Neurotoxic and neuroprotective effects of homocysteine and hydrogen sulfide
Homocysteine is a sulfhydryl-containing amino acid derived from methionine. The cellular concentration of homocysteine is regulated by two key pathways: remethylation back to methionine or transsulfuration to cysteine with simultaneous production of ...
G.F. Sitdikova +2 more
doaj
High paternal homocysteine causes ventricular septal defects in mouse offspring
Summary: Maternal hyperhomocysteinemia is widely considered as an independent risk of congenital heart disease (CHD). However, whether high paternal homocysteine causes CHD remains unknown.
Lian Liu +5 more
doaj +1 more source
PENGARUH PEMBERIAN FOLAT TERHADAP KADAR HOMOSISTEIN SERUM DAN MALONDIALDEHID PLASMA STUDI EKSPERIMENTAL PADA TIKUS SPRAGUE DAWLEY YANG DIINDUKSI STREPTOZOTOCIN [PDF]
Background: Diabetes mellitus (DM) associated with increased level and oxidative activity of homocystein (Hcy) that cause oxidative stress. Plasma malondialdehyde (MDA) known as a marker of oxidative stress.
Wahyuni, Emmy
core
Small Strokes, Big Impact: Excessive Mortality After Acute Ischemic Stroke in Parkinson's Disease
Abstract Background Acute ischemic stroke (AIS) in those with Parkinson's disease (PD) is a growing healthcare burden but mortality studies are significantly lacking. Objective To map short‐ and long‐term survival, stratified by relevant comorbidities and stroke characteristics.
Lee E. Neilson +3 more
wiley +1 more source
Homocysteine is an indirect metabolite of methionine metabolism, as well as of creatinine, and it plays an important role in many biochemical processes.
Eugenia Murawska-Ciałowicz
doaj
An inadequate folate status is associated with increased risk of anaemia and neural tube defects. In many countries a folate intake below recommendations has been reported for women in childbearing age.
Öhrvik, Veronica
core
One-carbon metabolism in cancer [PDF]
Cells require one-carbon units for nucleotide synthesis, methylation and reductive metabolism, and these pathways support the high proliferative rate of cancer cells.
AJ MacFarlane +55 more
core +1 more source
Homocysteine as a risk factor of ischemic heart disease development (review) [PDF]
Homocysteine is a product of methionine metabolism. Increased levels of homocysteine strengthen oxidizing stress, disturb endothelial function, raise arterial blood pressure and lead to thrombus formation.
Skvortsov Yu.l., Korolkova A.S.
doaj
Genetic Studies of Sulfadiazine-resistant and Methionine-requiring \u3cem\u3eNeisseria\u3c/em\u3e Isolated From Clinical Material [PDF]
Deoxyribonucleate (DNA) preparations were extracted from Neisseria meningitidis (four isolates from spinal fluid and blood) and N. gonorrhoeae strains, all of which were resistant to sulfadiazine upon primary isolation.
BROWN G. M. +35 more
core +2 more sources
A Comprehensive Review of the Genetic Etiology and Management of Orofacial Clefts
ABSTRACT Cleft lip (CL) and cleft palate (CP), collectively referred to as orofacial clefts (OFCs), are among the most common birth defects and can have significant effects on speech, nutrition, and physical and psychosocial development. Manifestation, classification, and treatment plans of OFCs are diverse and not standardized.
Emily Kim +3 more
wiley +1 more source

