Frontiers in Cell and Developmental Biology, 2023 Meiosis involves deep changes in the spatial organisation and interactions of chromosomes enabling the two primary functions of this process: increasing genetic diversity and reducing ploidy level.
Mireia Solé +4 more
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Rad54: the Swiss Army knife of homologous recombination? [PDF]
, 2006 Homologous recombination (HR) is a ubiquitous cellular pathway that mediates transfer of genetic information between homologous or near homologous (homeologous) DNA sequences. During meiosis it ensures proper chromosome segregation in the first division.
Heyer, Wolf-Dietrich +3 more
core +2 more sources
Distribution of chromosome 18 and X centric heterochromatin in the interphase nucleus of cultured human cells [PDF]
, 1990 In situ hybridization of human chromosome 18 and X-specific alphoid DNA-probes was performed in combination with three dimensional (3D) and two dimensional (2D) image analysis to study the interphase distribution of the centric heterochromatin (18c and ...
Agard +63 more
core +1 more source
Mouse HFM1/Mer3 is required for crossover formation and complete synapsis of homologous chromosomes during meiosis. [PDF]
PLoS Genetics, 2013 Faithful chromosome segregation during meiosis requires that homologous chromosomes associate and recombine. Chiasmata, the cytological manifestation of recombination, provide the physical link that holds the homologs together as a pair, facilitating ...
Michel F Guiraldelli +4 more
doaj +1 more source
Homologies in human and Macasa fuscata chromosomes revealed by in situ suppression hybridization with human chromosome specific DNA libraries [PDF]
, 1992 We established chromosomal homologies between all chromosomes of the human karyotype and that of an old world monkey (Macaca fuscata) by chromosomal in situ suppression (CISS) hybridization with human chromosome specific DNA libraries.
Cremer, Thomas +3 more
core +1 more source
Distance between homologous chromosomes results from chromosome positioning constraints [PDF]
Journal of Cell Science, 2010 The organization of chromosomes is important for various biological processes and is involved in the formation of rearrangements often observed in cancer. In mammals, chromosomes are organized in territories that are radially positioned in the nucleus. However, it remains unclear whether chromosomes are organized relative to each other.
Heride, Claire +7 more
openaire +5 more sources
Genetic Requirements for Intra-Chromosomal Deletions [PDF]
, 2020 Chromosomal deletions are one of the most dangerous types of DNA damage and often arise as a result of inappropriately repaired DNA double strand breaks (DSB).
McPherson, Matthew
core
Phylogenetic inferences of Atelinae (Platyrrhini) based on multi-directional chromosome painting in Brachyteles arachnoides, Ateles paniscus paniscus and Ateles b. marginatus [PDF]
, 2005 We performed multi-directional chromosome painting in a comparative cytogenetic study of the three Atelinae species Brachyteles arachnoides, Ateles paniscus paniscus and Ateles belzebuth marginatus, in order to reconstruct phylogenetic relationships ...
C. Nagamachi +17 more
core +1 more source
PLoS Computational BiologyDuring meiosis, pairing of homologous chromosomes (homologs) ensures the formation of haploid gametes from diploid precursor cells, a prerequisite for sexual reproduction.
Ariana Chriss +2 more
doaj +1 more source
Extensive DNA end processing by exo1 and sgs1 inhibits break-induced replication.
PLoS Genetics, 2010 Homology-dependent repair of DNA double-strand breaks (DSBs) by gene conversion involves short tracts of DNA synthesis and limited loss of heterozygosity (LOH).
Vanessa A Marrero, Lorraine S Symington
doaj +1 more source