Results 41 to 50 of about 87,836 (275)

Association Between Homocysteine and Vascular Calcification Incidence, Prevalence, and Progression in the MESA Cohort

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background While elevated homocysteine has been associated with calcification in several studies, its importance as a cardiovascular risk factor remains unclear.
Amy B. Karger, Brian T. Steffen, Sarah O. Nomura, Weihua Guan, Parveen K. Garg, Moyses Szklo, Matthew J. Budoff, Michael Y. Tsai   +7 more
doaj   +1 more source

Homocysteine: A Potential Common Route for Cardiovascular Risk and DNA Methylation in Psoriasis

Chinese Medical Journal, 2017
Objective: Homocysteine is a sulfur-containing amino acid with potential clinical significance. Abnormal homocysteine levels have been found in patients with psoriasis.
Wen-Ming Wang, Hong-Zhong Jin
doaj   +1 more source

The Homocysteine Paradox [PDF]

Arteriosclerosis, Thrombosis, and Vascular Biology, 2008
There is little doubt that elevation of plasma total homocysteine is associated with increased cardiovascular risk. Over the past 2 decades, many large prospective studies have established that hyperhomocysteinemia predicts for an increased relative risk of coronary events, stroke, venous thromboembolism, and death.1,2 Hyperhomocysteinemia also has ...
Roman N, Rodionov, Steven R, Lentz
openaire   +2 more sources

Vitamin B-12 deficiency stimulates osteoclastogenesis via increased homocysteine and methylmalonic acid [PDF]

, 2009
The risk of nutrient deficiencies increases with age in our modern Western society, and vitamin B(12) deficiency is especially prevalent in the elderly and causes increased homocysteine (Hcy) and methylmalonic acid (MMA) levels.
Bravenboer, N., Vaes, Bart L T, Vaes, B.L.T., Everts, V., Wilma T. Steegenga, Bravenboer, Nathalie, Steegenga, W.T., Lute, Carolien, Carolien Lute, de Groot, L.C.P.G.M., Müller, M.R., Henk J. Blom, de Groot, C.P.G.M., Muller, M., Dhonukshe-Rutten, R.A.M., de Groot, Lisette C P G M, Dhonukshe-Rutten, R.A., Bart L. T. Vaes, Teun J. de Vries, Blom, Henk J, Nathalie Bravenboer, Groot, L.C.P.G.M. de, de Vries, Teun J, Müller, Michael, Everts, Vincent, Rosalie A. Dhonukshe-Rutten, Michael Müller, de Vries, T.J., Lisette C. P. G. M. de Groot, Dhonukshe-Rutten, Rosalie A, Steegenga, Wilma T, Groot, C.P.G.M., de, Lute, C., Vries, T. J., Blom, H.J., Everts, V, Vries, T.J., de, Vincent Everts   +37 more
core   +2 more sources

Nonnative Thiol and Aniline Methylation, Including Enantioselective Dithiol Desymmetrization, by Multicomponent Cobamide‐Dependent Methyltransferases Using Unactivated Methyl Donors

Angewandte Chemie, EarlyView.
Mixed MtaABC/MtgABC methyltransferase systems were developed for non‐native thiol and aniline methylation using the unactivated methyl donors methanol and glycine betaine. The platform enabled site‐selective and enantioselective methylation with turnover number up to 6000, representing the first enantioselective non‐native catalysis by cobamide ...
Amardeep Kumar, Osman Ishag Adam, Paras Gupta, Jared C. Lewis   +3 more
wiley   +2 more sources

High‐Tg Polythioesters From Isomerization Ring‐Opening Polymerization of a Renewable Oxanorbornane‐Fused Thionolactone

Angewandte Chemie, EarlyView.
A biobased tricyclic thionolactone undergoes selective isomerization ring‐opening polymerization to yield a high‐molecular‐weight polythioester with an exceptionally high Tg of 171°C, exceeding that of the analogous polyester. The polythioester efficiently depolymerizes through backbiting, while its hydrolysis and methanolysis reveal the critical ...
Eva Harsevoort, Henk‐Jan Akkerman, Martin Lutz, Arnaud Thevenon, Pieter C. A. Bruijnincx   +4 more
wiley   +2 more sources

Homocysteine causes neuronal leptin resistance and endoplasmic reticulum stress

PLoS ONE, 2022
Abnormally high serum homocysteine levels have been associated with several disorders, including obesity, cardiovascular diseases or neurological diseases.
Arini Isnani Preninka, Karen Kuriya, Kyosuke Yazawa, Michiko Yoshii, Yuhki Yanase, Ralf Jockers, Julie Dam, Toru Hosoi, Koichiro Ozawa   +8 more
doaj  

Homocysteine homeostasis and betaine-homocysteine S-methyltransferase expression in the brain of hibernating bats. [PDF]

PLoS ONE, 2013
Elevated homocysteine is an important risk factor that increases cerebrovascular and neurodegenerative disease morbidity. In mammals, B vitamin supplementation can reduce homocysteine levels.
Yijian Zhang, Tengteng Zhu, Lina Wang, Yi-Hsuan Pan, Shuyi Zhang   +4 more
doaj   +1 more source

Potential Antioxidative Activity of Homocysteine in Erythrocytes under Oxidative Stress

Antioxidants, 2023
Homocysteine is an amino acid containing a free sulfhydryl group, making it probably contribute to the antioxidative capacity in the body. We recently found that plasma total homocysteine (total-Hcy) concentration increased with time when whole blood ...
Mingxin Ye, Hui Li, Hongjun Luo, Yongyin Zhou, Wenhong Luo, Zhexuan Lin   +5 more
doaj   +1 more source

Plasma homocysteine, folate and vitamin B(12) compared between rural Gambian and UK adults. [PDF]

, 2006
The disease risk indicator plasma total homocysteine (tHcy) is influenced by genetic and environmental factors, including folate and vitamin B(12) status. Little is known about the determinants of tHcy in rural West Africa.
Moore, Sophie E, Mansoor, M Azam, Bates, Christopher J, Prentice, Andrew M   +3 more
core   +1 more source