Results 41 to 50 of about 1,161,690 (369)

Analysis of chromosome positions in the interphase nucleus of Chinese hamster cells by laser-UV-microirradiation experiments [PDF]

open access: yes, 1982
Unsynchronized cells of an essentially diploid strain of female Chinese hamster cells derived from lung tissue (CHL) were laser-UV-microirradiated (=257 nm) in the nucleus either at its central part or at its periphery.
B Dutrillaux   +38 more
core   +1 more source

Chromosome-associated RNA–protein complexes promote pairing of homologous chromosomes during meiosis in Schizosaccharomyces pombe

open access: yesNature Communications, 2019
Pairing of homologous chromosomes in meiosis is essential for sexual reproduction. We have previously demonstrated that the fission yeast sme2 RNA, a meiosis-specific long noncoding RNA (lncRNA), accumulates at the sme2 chromosomal loci and mediates ...
Da‐Qiao Ding   +8 more
semanticscholar   +1 more source

Inter- and intra-specific gene-density-correlated radial chromosome territory arrangements are conserved in Old World monkeys [PDF]

open access: yes, 2005
Recently it has been shown that the gene-density correlated radial distribution of human 18 and 19 homologous chromosome territories (CTs) is conserved in higher primates in spite of chromosomal rearrangements that occurred during evolution.
ISHIDA Takafumi   +5 more
core   +1 more source

HO Endonuclease-Initiated Recombination in Yeast Meiosis Fails To Promote Homologous Centromere Pairing and Is Not Constrained To Utilize the Dmc1 Recombinase

open access: yesG3: Genes, Genomes, Genetics, 2018
Crossover recombination during meiosis is accompanied by a dramatic chromosome reorganization. In Saccharomyces cerevisiae, the onset of meiotic recombination by the Spo11 transesterase leads to stable pairwise associations between previously ...
Lina Yisehak, Amy J. MacQueen
doaj   +1 more source

Mouse oocytes carrying metacentric Robertsonian chromosomes have fewer crossover sites and higher aneuploidy rates than oocytes carrying acrocentric chromosomes alone

open access: yesScientific Reports, 2022
Meiotic homologous recombination during fetal development dictates proper chromosome segregation in adult mammalian oocytes. Successful homologous synapsis and recombination during Meiotic Prophase I (MPI) depends on telomere-led chromosome movement ...
Parinaz Kazemi, Teruko Taketo
doaj   +1 more source

Rad54: the Swiss Army knife of homologous recombination? [PDF]

open access: yes, 2006
Homologous recombination (HR) is a ubiquitous cellular pathway that mediates transfer of genetic information between homologous or near homologous (homeologous) DNA sequences. During meiosis it ensures proper chromosome segregation in the first division.
Heyer, Wolf-Dietrich   +3 more
core   +2 more sources

The courtship choreography of homologous chromosomes: timing and mechanisms of DSB-independent pairing

open access: yesFrontiers in Cell and Developmental Biology, 2023
Meiosis involves deep changes in the spatial organisation and interactions of chromosomes enabling the two primary functions of this process: increasing genetic diversity and reducing ploidy level.
Mireia Solé   +4 more
doaj   +1 more source

Meiotic telomeres: a matchmaker for homologous chromosomes [PDF]

open access: yesGenes to Cells, 1998
Telomeres, with their special structures and special schemes of synthesis, are essential for protecting the ends of eukaryotic linear chromosomes during cell proliferation. In addition to this basic function, the meiosis‐specific functions of telomeres have long been inferred from the cytological observations of characteristic chromosome configurations
openaire   +2 more sources

On a break with the X: the role of repair of double-stranded DNA breaks in X-linked disease [PDF]

open access: yes, 2012
The problem of managing free reactive DNA ends in eukaryotic cells has resulted in the development of a number of mechanisms in order to ensure that free ends are rendered non-reactive, or that the double-strand DNA breaks generating the free ends are ...
Cecceroni, Lucia   +2 more
core   +4 more sources

Homologies in human and Macasa fuscata chromosomes revealed by in situ suppression hybridization with human chromosome specific DNA libraries [PDF]

open access: yes, 1992
We established chromosomal homologies between all chromosomes of the human karyotype and that of an old world monkey (Macaca fuscata) by chromosomal in situ suppression (CISS) hybridization with human chromosome specific DNA libraries.
Cremer, Thomas   +3 more
core   +1 more source

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