Results 101 to 110 of about 1,306,827 (384)
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Veterinární Medicína, 2016 The effect of adding high or low protein content homologous seminal plasma to boar spermatozoa on the progressive motility of the spermatozoa after storage for three days, and at a 1 : 4 dilution ratio was investigated. A total of 32 ejaculates collected
J. Apic +6 more
doaj +1 more source
Network pharmacology and experiment indicated that medicinal food homologous components play important roles in insomnia [PDF]
, 2023 Xiao Xu +5 more
openalex +1 more source
Genes & Development, 2017 Yazinski et al. show that the functions of BRCA1 in homologous recombination and replication fork protection are sequentially bypassed during the acquisition of PARP inhibitor (PARPi) resistance.
Stephanie A. Yazinski +15 more
semanticscholar +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Shanghai yufang yixueObjectiveTo determine the drug sensitivity and molecular typing characteristics of Klebsiella pneumoniae isolated from meat and diarrhea samples in a local area.MethodsSeventy-one strains of K.pneumoniae were isolated from 118 meat food （chicken and pork）
QUE Fengxia +5 more
doaj +1 more source
Simultaneous precise editing of multiple genes in human cells
, 2019 . When double-strand breaks are introduced in a genome by CRISPR they are repaired either by non-homologous end joining (NHEJ), which often results ...
Chintalapati, M. +5 more
core +1 more source
Pacific Journal of Mathematics, 1984 The author is concerned with the following question: Does every closed, orientable, irreducible 3-manifold M with \(\pi_ 1(M)\) infinite have a finite sheeted cover \(\tilde M\) with infinite \(H_ 1(\tilde M) ?\) Such an \(\tilde M\) would be a Haken manifold, so the positive answer to this question would imply existence of finite sheeted Haken covers ...
openaire +2 more sources
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
BioengineeringPlatelet-rich fibrin, the coagulated plasma fraction of blood, is commonly used to support natural healing in clinical applications. The rat calvaria defect is a standardized model to study bone regeneration.
Karol Ali Apaza Alccayhuaman +7 more
doaj +1 more source