Results 21 to 30 of about 90,248 (215)

Changes in the physical structure and chain dynamics of elastin network in homocysteine-cultured arteries [PDF]

, 2009
The thermal and dielectric properties of the elastin network were investigated in arteries cultured with physiological and pathological concentrations of homocysteine, an aminoacid responsible of histological impairments in human arteries.
Lamy, Edouard, Charpiot, Philippe, Chareyre, Corinne, Lacabanne, Colette, Samouillan, Valérie, Foucault-Bertaud, Alexandrine, Dandurand, Jany, Colette Lacabanne, Edouard Lamy, Valérie Samouillan, Philippe Charpiot, Alexandrine Foucault-Bertaud, Jany Dandurand, Corinne Chareyre   +13 more
core   +1 more source

Importance of Raised Serum Homocysteine Levels in Ischemic Stroke Patients [PDF]

Liaquat National Journal of Primary Care
Background: Around 5.5 million people die from stroke each year, making it the second leading cause of mortality worldwide. Increased homocysteine levels lead to early neurological deteriorations in ischemic stroke and may have an association with other
Rida Batool, Syeda Nosheen Zehra
doaj   +1 more source

Association Between Homocysteine and Vascular Calcification Incidence, Prevalence, and Progression in the MESA Cohort

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background While elevated homocysteine has been associated with calcification in several studies, its importance as a cardiovascular risk factor remains unclear.
Amy B. Karger, Brian T. Steffen, Sarah O. Nomura, Weihua Guan, Parveen K. Garg, Moyses Szklo, Matthew J. Budoff, Michael Y. Tsai   +7 more
doaj   +1 more source

Homocysteine and risk of ischemic heart disease and stroke [PDF]

, 2002
CONTEXT: It has been suggested that total blood homocysteine concentrations are associated with the risk of ischemic heart disease (IHD) and stroke. OBJECTIVE: To assess the relationship of homocysteine concentrations with vascular disease risk.
Homocysteine Studies Collaboration Group, Alfthan G, Clarke R, Homocysteine Studies Collaboration, Homocysteine Studies Collab, ., Tuomilehto J   +5 more
core   +1 more source

NF-kappaB activation is associated with homocysteine-induced injury in Neuro2a cells

BMC Neuroscience, 2008
Background Perinatal exposure to hyperhomocysteinemia might disturb neurogenesis during brain development and growth. Also, high levels of homocysteine trigger neurodegeneration in several experimental models.
Ientile Riccardo, Parisi Giulia, Currò Monica, Condello Salvatore, Ferlazzo Nadia, Caccamo Daniela   +5 more
doaj   +1 more source

Site‐Specific Protein Bioconjugation Through Cellular Incorporation of Noncanonical Amino Acids

Angewandte Chemie, EarlyView.
Genetic code expansion (GCE) enables site‐specific installation of noncanonical amino acids containing bioorthogonal conjugation handles, allowing precise, homogeneous protein modification. This review examines the principles of orthogonal translation, surveys the chemistries available for chemoselective labeling, and highlights emerging multi‐site ...
Rahul Sarkar, Manas Joshi, Abhishek Chatterjee   +2 more
wiley   +2 more sources

Homocysteine causes neuronal leptin resistance and endoplasmic reticulum stress

PLoS ONE, 2022
Abnormally high serum homocysteine levels have been associated with several disorders, including obesity, cardiovascular diseases or neurological diseases.
Arini Isnani Preninka, Karen Kuriya, Kyosuke Yazawa, Michiko Yoshii, Yuhki Yanase, Ralf Jockers, Julie Dam, Toru Hosoi, Koichiro Ozawa   +8 more
doaj  

Homocysteine: A Potential Common Route for Cardiovascular Risk and DNA Methylation in Psoriasis

Chinese Medical Journal, 2017
Objective: Homocysteine is a sulfur-containing amino acid with potential clinical significance. Abnormal homocysteine levels have been found in patients with psoriasis.
Wen-Ming Wang, Hong-Zhong Jin
doaj   +1 more source

Potential Antioxidative Activity of Homocysteine in Erythrocytes under Oxidative Stress

Antioxidants, 2023
Homocysteine is an amino acid containing a free sulfhydryl group, making it probably contribute to the antioxidative capacity in the body. We recently found that plasma total homocysteine (total-Hcy) concentration increased with time when whole blood ...
Mingxin Ye, Hui Li, Hongjun Luo, Yongyin Zhou, Wenhong Luo, Zhexuan Lin   +5 more
doaj   +1 more source

Vitamin B(12) deficiency stimulates osteoclastogenesis via increased homocysteine and methylmalonic acid [PDF]

, 2009
The risk of nutrient deficiencies increases with age in our modern Western society, and vitamin B(12) deficiency is especially prevalent in the elderly and causes increased homocysteine (Hcy) and methylmalonic acid (MMA) levels.
Bravenboer, N., Vaes, Bart L T, Vaes, B.L.T., Everts, V., Wilma T. Steegenga, Bravenboer, Nathalie, Steegenga, W.T., Lute, Carolien, Carolien Lute, de Groot, L.C.P.G.M., Müller, M.R., Henk J. Blom, Dhonukshe-Rutten, R.A.M., de Groot, Lisette C P G M, Dhonukshe-Rutten, R.A., Bart L. T. Vaes, Teun J. de Vries, Blom, Henk J, Nathalie Bravenboer, de Vries, Teun J, Müller, Michael, Everts, Vincent, Rosalie A. Dhonukshe-Rutten, Michael Müller, de Vries, T.J., Lisette C. P. G. M. de Groot, Dhonukshe-Rutten, Rosalie A, Steegenga, Wilma T, Groot, C.P.G.M., de, Lute, C., Blom, H.J., Vries, T.J., de, Vincent Everts, Müller, M.   +33 more
core   +1 more source