Results 11 to 20 of about 143,735 (277)
Association Between Homocysteine and Vascular Calcification Incidence, Prevalence, and Progression in the MESA Cohort [PDF]
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020 Background While elevated homocysteine has been associated with calcification in several studies, its importance as a cardiovascular risk factor remains unclear.
Amy B. Karger +7 more
doaj +3 more sources
Homocysteine levels and treatment effect in the prospective study of pravastatin in the elderly at risk [PDF]
, 2014 Objectives: To assess the effect of preventive pravastatin treatment on coronary heart disease (CHD) morbidity and mortality in older persons at risk for cardiovascular disease (CVD), stratified according to plasma levels of homocysteine.<p></p&
Assendelft, W.J.J. +12 more
core +5 more sources
Transsulfuration pathway thiols and methylated arginines: the hunter community study [PDF]
, 2013 Background: Serum homocysteine, when studied singly, has been reported to be positively associated both with the endogenous nitric oxide synthase inhibitor asymmetric dimethylarginine [ADMA, via inhibition of dimethylarginine dimethylaminohydrolase ...
Attia, John R. +4 more
core +13 more sources
Clinics in Laboratory Medicine, 2006 Elevated homocysteine levels are associated with a variety of vascular diseases. Specifically, hyperhomocysteinemia is a risk factor for coronary artery disease, cerebrovascular disease, and peripheral arterial disease. Laboratory-based strategies for its detection and quantification have evolved to meet the increasing need for accuracy in risk ...
Bradley A, Maron, Joseph, Loscalzo
+7 more sources
Homocysteine Metabolism in Pregnancy and Developmental Impacts
Frontiers in Cell and Developmental Biology, 2022 Homocysteine is a metabolite generated by methionine cycle metabolism, comprising the demethylated derivative of methionine. Homocysteine can be metabolised by the transsulphuration pathway to cystathionine, which requires vitamin B6, or can undergo ...
Stephen W. D’Souza, Jocelyn D. Glazier
doaj +1 more source
Homocysteine levels correlate with AVSS-RigiScan test parameters in men with erectile dysfunction
Basic and Clinical Andrology, 2023 Background Although elevated homocysteine levels have been shown to affect penile erection, the relationship between homocysteine and erection at the tip or base of the penis has not been extensively studied.
Xin Qian +5 more
doaj +1 more source
Ability of dietary factors to affect homocysteine levels in mice: a review
Nutrition & Metabolism, 2021 Homocysteine is associated with several diseases, and a series of dietary factors are known to modulate homocysteine levels. As mice are often used as model organisms to study the effects of dietary hyperhomocysteinemia, we collected data about ...
Christine Brütting +3 more
doaj +1 more source
The International Journal of Biochemistry & Cell Biology, 2000 Homocysteine does not occur in the diet but it is an essential intermediate in normal mammalian metabolism of methionine. Each compound, methionine or homocysteine, is the precursor of the other. Similarly, the synthesis of one is the mechanism for the detoxification of the other.
J D, Finkelstein, J J, Martin
openaire +3 more sources
Homocysteine inhibits hepatocyte proliferation via endoplasmic reticulum stress. [PDF]
PLoS ONE, 2013 Homocysteine is an independent risk factor for coronary, cerebral, and peripheral vascular diseases. Recent studies have shown that levels of homocysteine are elevated in patients with impaired hepatic function, but the precise role of homocysteine in ...
Xue Yu +4 more
doaj +1 more source
Apoptosis of bone marrow mesenchymal stem cells caused by homocysteine via activating JNK signal. [PDF]
PLoS ONE, 2013 Bone marrow mesenchymal stem cells (BMSCs) are capable of homing to and repair damaged myocardial tissues. Apoptosis of BMSCs in response to various pathological stimuli leads to the attenuation of healing ability of BMSCs.
Benzhi Cai +11 more
doaj +1 more source