FIGNL1 Inhibits Non-homologous Chromosome Association and Crossover Formation. [PDF]
Front Plant Sci, 2022 Meiotic crossovers (COs) not only generate genetic diversity but also ensure the accuracy of homologous chromosome segregation. Here, we identified FIGNL1 as a new inhibitor for extra crossover formation in rice.
Yang S +8 more
europepmc +4 more sources
Homologous chromosome pairing starts at the ends. [PDF]
Plant PhysiolDe Jaeger-Braet J.
europepmc +3 more sources
Cas9/Nickase-induced allelic conversion by homologous chromosome-templated repair in Drosophila somatic cells. [PDF]
Sci Adv, 2022 Repair of double-strand breaks (DSBs) in somatic cells is primarily accomplished by error-prone nonhomologous end joining and less frequently by precise homology-directed repair preferentially using the sister chromatid as a template.
Roy S +9 more
europepmc +2 more sources
CRISPR-induced double-strand breaks trigger recombination between homologous chromosome arms. [PDF]
Life Sci Alliance, 2019 CRISPR–Cas9 enables recombination between homologous chromosome arms at predefined sites and also underscores the need for caution when applying CRISPR technologies in translational medicine.
Brunner E +8 more
europepmc +2 more sources
Meiotic telomeres: a matchmaker for homologous chromosomes [PDF]
Genes to Cells, 1998 Telomeres, with their special structures and special schemes of synthesis, are essential for protecting the ends of eukaryotic linear chromosomes during cell proliferation. In addition to this basic function, the meiosis‐specific functions of telomeres have long been inferred from the cytological observations of characteristic chromosome configurations
Yasushi Hiraoka
openalex +4 more sources
Zoo-FISH in the European mole (Talpa europaea) detects all ancestral Boreo-Eutherian human homologous chromosome associations [PDF]
Cytogenetic and Genome Research, 2006 Zoo-FISH with human whole-chromosome paint probes delineated syntenic association of human homologous chromosome segments 3-21, 14-15, 16-19, 4-8, 7-16 and 12-22 (twice) in the European mole (Talpa europaea, Talpidae, Eulipotyphla, Mammalia).
M. Volleth, S. Müller
semanticscholar +3 more sources
Control of homologous chromosome division in the mammalian oocyte. [PDF]
Molecular Human Reproduction, 2009 Homologous chromosomes are segregated during the first meiotic division (meiosis I). Unfortunately, human oocytes are particularly susceptible to mis-segregation errors, so generating aneuploid, often non-viable, embryos.
J. Holt, K. Jones
semanticscholar +4 more sources
Meiotic cohesin-based chromosome structure is essential for homologous chromosome pairing in Schizosaccharomyces pombe. [PDF]
Chromosoma, 2016 Ding DQ +5 more
europepmc +2 more sources
The Novel Gene HOMOLOGOUS PAIRING ABERRATION IN RICE MEIOSIS1 of Rice Encodes a Putative Coiled-Coil Protein Required for Homologous Chromosome Pairing in Meiosis [PDF]
The Plant Cell Online, 2004 We have identified and characterized a novel gene, PAIR1 (HOMOLOGOUS PAIRING ABERRATION IN RICE MEIOSIS1), required for homologous chromosome pairing and cytokinesis in male and female meiocytes of rice (Oryza sativa).
K. Nonomura +6 more
semanticscholar +2 more sources
Nuclear reorganization and homologous chromosome pairing during meiotic prophase require C. elegans chk-2. [PDF]
Genes & Development, 2001 Analysis of mutants defective in meiotic chromosome pairing has uncovered a role for Caenorhabditis elegans chk-2 in initial establishment of pairing between homologous chromosomes during early meiotic prophase.
A. MacQueen, A. Villeneuve
semanticscholar +2 more sources