Results 91 to 100 of about 72,239 (257)

In vivo and in silico models of Drosophila for Parkinson's disease

The FEBS Journal, EarlyView.
In vivo and in silico models of Drosophila offer valuable advantages in the generation, analysis, and interpretation of complex biological data, thereby significantly advancing our understanding of Parkinson's disease. Molecular‐level measurements and phenotypic data from Drosophila are extensively utilised in metabolic network modeling and artificial ...
Müberra Fatma Cesur, Rachel Strazdins, Souvarish Sarkar, Tunahan Çakır   +3 more
wiley   +1 more source

Transfer of the methyl group from N5-methyltetrahydrofolates to homocysteine in Escherichia coli [PDF]

, 1964
JR Guest, S. Friedman, MA Foster, G. Tejerina, D. D. Woods   +4 more
openalex   +1 more source

Levodopa‐Carbidopa Intestinal Gel in an Outpatient Setting: A 10‐Year Experience

Movement Disorders Clinical Practice, EarlyView.
Alessandro Magliozzi, Nicholas Feugas, Yu Yan Poon, Taline Naranian, Louis Liu, Yvonne Tse, Anthony E. Lang, Alfonso Fasano   +7 more
wiley   +1 more source

The molecular mechanisms of defensive‐grade organic acid biosynthesis in ground beetles

Insect Molecular Biology, EarlyView.
Formic acid and methacrylic acid are the primary defensive chemicals in the pygidial gland secretions of Platynus angustatus and Pterostichus moestus, respectively. Comparative transcriptomics suggests the folate cycle and valine catabolism may be involved in the biosynthesis of formic acid and methacrylic acid, respectively.
Adam M. Rork, Sihang Xu, Athula Attygalle, Tanya Renner   +3 more
wiley   +1 more source

EVALUATION OF SERUM HOMOCYSTEINE AS AN INDEPENDENT RISK FACTOR FOR MYOCARDIAL INFARCTION IN YOUNG PATIENTS

National Journal of Medical Research, 2012
Introduction: Abnormal Homocysteine (HCY) level appear to contribute to atherosclerosis by direct toxic effect that damages the arterial linings, interfering with the clotting factors and oxidation of LDL.
Asutosh P Chauhan, Piyush B Tailor, Rachit Joshi, Prakash Bhabhor   +3 more
doaj  

Article Commentary: Retinal Ganglion Cell Loss in Diabetes Associated with Elevated Homocysteine

Ophthalmology and Eye Diseases, 2009
A number of studies have suggested that homocysteine may be a contributing factor to development of retinopathy in diabetic patients based on observed correlations between elevated homocysteine levels and the presence of retinopathy.
Kenneth S. Shindler
doaj   +1 more source

A Comparative Analysis of Creatine, Creatinine, Amino Acid Concentrations and Indispensable Amino Acid Scores of Grain‐Free and Grain‐Inclusive Commercial Extruded Adult Cat Foods

Journal of Animal Physiology and Animal Nutrition, EarlyView.
ABSTRACT Despite its role in energy and amino acid (AA) metabolism, no work has investigated creatine (Cr) content in commercial cat food. This study evaluated the Cr, creatinine (CrN), crude protein (CP) and AA concentrations of 30 commercial extruded cat diets.
Taylor Richards, Ulrike Braun, Anna K. Shoveller, Julia G. Pezzali   +3 more
wiley   +1 more source

The substrate specificity of 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferase [PDF]

, 1969
Earl G. Burton, Jacob Selhub, Warwick Sakami   +2 more
openalex   +1 more source

Genome‐Wide Analysis of DtxR and HrrA Regulons Reveals Novel Targets and a High Level of Interconnectivity Between Iron and Heme Regulatory Networks in Corynebacterium glutamicum

Molecular Microbiology, EarlyView.
Iron is essential for life, yet excessive levels can quickly lead to cellular damage via oxidative stress, underscoring the need for global regulators of iron and heme homeostasis. In this study, we present a genome‐wide analysis of the binding patterns of DtxR and HrrA in Corynebacterium glutamicum.
Aileen Krüger, Ulrike Weber, Julia Frunzke   +2 more
wiley   +1 more source

Elevated homocysteine is negatively correlated with plasma cystathionine β‐synthase activity in givosiran‐treated patients

JIMD Reports
Givosiran is a subcutaneously administered, liver‐targeted RNA interference (RNAi) therapeutic that has been approved for treating acute hepatic porphyria (AHP).
Mark A. Keibler, Gautham V. Sridharan, Marianne T. Sweetser, Simina Ticau   +3 more
doaj   +1 more source