ABSTRACT Statins, widely prescribed for cardiovascular prevention, have emerged as potential disease‐modifying agents in neurodegenerative disorders due to their pleiotropic effects on cholesterol metabolism, neuroinflammation, oxidative stress, and protein aggregation.
Luigi Maria Chiatto +7 more
wiley +1 more source
Multigene Screening of B-Vitamin Metabolism Pathways in Hypertensive Disorders of Pregnancy: Toward Precision Prenatal Care. [PDF]
Zhang T.
europepmc +1 more source
The Boruta‐XGBoost based risk prediction model, combined with SHAP interpretation, demonstrated high predictive accuracy and robust interpretability for forecasting hospital readmission or death during the vulnerable phase in elderly heart failure patients. This model can assist clinicians to identify high‐risk individuals, supporting clinical decision‐
Hao Luo +10 more
wiley +1 more source
Follicular fluid cytokine and homocysteine profiles in poor ovarian responders with and without sonographic endometrioma: A comparative study. [PDF]
Şanlı BE +5 more
europepmc +1 more source
This study integrated arterial stiffness with peripheral TCRβ repertoire and single‐cell transcriptomics in adults without cardiovascular disease, revealing a CD4+ T cell–driven “vascular immune remodeling” trajectory distinct from classical immunosenescence: increased TCR diversity, broad expansion of low‐frequency public clones and virus‐associated ...
Yu Miao +9 more
wiley +1 more source
Risk of Retinal Vein Occlusion in Patients With Vitamin B<sub>12</sub> Deficiency and Hyperhomocysteinemia: A Propensity-Matched Cohort Study Using TriNetX. [PDF]
Shmushkevich SB +10 more
europepmc +1 more source
Clinical Utility of Stillbirth Investigations in Australia: A Cohort Study
ABSTRACT Background Stillbirths impact over two million parents globally every year. Despite current knowledge, technology, and investigations, many stillbirths remain unexplained and are not fully investigated. An important step forward in addressing this gap is determining which investigations produce the highest utility in identifying the cause of ...
Tania Marsden +22 more
wiley +1 more source
Hyperhomocysteinemia as a potential risk factor for unexplained recurrent pregnancy loss: an exploratory case-control study at Damascus University Maternity Hospital. [PDF]
Ghanem L, Ali T.
europepmc +1 more source
ABSTRACT Carotid–femoral pulse‐wave velocity (cfPWV) is a marker of central arterial stiffness and an established predictor of cardiovascular risk in hypertension. Although elevated lipoprotein(a) [Lp(a)] concentrations and peripheral arterial disease (PAD) are associated with atherosclerotic cardiovascular disease, their independent associations with ...
Bibombe P. Mwipatayi +8 more
wiley +1 more source
Correlation of composite inflammatory indices and homocysteine with the severity of acute ischemic stroke: A retrospective study. [PDF]
Du Y, Yang F, Liu Y.
europepmc +1 more source

