FIGNL1 Inhibits Non-homologous Chromosome Association and Crossover Formation [PDF]
Frontiers in Plant Science, 2022 Meiotic crossovers (COs) not only generate genetic diversity but also ensure the accuracy of homologous chromosome segregation. Here, we identified FIGNL1 as a new inhibitor for extra crossover formation in rice.
Shuying Yang +13 more
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Cas9/Nickase-induced allelic conversion by homologous chromosome-templated repair in Drosophila somatic cells. [PDF]
Sci Adv, 2022 Repair of double-strand breaks (DSBs) in somatic cells is primarily accomplished by error-prone nonhomologous end joining and less frequently by precise homology-directed repair preferentially using the sister chromatid as a template.
Roy S +9 more
europepmc +2 more sources
CRISPR-induced double-strand breaks trigger recombination between homologous chromosome arms. [PDF]
Life Sci Alliance, 2019 CRISPR–Cas9 enables recombination between homologous chromosome arms at predefined sites and also underscores the need for caution when applying CRISPR technologies in translational medicine.
Brunner E +8 more
europepmc +2 more sources
Competition for Chiasma Formation Between Identical and Homologous (But Not Identical) Chromosomes in Synthetic Autotetraploids of Arabidopsis thaliana [PDF]
Frontiers in Plant Science, 2019 Polyploid organisms provide additional opportunities to study meiosis in a more complex context since more than two potential homologous chromosomes are available.
Pablo Parra-Nunez +2 more
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Chromosome architecture and homologous recombination in meiosis
Frontiers in Cell and Developmental Biology, 2023 Meiocytes organize higher-order chromosome structures comprising arrays of chromatin loops organized at their bases by linear axes. As meiotic prophase progresses, the axes of homologous chromosomes align and synapse along their lengths to form ladder ...
Masaru Ito, Akira Shinohara
doaj +3 more sources
Meiotic cohesin-based chromosome structure is essential for homologous chromosome pairing in Schizosaccharomyces pombe. [PDF]
Chromosoma, 2016 Chromosome structure is dramatically altered upon entering meiosis to establish chromosomal architectures necessary for the successful progression of meiosis-specific events. An early meiotic event involves the replacement of the non-SMC mitotic cohesins
Ding DQ +5 more
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Control of homologous chromosome division in the mammalian oocyte [PDF]
Molecular Human Reproduction, 2009 Homologous chromosomes are segregated during the first meiotic division (meiosis I). Unfortunately, human oocytes are particularly susceptible to mis-segregation errors, so generating aneuploid, often non-viable, embryos. Here we review the cell biology of meiosis I and how homolog disjunction is regulated for mammalian oocytes.
Holt, Janet E., Jones, Keith T.
openaire +3 more sources
BMC Plant Biology, 2019 Background Clubroot, caused by Plasmodiophora brassicae Woronin, is a very important disease of Brassica species. Management of clubroot relies heavily on genetic resistance.
Adrian Chang +7 more
doaj +2 more sources
Homologous chromosome pairing starts at the ends. [PDF]
Plant PhysiolDe Jaeger-Braet J.
europepmc +3 more sources
MJL-1 is a nuclear envelope protein required for homologous chromosome pairing and regulation of synapsis during meiosis in C. elegans. [PDF]
Sci Adv, 2023 Kim HJ, Liu C, Zhang L, Dernburg AF.
europepmc +3 more sources