FIGNL1 Inhibits Non-homologous Chromosome Association and Crossover Formation [PDF]
Meiotic crossovers (COs) not only generate genetic diversity but also ensure the accuracy of homologous chromosome segregation. Here, we identified FIGNL1 as a new inhibitor for extra crossover formation in rice.
Shuying Yang +13 more
doaj +2 more sources
Homologous chromosome pairing starts at the ends [PDF]
Joke De Jaeger‐Braet
europepmc +4 more sources
Chromosome architecture and homologous recombination in meiosis
Meiocytes organize higher-order chromosome structures comprising arrays of chromatin loops organized at their bases by linear axes. As meiotic prophase progresses, the axes of homologous chromosomes align and synapse along their lengths to form ladder ...
Masaru Ito, Akira Shinohara
doaj +3 more sources
A recurrent translocation is mediated by homologous recombination between HERV-H elements [PDF]
Background Chromosome rearrangements are caused by many mutational mechanisms; of these, recurrent rearrangements can be particularly informative for teasing apart DNA sequence-specific factors.
Hermetz Karen E +3 more
doaj +5 more sources
Association of homologous chromosomes during floral development [PDF]
Reduction in chromosome number and genetic recombination during meiosis require the prior association of homologous chromosomes, and this has been assumed to be a central event in meiosis. Various studies have suggested, however, that while the reduction division of meiosis is a universally conserved process, the pre-meiotic association of homologues ...
Luis Aragón-Alcaide +5 more
openalex +3 more sources
Homologous chromosome pairing in Schizosaccharomyces pombe [PDF]
AbstractHomologous chromosome pairing is a central feature of meiosis I, contributing to the correct segregation of chromosomes during meiosis. The fission yeast, Schizosaccharomyces pombe, has been widely used to study meiotic chromosome dynamics, partly because studies in this yeast are simplified due to the lack of post‐pairing synaptic structures ...
Jennifer L. Wells +2 more
openalex +3 more sources
Modeling homologous chromosome recognition via nonspecific interactions [PDF]
In many organisms, most notably Drosophila , homologous chromosomes associate in somatic cells, a phenomenon known as somatic pairing, which takes place without double strand breaks or strand invasion, thus requiring some other mechanism for homologs to recognize each other.
Wallace F. Marshall, Jennifer C. Fung
openaire +4 more sources
PAR-TERRA directs homologous sex chromosome pairing [PDF]
In mammals, homologous chromosomes rarely pair outside meiosis. One exception is the X chromosome, which transiently pairs during X-chromosome inactivation (XCI). How two chromosomes find each other in 3D space is not known. Here, we reveal a required interaction between the X-inactivation center (Xic) and the telomere in mouse embryonic stem (ES ...
Hsueh‐Ping Chu +7 more
openalex +5 more sources
Role of chromosome ends in meiotic stability, recombination and wheat evolution in the context of breeding [PDF]
Wheat is one of the most important crops worldwide, and understanding its genome organisation is crucial for geneticists and breeders. In this study, we examined the dynamic roles of telomeric and subtelomeric regions in wheat, focusing on their ...
A. Gálvez-Galván +2 more
doaj +2 more sources
Site-Specific Sequence Exchange Between Homologous and Non-homologous Chromosomes [PDF]
Transgene integration typically takes place in an easy-to-transform laboratory variety before the transformation event is introgressed through backcrosses to elite cultivars. As new traits are added to existing transgenic lines, site-specific integration can stack new transgenes into a previously created transgenic locus.
Qian Yin, Qian Yin, Ruyu Li, David W. Ow
openaire +3 more sources

