Results 71 to 80 of about 1,047,361 (285)
Analytic Inversion of Emission Lines of Arbitrary Optical Depth for the Structure of Supernova Ejecta [PDF]
, 2000 We derive a method for inverting emission line profiles formed in supernova ejecta. The derivation assumes spherical symmetry and homologous expansion (i.e., $v(r) \propto r$), is analytic, and even takes account of occultation by a pseudo-photosphere ...
Adam Fisher +17 more
core +2 more sources
Homology stratifications and intersection homology [PDF]
Geometry & Topology Monographs, 1999 A homology stratification is a filtered space with local homology groups constant on strata. Despite being used by Goresky and MacPherson [Intersection homology theory: II, Inventiones Mathematicae, 71 (1983) 77-129] in their proof of topological invariance of intersection homology, homology stratifications do not appear to have been studied in any ...
Rourke, Colin, Sanderson, Brian
openaire +2 more sources
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Homologous Pairing between Long DNA Double Helices
, 2016 Molecular recognition between two double stranded (ds) DNA with homologous sequences may not seem compatible with the B-DNA structure because the sequence information is hidden when it is used for joining the two strands.
Mazur, Alexey K.
core +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Simultaneous precise editing of multiple genes in human cells
, 2019 . When double-strand breaks are introduced in a genome by CRISPR they are repaired either by non-homologous end joining (NHEJ), which often results ...
Chintalapati, M. +5 more
core +1 more source
International Mathematics Research Notices, 2016 We define and study the invariance properties of homological units. Some applications are given to the derived invariance of Hodge numbers. In particular, we prove that if X and Y are derived equivalent smooth projective varieties of dimension 4 having the same Picard number, then they have the same Hodge numbers.
openaire +2 more sources
Canadian Mathematical Bulletin, 1998 AbstractA new class of homology groups associated to a 3-manifold is defined. The theories measure the syzygies between skein relations in a skein module. We investigate some of the properties of the homology theory associated to the Kauffman bracket.
Bullock, Doug +2 more
openaire +2 more sources
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Frontiers in ImmunologyIntroductionThe durability of Hybrid immunity induced by natural infection and/or COVID-19 vaccines and evidence supporting further booster vaccination are crucial factors for pandemic response, yet remain poorly understood.MethodsWe measured the ...
Maaweya Awadalla +10 more
doaj +1 more source