Results 21 to 30 of about 142,481 (239)
Apoptosis of bone marrow mesenchymal stem cells caused by homocysteine via activating JNK signal. [PDF]
PLoS ONE, 2013 Bone marrow mesenchymal stem cells (BMSCs) are capable of homing to and repair damaged myocardial tissues. Apoptosis of BMSCs in response to various pathological stimuli leads to the attenuation of healing ability of BMSCs.
Benzhi Cai +11 more
doaj +1 more source
Homocysteine and psoriasis [PDF]
Bioscience Reports, 2019 AbstractPsoriasis is caused by a complex interplay among the immune system, genetic background, autoantigens, and environmental factors. Recent studies have demonstrated that patients with psoriasis have a significantly higher serum homocysteine (Hcy) level and a higher prevalence of hyperhomocysteinaemia (HHcy). Insufficiency of folic acid and vitamin
Xiran Lin, Xianmin Meng, Zhiqi Song
openaire +2 more sources
The homocysteine controversy [PDF]
Journal of Inherited Metabolic Disease, 2010 AbstractMild to moderate hyperhomocysteinemia has been identified as a strong predictor of cardiovascular disease, independent from classical atherothrombotic risk factors. In the last decade, a number of large intervention trials using B vitamins have been performed and have shown no benefit of homocysteine‐lowering therapy in high‐risk patients.
Smulders, Y.M., Blom, H.J.
openaire +4 more sources
Elevated plasma homocysteine upon ischemic stroke is associated with increased long-term mortality in women. [PDF]
PLoS ONE, 2017 Ischemic stroke is a leading cause of death worldwide, despite preventive and therapeutic advances during the last twenty years. Blood-borne biomarkers have been studied in association to short- and long-term outcome, in order to investigate possible ...
Ioanna Markaki +3 more
doaj +1 more source
Homocysteine levels and treatment effect in the prospective study of pravastatin in the elderly at risk [PDF]
, 2014 Objectives: To assess the effect of preventive pravastatin treatment on coronary heart disease (CHD) morbidity and mortality in older persons at risk for cardiovascular disease (CVD), stratified according to plasma levels of homocysteine.<p></p&
Assendelft, W.J.J. +12 more
core +3 more sources
Role of homocysteine in the development and progression of Parkinson’s disease
Annals of Clinical and Translational Neurology, 2020 Homocysteine is an essential intermediate product of biochemical reactions that is present in various tissues of the human body. Homocysteine may be associated with the development and progression of Parkinson’s disease.
Xiaoyan Fan +6 more
doaj +1 more source
Homocysteine in cerebrovascular disease: An independent risk factor for subcortical vascular encephalopathy [PDF]
, 2001 Hyperhomocysteinemia is a risk factor for obstructive large-vessel disease. Here, we studied plasma concentrations of homocysteine and vitamins in patients suffering from subcortical vascular encephalopathy (SVE), a cerebral small-vessel disease leading ...
Aufenanger, Johannes +10 more
core +1 more source
Transcobalamin C776G genotype modifies the association between vitamin B12 and homocysteine in older Hispanics. [PDF]
, 2010 Background/objectivesA common polymorphism, C776G, in the plasma B12 transport protein transcobalamin (TC), encodes for either proline or arginine at codon 259.
Allen, LH +4 more
core +2 more sources
Lipids in Health and Disease, 2006 Homocysteine is an independent risk factor for cardiovascular diseases. It is also known to be associated with a variety of complex disorders. While there are a large number of independent studies implicating homocysteine in isolated pathways, the ...
Mahajan Anubha +6 more
doaj +1 more source
Plasma homocysteine levels in patients with liver cirrhosis [PDF]
Vojnosanitetski Pregled, 2013 Background/Aim. Homocysteine (2-amino-4-mercaptobutyric acid) is an amino acid that may be found in small quantities in all cells, and is quantitatively the major methionine metabolite. The most prevalent form is protein-bound homocysteine (about 80%),
Ćulafić Đorđe M. +3 more
doaj +1 more source