Results 51 to 60 of about 1,318,508 (390)

Exploring the Mechanism of Action of Sea Buckthorn in the Treatment of Alcoholic Liver Injury Based on Network Pharmacology

open access: yesShipin gongye ke-ji
Objective: To predict the mechanism of sea buckthorn in the treatment of alcoholic liver injury based on network pharmacology, and to verify the efficacy of sea buckthorn in the treatment of alcoholic liver injury by establishing an animal model of ...
Bin DENG   +6 more
doaj   +1 more source

Long-lasting cross-protection against influenza A by neuraminidase and M2e-based immunization strategies [PDF]

open access: yes, 2016
There is mounting evidence that in the absence of neutralizing antibodies cross-reactive T cells provide protection against pandemic influenza viruses. Here, we compared protection and CD8+ T cell responses following challenge with H1N1 2009 pandemic and
Callewaert, Nico   +9 more
core   +2 more sources

Differences of inter-tract correlations between neonates and children around puberty: A study based on microstructural measurements with DTI

open access: yesFrontiers in Human Neuroscience, 2013
The human brain development is a complicated yet well-organized process. Metrics derived from diffusion tensor imaging (DTI), including fractional anisotropy (FA), radial (RD), axial (AxD) and mean diffusivity (MD), have been used to noninvasively access
Virendra eMishra   +6 more
doaj   +1 more source

Safety and immunogenicity of heterologous and homologous inactivated and adenoviral-vectored COVID-19 vaccine regimens in healthy adults: a prospective cohort study

open access: yesHuman Vaccines & Immunotherapeutics, 2022
In light of intermittent supply shortages of individual vaccines and evidence of rare but serious adverse events after vaccination, heterologous regimens for COVID-19 vaccines have gained significant interest. This study aims to assess the reactogenicity
Nasamon Wanlapakorn   +11 more
doaj   +1 more source

Prevalence of Homologous Recombination-Related Gene Mutations Across Multiple Cancer Types.

open access: yesJCO Precision Oncology, 2018
Purpose The prevalence of homologous recombination DNA damage repair (HR-DDR) deficiencies among all tumor lineages is not well characterized. Therapy directed toward homologous recombination DDR deficiency (HRD) is now approved in ovarian and breast ...
Arielle L. Heeke   +8 more
semanticscholar   +1 more source

Mutations in pathways depending on BRCA1 and BRCA2 may increase cancer risks from an environmental carcinogen [PDF]

open access: yes, 2011
Recently, the President’s Cancer Panel [2008-2009] protested that preventive action is not taken when uncertainty exists about potential harm from a chemical, because the US regulatory approach demands that a hazard be incontrovertibly ...
Bernard Friedenson
core   +2 more sources

Preparation, characterization, assembly, and stability of walnut peptide - zinc complexes and its ability to promote zinc transport in Caco-2 cells

open access: yesFood Chemistry: X
Walnut peptides (WP) are promising metal-ion carriers that are expected to improve the bioavailability of dietary micronutrients. In this study, walnut peptide zinc complexes (WP-Zn), a novel zinc supplement differentiated from conventional zinc salts ...
Dong Lin   +7 more
doaj   +1 more source

Homologous Recombination under the Single-Molecule Fluorescence Microscope [PDF]

open access: yes, 2019
Homologous recombination (HR) is a complex biological process and is central to meiosis and for repair of DNA double-strand breaks. Although the HR process has been the subject of intensive study for more than three decades, the complex protein–protein ...
Dhakal, Soma, Gibbs, Dalton R.
core   +2 more sources

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Neovaginoplastia com membrana amniótica na síndrome de Mayer-Rokitansky-Küster-Hauser Neovaginoplasty using amniotic membrane in Mayer-Rokitansky-Küster-Hauser syndrome

open access: yesRevista Brasileira de Ginecologia e Obstetrícia, 2007
OBJETIVO: avaliar resultados da neovaginoplastia com utilização de enxerto amniótico humano em pacientes portadoras da síndrome de Mayer-Rokitansky-Küster-Hauser (MRKH).
Bruno Ramalho de Carvalho   +5 more
doaj   +1 more source

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