Results 101 to 110 of about 1,047,361 (285)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Cross Immunity of a Sonicated Trivalent Avian Colibacillosis Vaccine to Pathogenic Escherichia coli O26 and O78 Strains in Broiler Chickens [PDF]

open access: yesThe Iranian Journal of Veterinary Science and Technology
Colibacillosis outbreaks are a global issue affecting the poultry industry. There is no cross-immunity among the strains of APEC. If a vaccine induces cross-immunity, it will play a key role in preventing colibacillosis.
Sima Alempour Rajabi, Zolfaghar Rajabi
doaj   +1 more source

Symmetric Homology is Representation Homology

open access: yes, 2022
Symmetric homology is a natural generalization of cyclic homology, in which symmetric groups play the role of cyclic groups. In the case of associative algebras, the symmetric homology theory was introduced by Z. Fiedorowicz \cite{F} and was further developed in the work of S. Ault \cite{Au1, Au2}. In this paper, we show that, for algebras defined over
Berest, Yuri, Ramadoss, Ajay C.
openaire   +2 more sources

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Moringa oleifera Alkaloids Inhibited PC3 Cells Growth and Migration Through the COX-2 Mediated Wnt/β-Catenin Signaling Pathway

open access: yesFrontiers in Pharmacology, 2020
Moringa oleifera Lam. (M. oleifera) is valuable plant distributed in many tropical and subtropical countries. It has a number of medicinal uses and is highly nutritious. M.
Jing Xie   +21 more
doaj   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

open access: yesMolecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard   +12 more
wiley   +1 more source

Alotransplante de ilhotas de Langerhans no fígado de ratos submetidos a manipulação tímica com células dendríticas Alogenic islet transplantation on the rat liver after alogenic dendritic cells injection in the thymus

open access: yesArquivos de Gastroenterologia, 2005
RACIONAL: A maior indicação do transplante de pâncreas ou de ilhotas de Langerhans é o diabetes mellitus do tipo I. O processo deve suprir as necessidades de insulina, mantendo os níveis glicêmicos dentro da normalidade.
Eleazar Chaib   +3 more
doaj   +1 more source

Linking numbers of measured foliations

open access: yes, 2001
We generalise the average asymptotic linking number of a pair of divergence-free vector fields on homology three-spheres by considering the linking of a divergence-free vector field on a manifold of arbitrary dimension with a codimension two foliation ...
Kotschick, D., Vogel, T.
core   +3 more sources

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

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