2006
Raised plasma homocysteine (Hcy) levels have been cited as a major risk factor for several vascular disorders. Yet hyperhomocysteinaemia is easily treated through dietary intervention and vitamin supplementation.
Hill, D. M.
core   +7 more sources

TNF receptor–related factor 3 inactivation promotes the development of intrahepatic cholangiocarcinoma through NF‐κB‐inducing kinase–mediated hepatocyte transdifferentiation

Hepatology, EarlyView., 2022
Abstract Background and Aims Intrahepatic cholangiocarcinoma (ICC) is a deadly but poorly understood disease, and its treatment options are very limited. The aim of this study was to identify the molecular drivers of ICC and search for therapeutic targets.
Yuto Shiode, Takahiro Kodama, Satoshi Shigeno, Kazuhiro Murai, Satoshi Tanaka, Justin Y. Newberg, Jumpei Kondo, Shogo Kobayashi, Ryoko Yamada, Hayato Hikita, Ryotaro Sakamori, Hiroshi Suemizu, Tomohide Tatsumi, Hidetoshi Eguchi, Nancy A. Jenkins, Neal G. Copeland, Tetsuo Takehara   +16 more
wiley   +1 more source

Proteogenomic characterization of cholangiocarcinoma

Hepatology, EarlyView., 2022
Proteogenomic characterization of cholangiocarcinoma with therapeutic strategies Abstract Background and Aims Cholangiocarcinoma (CCA) is a highly heterogeneous cancer with limited understanding and few effective therapeutic approaches. We aimed at providing a proteogenomic CCA characterization to inform biological processes and treatment ...
Mengjie Deng, Peng Ran, Lingli Chen, Yunzhi Wang, Zixiang Yu, Ke Cai, Jinwen Feng, Zhaoyu Qin, Yanan Yin, Subei Tan, Yang Liu, Chen Xu, Guoming Shi, Yuan Ji, Jian‐Yuan Zhao, Jian Zhou, Jia Fan, Yingyong Hou, Chen Ding   +18 more
wiley   +1 more source

Influence of hyperhomocysteinemia on the cellular redox state - Impact on homocysteine-induced endothelial dysfunction [PDF]

, 2003
Hyperhomocysteinemia is an independent risk factor for the development of atherosclerosis. An increasing body of evidence has implicated oxidative stress as being contributory to homocysteines deleterious effects on the vasculature.
Keaney, John F., Weiss, Norbert, Postea, Otilia, Heydrick, Stanley J., Keller, Christiane, Loscalzo, Joseph   +5 more
core   +1 more source

Do dietary patterns in older men influence change in homocysteine through folate fortification? The Normative Aging Study [PDF]

, 2009
Objective We aimed to describe the difference in B-vitamin intake and in plasma B-vitamin and homocysteine concentrations before and after folic acid fortification, in relation to dietary patterns. Design The Normative Aging Study (NAS) is a longitudinal
Groot, C.P.G.M., de, Spiro, A., Kromhout, D., Tucker, K.L., Staveren, W.A., van, Knoops, K.T.B.   +5 more
core   +1 more source

Creutzfeldt-Jakob disease and homocysteine levels in plasma and cerebrospinal fluid [PDF]

, 2005
Background: There is evidence that homocysteine contributes to various neurodegenerative disorders. Objective: To assess the values of homocysteine in patients with Creutzfeldt-Jakob disease (CJD) in both cerebrospinal fluid (CSF) and plasma.
Bleich, S., Kropp, S., Wiltfang, J., Zerr, Inga, Zerr, I., Kretzschmar, Hans A., Kropp, Silke, Otto, Markus, Wiltfang, Jens, Bleich, Stefan   +9 more
core   +1 more source

Effects of homocysteine lowering with B vitamins on cognitive aging: meta-analysis of 11 trials with cognitive data on 22,000 individuals. [PDF]

, 2014
BACKGROUND: Elevated plasma homocysteine is a risk factor for Alzheimer disease, but the relevance of homocysteine lowering to slow the rate of cognitive aging is uncertain.
Hankey, G.J., Lewerin, Catharina,, Sarah Parish, Eussen, Simone J. P. M., Dangour, A. D., Halsey, Jim, Bennett, Derrick, Lewington, S., David J Stott, Lewerin, C., Dangour, Alan D, Bennett, D., Graeme J Hankey, B-Vitamin Treatment Trialists’ Collaboration, Dangour, A.D., Eussen, Simone JPM, Lonn, E., Armitage, J., Spence, J.D., Francine Grodstein, Hankey, G. J., Parish, Sarah, Galan, P., Eussen, Sjpm, Catharina Lewerin, Alan D Dangour, de Groot, L.C., Parish, S., Eva Lonn, Hankey, Graeme J., Clarke, Robert, Halsey, J., Rory Collins, Derrick Bennett, Spence, J. D., Hankey, Graeme J, Simone JPM Eussen, Spence, J. David, Collins, Rory, Sarah Lewington, Stott, David J, Armitage, Jane, Stott, D. J., Lewington, Sarah, Eussen, S.J., Murray Skeaff, Lewerin, Catharina, Clarke, R., Robert Clarke, J David Spence, Grodstein, Francine, Spence, J David, Pilar Galan, Jim Halsey, Eussen, S.J.P.M.; id_orcid, Jane Armitage, Lonn, Eva, Galan, Pilar, Collins, R., Stott, David J., Groot, C.P.G.M., de, Dangour, Alan D., Grodstein, F., Skeaff, M., de Groot, Lisette C, Eussen, S.J.P.M., Lisette C de Groot, de Groot, L. C., de Groot, Lisette C., Stott, D.J., Skeaff, Murray   +70 more
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Homocysteine-induced endoplasmic reticulum stress.

, 2022
(A-D) SHY5Y-Ob-R cells were treated with homocysteine (Hcy), methionine (Met), and cysteine (Cys) for 4 and 8 hours at 10 mM, and the expression level of ER stress response gene, HERP, was analyzed by Dunnett test. *p 0.05, n = 5.
Michiko Yoshii (14253351), Arini Isnani Preninka (14253342), Kyosuke Yazawa (14253348), Toru Hosoi (154313), Yuhki Yanase (3960317), Ralf Jockers (245630), Julie Dam (8208489), Karen Kuriya (14253345), Koichiro Ozawa (154324)   +8 more
core   +1 more source