Results 111 to 120 of about 143,735 (277)

Integration of epigenetics into ecotoxicology: insights and fundamental research needs

Biological Reviews, EarlyView.
ABSTRACT Epigenetics refers to heritable changes in genome function that occur without direct alterations to the DNA sequence. A multitude of environmental contaminants can influence the epigenetic marks of a genome. Changes of epigenetic marks including DNA methylation, histone modifications, and non‐coding RNAs can induce alterations at the gene ...
Albano Pinto, Jana Asselman, Patrícia Pereira, Joana Luísa Pereira   +3 more
wiley   +1 more source

Faulty homocysteine recycling in diabetic retinopathy

Eye and Vision, 2020
Background Although hyperglycemia is the main instigator in the development of diabetic retinopathy, elevated circulating levels of a non-protein amino acid, homocysteine, are also associated with an increased risk of retinopathy.
Renu A. Kowluru, Ghulam Mohammad, Nikhil Sahajpal   +2 more
doaj   +1 more source

Neonates born at term with periventricular haemorrhagic infarction: Risk factors and clinical presentation

Developmental Medicine &Child Neurology, EarlyView.
This case series describes infants born near term with periventricular hemorrhagic infarction (PVHI), highlighting seizures as a common early symptom. Neonatal complications during delivery and pro‐thrombotic genetic mutations were slightly more common. MRI‐classified involvement was predominantly in the caudate vein territory.
Aleksandra Zaykova, Jeroen Dudink, Floris Groenendaal, Maarten H. Lequin, Manon J.N.L. Benders, Maria Luisa Tataranno, Elise Roze   +6 more
wiley   +1 more source

Relationship between Sources of Dietary Fiber Intake and Homocysteine Metabolism in Relation to Serum Homocysteine Concentrations

Dietetics
While homocysteine is produced as an intermediate metabolite during methionine metabolism, increased blood homocysteine levels are associated with various diseases.
Akiko Tajima, Yoshinori Kubo, Sayaka Horiguchi, Kumiko Shoji, Yasuo Kagawa, Terue Kawabata   +5 more
doaj   +1 more source

On the Origin of Western Diet Pathologies [PDF]

, 2010
The ratio of the two sulfur-containing amino acids, methionine (Met) and cysteine (Cys), may be a determining factor for which foods contribute to longevity and health. It is shown here that substantially more Met than Cys is consistently found in foods,
John Schloss
core   +1 more source

Accumulation of rare coding variants in genes implicated in risk of human cleft lip with or without cleft palate. [PDF]

, 2019
Cleft lip with/without cleft palate (CLP) is a common craniofacial malformation with complex etiologies, reflecting both genetic and environmental factors. Most of the suspected genetic risk for CLP has yet to be identified. To further classify risk loci
Asrani, Kripa, Marini, Nicholas J, Rine, Jasper, Shaw, Gary M, Yang, Wei   +4 more
core   +2 more sources

Effect of renal impairment on atherosclerosis: only partially mediated by homocysteine [PDF]

, 2015
J. David Spence, Bradley L. Urquhart, Heejung Bang   +2 more
openalex   +1 more source

Serum Homocysteine Level in Parkinson’s Disease and Its Association with Duration, Cardinal Manifestation, and Severity of Disease

Parkinson's Disease, 2018
Background and Purpose. Due to the high prevalence of Parkinson’s disease (PD) in the elderly, a large financial burden is imposed on the families and health systems of countries in addition to the problems related to the mobility impairment caused by ...
Payam Saadat, Alijan Ahmadi Ahangar, Seyed Ehsan Samaei, Alireza Firozjaie, Fatemeh Abbaspour, Sorrayya Khafri, Azam Khoddami   +6 more
doaj   +1 more source

Functional genomics with a comprehensive library of transposon mutants for the sulfate-reducing bacterium Desulfovibrio alaskensis G20. [PDF]

, 2014
UnlabelledThe genomes of sulfate-reducing bacteria remain poorly characterized, largely due to a paucity of experimental data and genetic tools. To meet this challenge, we generated an archived library of 15,477 mapped transposon insertion mutants in the
Arkin, Adam P, Davis, Ronald W, Deutschbauer, Adam, Esquivel, Zuelma, Hazen, Terry C, Kazakov, Alexey E, Kuehl, Jennifer V, Kuehn, Raquel, Nguyen, Michelle, Price, Morgan N, Ray, Jayashree, Wetmore, Kelly M   +11 more
core   +2 more sources

Population References for Plasma Total Homocysteine Concentrations for U.S. Children and Adolescents in the Post-Folic Acid Fortification Era [PDF]

, 2005
Vijay Ganji, Mohammad R Kafai
openalex   +1 more source