Results 91 to 100 of about 61,908 (219)
Retinal Ganglion Cell Loss in Diabetes Associated with Elevated Homocysteine
A number of studies have suggested that homocysteine may be a contributing factor to development of retinopathy in diabetic patients based on observed correlations between elevated homocysteine levels and the presence of retinopathy.
Kenneth S. Shindler
doaj
Background Homocysteine levels are closely associated with overall health. An elevation in homocysteine can lead to a variety of health issues and is influenced by vitamins B12, B6, and folic acid.
Ning Chen +14 more
doaj +1 more source
Novel Amino Acid Changes Increase Phosphoenolpyruvate Carboxylase Output in planta
ABSTRACT Characterization of previously reported Arabidopsis mutants with increased aluminum (Al) resistance (alr) resulting from greater release of Al‐chelating malate identified three unique amino acid substitutions that each impacts PHOSPHOENOLPYRUVATE CARBOXYLASE 1, a key anaplerotic carbon fixation enzyme.
Jinrui Sheng +7 more
wiley +1 more source
Impact of systemic diseases on periodontal remodeling: Mechanisms, mediators, and clinical relevance
Abstract Background Periodontal remodeling is a continuous, adaptive process essential for maintaining the structural and functional integrity of periodontal tissues. While external factors such as bacterial biofilm, excessive forces, and poor oral hygiene are recognized triggers of periodontal pathologies, they do not fully explain their persistent ...
Michael Wolf +7 more
wiley +1 more source
CORRELATION BETWEEN TOTAL PLASMA HOMOCYSTEINE LEVEL AND GRADING OF CORONARY ARTERY DISEASE
Elevated total plasma homocysteine (tHcy) levels constitute a risk factor for coronary artery disease (CAD). A possible relationship was investigated between admission plasma homocysteine level and the angiographic severity and extension of coronary ...
S. J. Mirhoseini +6 more
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An eye on long‐duration spaceflight: Controversies, countermeasures and challenges
Abstract Space flight‐associated neuroocular syndrome (SANS) is a consequence of long‐duration space flight and is detected in two‐thirds of astronauts. In‐flight, this can cause a change in the refraction of the eyes, requiring graded hypermetropic ‘superfocus adjustable’ glasses, optic nerve head oedema and choroidal folds.
Vincent Wing Sum Ng +1 more
wiley +1 more source
Dietary interventions in acute kidney injury: From molecular mechanism to clinical trials
Abstract Ageing impairs renal resilience with an elevated risk of frequent and harmful acute kidney injury (AKI) that causes substantial morbidity and mortality among hospitalized patients. Since different damaging stimuli at the molecular, cellular and functional level contribute to this loss in kidney function, AKI's pathophysiology is heterogeneous ...
Felix C. Koehler +2 more
wiley +1 more source
Abstract Background Racehorses undergo profound physiological changes with training and competition, but current biomarkers inadequately capture the complex molecular dynamics of exercise. This study aimed to identify novel plasma biomarkers of training adaptation and peak load using high‐throughput proteomics.
Jowita Grzędzicka +4 more
wiley +1 more source
Ferroptosis is governed by the balance between reactive oxygen species (ROS)‐driven lipid peroxidation and a multi‐tiered antioxidant network. ROS sources include mitochondrial electron transport chain, voltage‐dependent anion channels, NADPH oxidases, and endoplasmic reticulum‐resident oxidoreductases, while antioxidant defenses span the primary GSH ...
Deepak K +5 more
wiley +1 more source
Assessment of serum homocysteine level and hyperhomocysteinaemia in the northern Persian Gulf
Background: Homocysteine is a non essential amino acid which is derived from metabolism of the essential amino acid, metionin. It has been shown that an elevated serum homocysteine level in adults is associated with vascular diseases.
Ali Movahed +5 more
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