Results 31 to 40 of about 124,435 (251)
Increased telomere attrition following renal transplantation: impact of anti-metabolite therapy [PDF]
, 2016 Background: The uremic milieu exposes chronic kidney disease (CKD) patients to premature ageing processes. The impact of renal replacement therapy (dialysis and renal transplantation [RTx]) or immunosuppressive treatment regimens on ageing biomarkers has
Bárány, Peter +13 more
core +1 more source
Predicting and Rationalizing Piezoelectricity in Racemic Bioorganic Molecular Crystals
Angewandte Chemie, EarlyView.Racemic molecular crystals, composed of equal mixtures of chiral enantiomeric components, are predicted to exhibit significant piezoelectric responses and favourable mechanical flexibility. This study identifies organic and bioorganic racemates as promising candidates for sustainable, lead‐free materials, enabling next‐generation applications in energy
Shubham Vishnoi, Sarah Guerin
wiley +2 more sources
Elevated Levels of Methylmalonate and Homocysteine in Parkinson's Disease, Progressive Supranuclear Palsy and Amyotrophic Lateral Sclerosis [PDF]
, 2010 Background/Aims: Increasing evidence suggests that elevated levels of homocysteine (Hcy) and methylmalonate (MMA) may be involved in the pathogenesis of neurodegenerative diseases. Methods: The urine levels of MMA and serum levels of Hcy as well as folic
Bötzel, Kai +4 more
core +1 more source
Estrogen and homocysteine [PDF]
Cardiovascular Research, 2002 Cardiovascular diseases are the major causes of illness and death in women. Premenopausal women are relatively protected from coronary artery disease and atherosclerosis as compared to postmenopausal women, and this protection is attributed to the effects of the female sex hormone (estrogen). The vasculature, like the reproductive tissues, bone, liver,
Kamellia R, Dimitrova +3 more
openaire +2 more sources
Angewandte Chemie, EarlyView.We developed a novel domino polymerization to synthesize reductively degradable poly(disulfide)s with tunable side chains. A novel monomer bearing thiolactone and pyridyl disulfide groups reacts with various amines, enabling continuous ring‐opening and disulfide exchange.
Yukiya Kitayama +2 more
wiley +2 more sources
Homocysteine causes neuronal leptin resistance and endoplasmic reticulum stress
PLoS ONE, 2022 Abnormally high serum homocysteine levels have been associated with several disorders, including obesity, cardiovascular diseases or neurological diseases.
Arini Isnani Preninka +8 more
doaj
Potential Antioxidative Activity of Homocysteine in Erythrocytes under Oxidative Stress
Antioxidants, 2023 Homocysteine is an amino acid containing a free sulfhydryl group, making it probably contribute to the antioxidative capacity in the body. We recently found that plasma total homocysteine (total-Hcy) concentration increased with time when whole blood ...
Mingxin Ye +5 more
doaj +1 more source
Effect of Combination Folic Acid, Vitamin B6 , and Vitamin B12 Supplementation on Fracture Risk in Women: A Randomized, Controlled Trial. [PDF]
, 2017 Epidemiologic studies have demonstrated an association of elevated plasma homocysteine levels with greater bone resorption and fracture risk. Vitamins B12 , B6 , and folic acid are cofactors in homocysteine metabolism, and supplementation with B vitamins
Bauer, Douglas C +8 more
core +1 more source
Homocysteine and psoriasis [PDF]
Bioscience Reports, 2019 AbstractPsoriasis is caused by a complex interplay among the immune system, genetic background, autoantigens, and environmental factors. Recent studies have demonstrated that patients with psoriasis have a significantly higher serum homocysteine (Hcy) level and a higher prevalence of hyperhomocysteinaemia (HHcy). Insufficiency of folic acid and vitamin
Xiran Lin, Xianmin Meng, Zhiqi Song
openaire +2 more sources
Homocysteine: A Potential Common Route for Cardiovascular Risk and DNA Methylation in Psoriasis
Chinese Medical Journal, 2017 Objective: Homocysteine is a sulfur-containing amino acid with potential clinical significance. Abnormal homocysteine levels have been found in patients with psoriasis.
Wen-Ming Wang, Hong-Zhong Jin
doaj +1 more source