Results 11 to 20 of about 581,114 (248)
Homology operations in symmetric homology [PDF]
The symmetric homology of a unital associative algebra $A$ over a commutative ground ring $k$, denoted $HS_*(A)$, is defined using derived functors and the symmetric bar construction of Fiedorowicz. In this paper we show that $HS_*(A)$ admits homology operations and a Pontryagin product structure making $HS_*(A)$ an associative commutative graded ...
openaire +2 more sources
Nitrogenase and homologs [PDF]
Nitrogenase catalyzes biological nitrogen fixation, a key step in the global nitrogen cycle. Three homologous nitrogenases have been identified to date, along with several structural and/or functional homologs of this enzyme that are involved in nitrogenase assembly, bacteriochlorophyll biosynthesis and methanogenic process, respectively.
Hu, Yilin, Ribbe, Markus W
openaire +5 more sources
29 pages, 3 eps figures, added Report ...
Collinucci, Andrés, Evslin, JARAH J
openaire +3 more sources
Functor homology and homology of commutative monoids [PDF]
The aim of this work is to clarify the relationship between homology theory of commutative monoids constructed 'a la Quillen and technology of Gamma-modules.
Teimuraz Pirashvili, Revaz Kurdiani
openaire +3 more sources
Vascular endothelial‐cadherin as a marker of endothelial injury in preclinical Alzheimer disease
Abstract Objective Endothelial dysfunction is an early and prevalent pathology in Alzheimer disease (AD). We here investigate the value of vascular endothelial‐cadherin (VEC) as a cerebrospinal fluid (CSF) marker of endothelial injury in preclinical AD.
Rawan Tarawneh+5 more
wiley +1 more source
Identification of novel small molecule inhibitors of ETS transcription factors
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla+9 more
wiley +1 more source
The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum
In Saccharomyces cerevisiae, Yeast Amino acid Transporter family members mediate the import of amino acids, ranging from substrate specialists to generalists. Here, we show that the specialist transporter, Lyp1, has a broader substrate spectrum than previously described, with affinity constants spanning from micromolar to millimolar.
Foteini Karapanagioti+3 more
wiley +1 more source
AbstractIn this paper, we provide the theoretical foundation and an effective algorithm for localizing topological attributes such as tunnels and voids. Unlike previous work that focused on 2-manifolds with restricted geometry, our theory is general and localizes arbitrary-dimensional attributes in arbitrary spaces.
Gunnar E. Carlsson, Afra Zomorodian
openaire +3 more sources
Non-homologous functions of the AlkB homologs [PDF]
The DNA repair enzyme AlkB was identified in E. coli more than three decades ago. Since then, nine mammalian homologs, all members of the superfamily of alpha-ketoglutarate and Fe(II)-dependent dioxygenases, have been identified (designated ALKBH1-8 and FTO). While E.
Rune Ougland+3 more
openaire +3 more sources
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source