Results 61 to 70 of about 57,118 (176)

Clinical outcomes of mitochondrial‐enhancing nutraceutical supplementation in psychiatric disorders: A systematic review

open access: yesGeneral Psychiatry, Volume 39, Issue 3, June 2026.
ABSTRACT Background Nutraceutical supplementation targeting mitochondrial function has been proposed as a beneficial therapeutic strategy to improve physical and mental health in psychiatric patients. Aims To summarise the results of studies evaluating nutraceutical supplementation targeting mitochondrial function in patients with psychiatric disorders.
Juan Tortajada   +9 more
wiley   +1 more source

Systemic Inflammation and Central Neuronal Damage: The Relationship Between Neutrophil‐to‐Lymphocyte Ratio and Neuron‐Specific Enolase in Acute Ischemic Stroke

open access: yesImmunity, Inflammation and Disease, Volume 14, Issue 6, June 2026.
ABSTRACT Background and Purpose The systemic inflammatory response, quantified by the neutrophil‐to‐lymphocyte ratio (NLR), and central neuronal injury, reflected by serum neuron‐specific enolase (NSE), are implicated in the pathogenesis of acute ischemic stroke (AIS).
Ning Rong   +8 more
wiley   +1 more source

Heme Metabolism‐Derived Carbon Monoxide Regulates Skeletal Muscle Function

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 3, June 2026.
ABSTRACT Background Heme oxygenases, HO‐1 (Hmox1) and HO‐2 (Hmox2), regulate skeletal muscle homeostasis by degrading heme and generating carbon monoxide (CO), a bioactive signalling molecule. Although HO‐1 is known to influence muscle fibre composition and mitochondrial function, the role of HO‐2 in activity‐dependent neuromuscular plasticity remains ...
Rodrigo W. Alves de Souza   +8 more
wiley   +1 more source

Venous Thromboembolism (VTE) Risk Stratification in Otolaryngology: Socioeconomic and Subspecialty Insights

open access: yesLaryngoscope Investigative Otolaryngology, Volume 11, Issue 3, June 2026.
ABSTRACT Objective Venous thromboembolism (VTE) is a leading cause of preventable perioperative mortality in otolaryngology, highlighting the urgent need for validated risk assessments such as the Caprini score to guide prophylaxis and enhance patient safety.
Corinne A. Pittman   +5 more
wiley   +1 more source

The Role of N6‐Methyladenosine Modification in Health and Disease

open access: yesMedComm, Volume 7, Issue 6, June 2026.
N6‐methyladenosine (m6A) is the most prevalent internal RNA modification in eukaryotes, acting as a pivotal epitranscriptomic regulator of RNA metabolism. This modification plays a dual role: it maintains physiological homeostasis under normal conditions but drives disease progression when dysregulated.
Linghuan Li   +6 more
wiley   +1 more source

Diabetic Peripheral Neuropathy: Molecular Staging, Risk Factors, Therapeutics, and Emerging Trends

open access: yesMed Research, Volume 2, Issue 2, Page 309-342, June 2026.
The heterogeneous landscape of DPN can be unified through a tripartite pathogenic model encompassing progressive stages of metabolic dysregulation, chronic inflammation, and overt neuronal damage. Within this framework, six clinical subtypes were identified, namely, hyperglycemia‐driven, dyslipidemia‐driven, inflammation‐driven, dysvascularity‐driven ...
Xiaofeng Dai, Mingze Tang
wiley   +1 more source

Oxidative Stress and DNA Epigenetic Modifications in Cancer: Mechanisms and Targeted Therapeutics

open access: yesMedComm – Oncology, Volume 5, Issue 2, June 2026.
Reactive oxygen species (ROS) modulate DNA methyltransferases (DNMTs), ten‐eleven translocation family proteins (TETs) and their cofactors, reshaping 5‐methylcytosine (5mC)/5‐hydroxymethylcytosine (5hmC)/5‐formylcytosine (5fC) landscapes and gene expression in cancer cells. In turn, epigenetic control of antioxidant and metabolic pathways feeds back on
Xishan Yang   +7 more
wiley   +1 more source

Predicting late radiation-associated neurocognitive and endocrine toxicity in patients with brain tumors. [PDF]

open access: yesJ Neurooncol
Tuohy K   +7 more
europepmc   +1 more source

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