Results 11 to 20 of about 142,481 (239)
Association Between Homocysteine and Vascular Calcification Incidence, Prevalence, and Progression in the MESA Cohort [PDF]
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020 Background While elevated homocysteine has been associated with calcification in several studies, its importance as a cardiovascular risk factor remains unclear.
Amy B. Karger +7 more
doaj +3 more sources
Homocysteine Metabolism in Pregnancy and Developmental Impacts
Frontiers in Cell and Developmental Biology, 2022 Homocysteine is a metabolite generated by methionine cycle metabolism, comprising the demethylated derivative of methionine. Homocysteine can be metabolised by the transsulphuration pathway to cystathionine, which requires vitamin B6, or can undergo ...
Stephen W. D’Souza, Jocelyn D. Glazier
doaj +1 more source
Homocysteine levels correlate with AVSS-RigiScan test parameters in men with erectile dysfunction
Basic and Clinical Andrology, 2023 Background Although elevated homocysteine levels have been shown to affect penile erection, the relationship between homocysteine and erection at the tip or base of the penis has not been extensively studied.
Xin Qian +5 more
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Transsulfuration pathway thiols and methylated arginines: the hunter community study [PDF]
, 2013 Background: Serum homocysteine, when studied singly, has been reported to be positively associated both with the endogenous nitric oxide synthase inhibitor asymmetric dimethylarginine [ADMA, via inhibition of dimethylarginine dimethylaminohydrolase ...
Attia, John R. +4 more
core +13 more sources
Clinics in Laboratory Medicine, 2006 Elevated homocysteine levels are associated with a variety of vascular diseases. Specifically, hyperhomocysteinemia is a risk factor for coronary artery disease, cerebrovascular disease, and peripheral arterial disease. Laboratory-based strategies for its detection and quantification have evolved to meet the increasing need for accuracy in risk ...
Bradley A, Maron, Joseph, Loscalzo
+7 more sources
Ability of dietary factors to affect homocysteine levels in mice: a review
Nutrition & Metabolism, 2021 Homocysteine is associated with several diseases, and a series of dietary factors are known to modulate homocysteine levels. As mice are often used as model organisms to study the effects of dietary hyperhomocysteinemia, we collected data about ...
Christine Brütting +3 more
doaj +1 more source
International Journal of Molecular Sciences, 2023 Elevated levels of homocysteine (Hcy), a non-proteinogenic amino acid, may lead to a host of manifestations across the biological systems, particularly the nervous system. Defects in Hcy metabolism have been associated with many neurodegenerative diseases including glaucoma, i.e., the leading cause of blindness. However, the pathophysiology of elevated
Joshua Washington +2 more
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Homocysteine inhibits hepatocyte proliferation via endoplasmic reticulum stress. [PDF]
PLoS ONE, 2013 Homocysteine is an independent risk factor for coronary, cerebral, and peripheral vascular diseases. Recent studies have shown that levels of homocysteine are elevated in patients with impaired hepatic function, but the precise role of homocysteine in ...
Xue Yu +4 more
doaj +1 more source
The International Journal of Biochemistry & Cell Biology, 2000 Homocysteine does not occur in the diet but it is an essential intermediate in normal mammalian metabolism of methionine. Each compound, methionine or homocysteine, is the precursor of the other. Similarly, the synthesis of one is the mechanism for the detoxification of the other.
J D, Finkelstein, J J, Martin
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Estrogen and homocysteine [PDF]
Cardiovascular Research, 2002 Cardiovascular diseases are the major causes of illness and death in women. Premenopausal women are relatively protected from coronary artery disease and atherosclerosis as compared to postmenopausal women, and this protection is attributed to the effects of the female sex hormone (estrogen). The vasculature, like the reproductive tissues, bone, liver,
Kamellia R, Dimitrova +3 more
openaire +2 more sources