Results 31 to 40 of about 87,836 (275)

Mining literature for a comprehensive pathway analysis: A case study for retrieval of homocysteine related genes for genetic and epigenetic studies

Lipids in Health and Disease, 2006
Homocysteine is an independent risk factor for cardiovascular diseases. It is also known to be associated with a variety of complex disorders. While there are a large number of independent studies implicating homocysteine in isolated pathways, the ...
Mahajan Anubha, Sundaramoorthy Elayanambi, Brahmachari Vani, Senthilkumar RD, Sharma Priyanka, Sharma Amitabh, Sengupta Shantanu   +6 more
doaj   +1 more source

Do dietary patterns in older men influence change in homocysteine through folate fortification? The Normative Aging Study [PDF]

, 2009
Objective We aimed to describe the difference in B-vitamin intake and in plasma B-vitamin and homocysteine concentrations before and after folic acid fortification, in relation to dietary patterns. Design The Normative Aging Study (NAS) is a longitudinal
Groot, C.P.G.M., de, Spiro, A., Kromhout, D., Tucker, K.L., Staveren, W.A., van, Knoops, K.T.B.   +5 more
core   +1 more source

Plasma homocysteine levels in patients with liver cirrhosis [PDF]

Vojnosanitetski Pregled, 2013
Background/Aim. Homocysteine (2-amino-4-mercaptobutyric acid) is an amino acid that may be found in small quantities in all cells, and is quantitatively the major methionine metabolite. The most prevalent form is protein-bound homocysteine (about 80%),
Ćulafić Đorđe M., Marković Miroslav Lj., Obrenović Radmila Ž., Mijač Dragana D.   +3 more
doaj   +1 more source

Effects of homocysteine lowering with B vitamins on cognitive aging: meta-analysis of 11 trials with cognitive data on 22,000 individuals. [PDF]

, 2014
BACKGROUND: Elevated plasma homocysteine is a risk factor for Alzheimer disease, but the relevance of homocysteine lowering to slow the rate of cognitive aging is uncertain.
Hankey, G.J., Lewerin, Catharina,, Eussen, SJ, Sarah Parish, Hankey, GJ, Eussen, Simone J. P. M., Dangour, A. D., Halsey, Jim, Bennett, Derrick, Lewington, S., B-Vitamin Treatment Trialists' Collaboration, the, David J Stott, Lewerin, C., Dangour, Alan D, Bennett, D., Galan, P, Graeme J Hankey, B-Vitamin Treatment Trialists’ Collaboration, Dangour, A.D., Bennett, D, Eussen, Simone JPM, Lonn, E., Armitage, J., Spence, J.D., Francine Grodstein, Hankey, G. J., Parish, Sarah, Galan, P., Eussen, Sjpm, Catharina Lewerin, Alan D Dangour, de Groot, L.C., Parish, S., Eva Lonn, Hankey, Graeme J., Clarke, Robert, Halsey, J., Rory Collins, Clarke, R, Derrick Bennett, Spence, J. D., Hankey, Graeme J, Simone JPM Eussen, Spence, J. David, Collins, Rory, Sarah Lewington, Stott, David J, Armitage, Jane, Stott, D. J., Lewington, Sarah, Collins, R, Eussen, S.J., Lonn, E, Murray Skeaff, Lewerin, Catharina, Clarke, R., Robert Clarke, J David Spence, de Groot, C.P.G.M., Grodstein, Francine, Spence, J David, Pilar Galan, Jim Halsey, Eussen, S.J.P.M.; id_orcid, Spence, JD, Dangour, AD, Jane Armitage, Lonn, Eva, Armitage, J, Galan, Pilar, Lewerin, C, Collins, R., Stott, David J., Groot, C.P.G.M., de, Skeaff, M, Dangour, Alan D., Grodstein, F., Halsey, J, Grodstein, F, Skeaff, M., de Groot, LC, de Groot, Lisette C, Eussen, S.J.P.M., Lisette C de Groot, de Groot, L. C., de Groot, Lisette C., Stott, D.J., Stott, DJ, Skeaff, Murray   +88 more
core   +1 more source

Homocysteine and familial longevity: the Leiden Longevity Study.

PLoS ONE, 2011
Homocysteine concentrations are a read-out of methionine metabolism and have been related to changes in lifespan in animal models. In humans, high homocysteine concentrations are an important predictor of age related disease.
Carolien A Wijsman, Diana van Heemst, Maarten P Rozing, P Eline Slagboom, Marian Beekman, Anton J M de Craen, Andrea B Maier, Rudi G J Westendorp, Henk J Blom, Simon P Mooijaart   +9 more
doaj   +1 more source

Changes in the physical structure and chain dynamics of elastin network in homocysteine-cultured arteries [PDF]

, 2009
The thermal and dielectric properties of the elastin network were investigated in arteries cultured with physiological and pathological concentrations of homocysteine, an aminoacid responsible of histological impairments in human arteries.
Lamy, Edouard, Charpiot, Philippe, Chareyre, Corinne, Lacabanne, Colette, Samouillan, Valérie, Foucault-Bertaud, Alexandrine, Dandurand, Jany   +6 more
core   +1 more source

Homocysteine

Comprehensive Therapy, 2002
Homocystemia is a pathological condition that represents a significant role in cardiovascular morbidity and mortality. The epidemiology, pathophysiology, and clinical diagnostics and treatment aspects are described and discussed.
Robert, Hasty, Edward N, Smolar
openaire   +4 more sources

Homocysteine and risk of ischemic heart disease and stroke [PDF]

, 2002
CONTEXT: It has been suggested that total blood homocysteine concentrations are associated with the risk of ischemic heart disease (IHD) and stroke. OBJECTIVE: To assess the relationship of homocysteine concentrations with vascular disease risk.
Homocysteine Studies Collaboration, Homocysteine Studies, Homocysteine Studies Collaboration Group, Alfthan G, Clarke R, Homocysteine Studies Collaboration, Homocysteine Studies Collab, ., Tuomilehto J   +6 more
core   +1 more source

Importance of Raised Serum Homocysteine Levels in Ischemic Stroke Patients [PDF]

Liaquat National Journal of Primary Care
Background: Around 5.5 million people die from stroke each year, making it the second leading cause of mortality worldwide. Increased homocysteine levels lead to early neurological deteriorations in ischemic stroke and may have an association with other
Rida Batool, Syeda Nosheen Zehra
doaj   +1 more source

NF-kappaB activation is associated with homocysteine-induced injury in Neuro2a cells

BMC Neuroscience, 2008
Background Perinatal exposure to hyperhomocysteinemia might disturb neurogenesis during brain development and growth. Also, high levels of homocysteine trigger neurodegeneration in several experimental models.
Ientile Riccardo, Parisi Giulia, Currò Monica, Condello Salvatore, Ferlazzo Nadia, Caccamo Daniela   +5 more
doaj   +1 more source