Results 11 to 20 of about 87,836 (275)
Homocysteine-induced endothelial dysfunction through mediating endoplasmic reticulum stress [PDF]
Journal of International Medical ResearchObjective Endothelial dysfunction is a key pathological process in cardiovascular and cerebrovascular diseases. Herein, we aimed to investigate the effect of homocysteine on endoplasmic reticulum stress in a model of endothelial dysfunction, focusing on ...
Xiaoxue Zhang +6 more
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Therapeutical approach to plasma homocysteine and cardiovascular risk reduction
Therapeutics and Clinical Risk Management, 2008 Marcello Ciaccio, Giulia Bivona, Chiara BelliaDepartment of Medical Biotechnologies and Forensic Medicine, Faculty of Medicine, University of Palermo, ItalyAbstract: Homocysteine is a sulfur-containing aminoacid produced during metabolism of methionine ...
Marcello Ciaccio +2 more
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Plasma homocysteine, measurement and clinical application
, 2006 Raised plasma homocysteine (Hcy) levels have been cited as a major risk factor for several vascular disorders. Yet hyperhomocysteinaemia is easily treated through dietary intervention and vitamin supplementation.
Hill, D. M.
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Clinics in Laboratory Medicine, 2006 Elevated homocysteine levels are associated with a variety of vascular diseases. Specifically, hyperhomocysteinemia is a risk factor for coronary artery disease, cerebrovascular disease, and peripheral arterial disease. Laboratory-based strategies for its detection and quantification have evolved to meet the increasing need for accuracy in risk ...
Bradley A, Maron, Joseph, Loscalzo
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Ability of dietary factors to affect homocysteine levels in mice: a review
Nutrition & Metabolism, 2021 Homocysteine is associated with several diseases, and a series of dietary factors are known to modulate homocysteine levels. As mice are often used as model organisms to study the effects of dietary hyperhomocysteinemia, we collected data about ...
Christine Brütting +3 more
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Homocysteine inhibits hepatocyte proliferation via endoplasmic reticulum stress. [PDF]
PLoS ONE, 2013 Homocysteine is an independent risk factor for coronary, cerebral, and peripheral vascular diseases. Recent studies have shown that levels of homocysteine are elevated in patients with impaired hepatic function, but the precise role of homocysteine in ...
Xue Yu +4 more
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Homocysteine Metabolism in Pregnancy and Developmental Impacts
Frontiers in Cell and Developmental Biology, 2022 Homocysteine is a metabolite generated by methionine cycle metabolism, comprising the demethylated derivative of methionine. Homocysteine can be metabolised by the transsulphuration pathway to cystathionine, which requires vitamin B6, or can undergo ...
Stephen W. D’Souza, Jocelyn D. Glazier
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International Journal of Molecular Sciences, 2023 Elevated levels of homocysteine (Hcy), a non-proteinogenic amino acid, may lead to a host of manifestations across the biological systems, particularly the nervous system. Defects in Hcy metabolism have been associated with many neurodegenerative diseases including glaucoma, i.e., the leading cause of blindness. However, the pathophysiology of elevated
Joshua Washington +2 more
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Homocysteine levels correlate with AVSS-RigiScan test parameters in men with erectile dysfunction
Basic and Clinical Andrology, 2023 Background Although elevated homocysteine levels have been shown to affect penile erection, the relationship between homocysteine and erection at the tip or base of the penis has not been extensively studied.
Xin Qian +5 more
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The International Journal of Biochemistry & Cell Biology, 2000 Homocysteine does not occur in the diet but it is an essential intermediate in normal mammalian metabolism of methionine. Each compound, methionine or homocysteine, is the precursor of the other. Similarly, the synthesis of one is the mechanism for the detoxification of the other.
J D, Finkelstein, J J, Martin
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